Mhr Topic 20: Pseudomonas And Zoonotic Gram (-) Bacteria

Front 1

Pseudomonas Lab results (Gram, oxidase, lactose, O2, in situ appearance)

Back 1

-gram - rod
-oxidase +
-Lactose - (only lac - thats ox +)
-Obligate Aerobe
-blue green pus with fruity odor

Front 2

Pseudomonas Lab (where is it and how do people get infected)

Back 2

1) Ubiquitous in nature, found in wet places, has minimal nutritional requirement
2) Contact, consumption or breathing of contaminated water.

Front 3

Who is at risk for Pseudomonas?

Back 3

Is an oportunistic infection:
-Nosocomial
-wounds/burns
-People with CF
-People in whirlpools or tubs

Front 4

Pseudomonas virulence factors

Back 4

1) Pili and flagella - for adherence
2) Glycocalyx/Biofilm slime layer - Inhibits removal from body
3) Enzymes - Proteases and phospholipases
4) Exotoxin A (inhibits protein synth) and endotoxin

Front 5

Is pseudomonas very antibiotic resistant?

Back 5

Yes

Front 6

Brucella (infection)

Back 6

Transmitted via fluids (unpasteurized milk, urine, placental fluid)
Contact via skin abbrassions or milk consumption.
Low infections dose <100

Front 7

Brucella (disease and diagnosis)

Back 7

1) Several days to months incubation period. Fever malaise GI probs. Then weightloss, depression, osteoarticular problems.
2) Key to diagnosis is Undulating Fever - Rises in Day, Decreases at Night)

Front 8

Bruccella virulence factors

Back 8

LPS

Front 9

Francisella tularensis (gram, O2)

Back 9

1) Gram (-)
2) Strict Aerobe

Front 10

Francisella tularensis (vectors, infection, endemic areas)

Back 10

1) Insect vectors, and animal vectors
2) Contact or bites (only need 10 organisms)
3) MO, AK, OK

Front 11

Francisella tularensis (Disease and diagnosis)

Back 11

1) Persistant punched out ulcer, flu like symptoms, buboes
2) History and Serodiagnosis

Front 12

Yersinia pestis (gram, oxidase)

Back 12

gram (-) rod, safety pin shaped, oxidase (-)

Front 13

Yersinia pestis (Vectors and endemic)

Back 13

1) Fleas bite other animals then us.
Urban = rats, Sylvactic = prairie dogs/squirrls.
2) Southwest

Front 14

Yersinia pestis (virulence factors)

Back 14

Tons, capsule is absolutly necessary, also have YOPs which prevent phagocytosis and compliment. Toxins as well.

Front 15

Yersinia pestis (disease)

Back 15

Buboes, fever, edema, septic shock, meningitis, pneumonia (black plague), highly contagous.

Front 16

Bartonella henselae (Disease)

Back 16

Cat scratch fever:
Cutaneous ulcer, fever, enlarged regional lymph nodes.

Front 17

Bartonella quintana (disease)

Back 17

5-Day Relapse:
Cause of trench fever (flu, bone pain, spenomegaly) relapsing fever.

Front 18

Bartonella infection in immunocompromised

Back 18

Systemic small blood vessel infection. Cutaneous lesions

Front 19

Pasteurella multocida (infection and disease)

Back 19

Wound infection from cat or dog bite
Has capsules and LPS; is a non-intracellular bacteria.
Get acute cellulitis, soft tissue infection, can lead to meninigitis and cariac probs.