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11 Cards in this Set
- Front
- Back
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Antipsychotics indication of use
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Treatment of schizo, bipolar, depression, drug induced psychosis & autism.
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Antipsychotics action
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Thought to block dopamine receptors in the brain & thus to decrease dopamine concentration in the CNS. Phenothiazine blocks receptors dopamine binds to in the limbic system & basal ganglia. These centers are associated with emotion, cognitive & motor function.
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Conventional Antipsychotics
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Phenothiazines, Chlorpromazine (Thorazine), Fluphenazine (Prolixin), Thiordazine (Mellaril), Perphenazine (Trilafon), Trifluoperazine (Stelazine), Butyrophenones (Haloperidol). Note**** Prolixin & Haldol have long acting depot IM forms
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Antipsychotic S/E (conventional)
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Dopamine/alpha block: Hypotension, conduction abnormalities, dry mouth, constipation, urinary retention, leucopenia, photosensitivity, rash, NMS, sedation.
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Antipsychotic S/E (conventional)
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Anticholinergic effects, increased prolactin release: gynecomastia & milk production
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Antipsychotic S/E (conventional)
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Receptor Blockade: Dopamine EPS
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Antipsychotic S/E (conventional)
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Endocrine: Amenorrhea, decrease libido, increased appetite, loss fo temp regulation
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Antipsychotic S/E (conventional)
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Anticholinergic: blurred vision,
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Antipsychotic S/E (conventional)
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Histamine: sedation, drowsiness, hypotension, wt gain
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Antipsychotic S/E (conventional)
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Alpha: postural hypotension, reflect tachycardia, dizziness.
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NMS =
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Neuroleptic Malignant Syndrome
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