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17 Cards in this Set
- Front
- Back
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Fructose --> Fructose 6-P |
Fructose from adipose tissue |
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Fructose --> Fructose 1-P |
Fructokinase
Consumes ATP |
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Fructose 1-P --> Glyceraldehyde + DHAP |
Fructose 1-phosphate aldolase |
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Glyceraldehyde --> Glyceraldehyde 3-P |
Triose kinase
Consumes ATP |
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Galactose --> Galactose 1-P |
Galactokinase
Consumes ATP |
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Galactose 1-P + UDP-glucose --> UDP-galactose + Glucose 1-P |
Galactose 1-phosphate uridyl transferase |
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UDP-galactose --> UDP-glucose |
UDP-galactose-4-epimerase |
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Glucose 1-P --> Glucose 6-P |
Phosphoglucomutase |
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Galactosemia is caused by: |
Uridyl transferase deficiency causing accumulation of galactose, converted to galactitol |
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Cataracts are caused by: |
Galactosemia |
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Galactose --> Galactitol |
Aldol reductase
Redox - used NADPH
Aldehyde reduced to alcohol |
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Lactose intolerance is caused by: |
Lactase deficiency, leading to accumulate of GI lactose that microflora metabolize to produce gas and lactic acid (which draws water and causes diarrhea) |
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Regulatory enzymes of glycolysis: |
Hexokinase, phosphofructokinase, and pyruvate kinase |
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Hexokinase inhibited by: |
Glucose 6-P |
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ATP inhibits: |
PFK
Pyruvate kinase |
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AMP activates: |
PFK |
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Fructose 1,6-bisphosphate activates: |
Pyruvate kinase (feedforward stimulation) |
