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16 Cards in this Set
- Front
- Back
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Immunosurpressive Drugs
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Cortisone, methotrexate, azathioprine, cyclosporin. Can have side effects and increase risk of infection and cancer.
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Anti-inflammatory drugs
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Aspirin, ibuprofin, naproxen, steroids.
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Plasmapheresis
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Removes cells and harmful molecules from blood circulation.
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Palliative Care
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What most treatments for autoimmine diseases are. Reduce severity of symptoms rather than disease. Goal is to improve quality of life, not cure.
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Autoimmune Hemolytic Anemia
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Cause: Antibody mediated. Antibodys are made against Rh blood group antigens. Causes opsonization and phagocytosis of RBCs.
Symptoms: Hemolysis, anemia |
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Goodpastures Syndrome
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Cause: Antibody mediated. Compliment and antibodies cause inflammation of proteins in kidney glomerulus and lung alveoli.
Symptoms: Nephritis, lung hemorrhages |
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Myasthenia Gravis
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Cause: Antibody mediated. Antibodies attack Ach receptors preventing binding.
Symptoms: Muscle weakness, paralysis. |
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Graves Disease
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Cause: Antibody mediated. Antibodys stimulate TSH receptors.
Symptom: Hyperthyroidism |
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Pernicious Anemia
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Cause: Antibody mediated. Antibodys attack parietal cells, reducing/eliminaing intrinsic factor production. Therefore no V. B12 absorbtion.
Symptoms: B12 necessary for normal RBC development. Get abnormal RBCs and anemia. |
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Type 1 Diabetes
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Cause: Tcell mediated. T cells kill lancreatic islet cells.
Symptoms: Impaired glucose management, vascular disease |
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Rheumetoid Arthritis
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Cause: T cell mediated. Attack of antigens in joints.
Symptoms: Inflammation of joints and erosion of cartilage. |
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Contact Sensitivity (poison ivy)
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Cause: T cell mediated. Attacks proteins in skin.
Symptoms: DTH reaction and rash. |
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Lupus
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Cause: Immune complex disease. Type III hypersensitivity. Attacks DNA and nuclear proteins.
Symptoms: Nephritis, arthritis, vasculitis. |
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Serum Sickness
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Cause: Immune complex disease. Caused by exposure to animal antiserum.
Symptoms: Systemic vasculitis, nephritis, arthritis |
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Arthus Reaction
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Cause: Type of serum sickness. Immune Complex mediated. Type III hypersensitivity Reaction.
Symptoms: Cutaneous Vasculitis. |
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2 Diseases caused by overactive compliment system
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Lack of compliment reg. proteins:Hereditary Angioneurotic Edema, and Paroxysomal nocturnal hemoglobinuria.
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