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38 Cards in this Set

  • Front
  • Back

Metabolism

The totality of an organism's chemical reactions

Metabolic pathway

Begins with specific molecule, which then altered in a series of defined steps, resulting in a certain product, each step of the pathway is catalyzed by a specific enzyme

Catabolic pathways

Release energy by breaking down complex molecules to simpler compounds

Anabolic pathways

Consume energy to build complicated molecules from simpler ones

Energy

Capacity to cause damage


Ex. Light, sound, electricity

Kinetic energy

Energy associated with the relative motion of objects

Thermal energy

Kinetic energy associated with the random movement atoms or molecules

Heat

Thermal energy transfered from one object to another

Potential energy

Energy that matter possesses because its location or structure

Chemical energy

Refers to the potential energy available for release in a chemical reaction

Thermodynamics

Study of energy transformations

First law of thermodynamics

Energy is constant; energy can be transferred and transformed but it cannot be destroyed

Second law of thermodynamics

Every energy transfer or transformed increases the entropy of the universe

Entropy

Measure of disorder

Free energy

Portion of a system's energy that can perform work when temp and pressure are unform throughout the system

Exergonic reaction

Proceeds with a net release of free energy, spontaneous

Endergonic reaction

One that absorbs free energy from its surroundings, non spontaneous

Endergonic reaction

One that absorbs free energy from its surroundings, non spontaneous

Chemical work

The pushing of endergonic reactions that would not occur spontaneously


Ex. Synthesis of polymers from monomers

Transport work

The pumping of substances across membranes against the direction of spontaneous movement

Transport work

The pumping of substances across membranes against the direction of spontaneous movement

Mechanical work

The contraction of muscles, and the movement of chromosomes during cellular reproduction


Ex. Beating of cilia

Energy coupling

Use of exergonic process to drive an endergonic one, usually mediated by ATP

ATP

Ribose (sugar), adenine (nitrogenous base), 3 phosphate group; nucleotides

Phosphorylated intermediate

The recipient molecule with the phosphate group covalently bonded to it (more reactive/stable)

Enzyme

Macromolecule that acts as a catalyst

Catalyst

Chemical agent that speeds a reaction without being consumed by the reaction

Activation energy

Initial investment of energy for starting a reaction, energy required to contort the reactant molecules so that binds can break

Substrate

The reactant an enzyme acts on

Enzyme-substrate complex

A temporary complex formed when an enzyme binds to its substrate molecule(s)

Active site

A restricted region of the enzyme molecule actually binds to the substrate

Cofactors

Nonprotein helpers of catalytic activity;may be bound tightly or loosely to the enzyme

Coenzyme

When a cofactor is an organic molecule (usually vitamin)

Competitive inhibitors

Reduce the productivity of enzymes by blocking substrates from entering active site

Noncompetitive inhibitors

Impede enzymatic reactions by binding to another part of the enzyme; do not directly compete with the substrate to bind to enzyme at active site

Allosteric regulation

Term used to describe Amy case in which a protein's function at one site is affected by the binding of a regulatory molecule at a separate site

Cooperativity

Amplifies the response of enzymes to substrates (allosteric regulation)

Feedback inhibition

A metabolic pathway is halted by the inhibitory binding of its end product to an enzyme that acts early in the pathway