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25 Cards in this Set
- Front
- Back
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where is the site of oxidative phosphorylation?
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mitochondria
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What is oxidative phosphorylation?
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Oxidative phosphorylation, also known as proton-motive force driven ATP synthesis. Oxidative phosphorylation begins with flow of electron in the respiratory chain in mitochondria. Most electrons come from dehydrogenase.
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What is substrate phosphorylation?
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is direct transfer of phosphate groups from intermediates to ADP to form ATP.
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Electron transfer leads to buildup of ___ in inter-membrane space, which drives ATP synthesis.
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H+ ions
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What is called when electron transfer is connected to ATP synthesis?
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Coupling
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True or False- mitochondria matrix is permeable to H+.
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False
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True or False- All electron starts their path from complex 1 of electron transport chain.
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False
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True or False- ATP synthase can catalyze synthesis of ADP.
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True
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True or False- The 4 protein complexes of respiratory chain can be isolated in virto.
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True
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True or False- NADPH are electron acceptors in anabolic reaction.
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False
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True or False- Ubiquinone transfers electron via hydrogen atom.
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True
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True or False- Electron transfer and ATP synthesis are obligately coupled; neither reaction occurs without the other.
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True
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True or False- Iron protoporphyrin (b-type cytochromes) transfers electron via hydride transfer.
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False
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Iron sulfur proteins often contain what kind of bonds?
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disulfate via amino acid sustain
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The final electron acceptor is ___
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O2
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What are the three stages of cellular respiration for catabolism of Fats, Sugars and AAs?
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• The common entry product of
two-carbon fragment is Acetyl- CoA; • Acetyl-CoA is oxidized via the cycle to CO2; • The energy released is well conserved in NADH and FADH2 |
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How does oxidative phophorylation begin?
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begin with the flow of electrons into the respiratory chain.
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Where do most electrons come from?
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dehydrogenase action
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Most dehydrogenases acting in catabolism are specific for what?
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NAD+ as electro acceptors
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Where does NADPH supply electrons to?
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anabolic rxns.
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What are the three types of electron transfers occur
in oxidative phosphorylation? |
(1) direct transfer of electrons, as in the reduction of
Fe3+ to Fe2+; (2) transfer as a hydrogen atom (H+ + e-); (3) transfer as a hydride ion (:H+), which bears two electrons. |
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What is Ubiquinone?
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it is a lipid-soluble benzoquinone with a long isoprenoid side chain
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What block inulin secretion?
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Defective oxidative phosphorylation in pancreatic β cells blocks.
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In the pentose pathway, what is the the pentose ribose 5-phosphate used for?
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RNA, DNA, and coenzymes, such as ATP,
NADH, FADH2, and coenzyme A in rapidly dividing cells (in bone marrow, skin, and intestinal mucosa, and tumors). |
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What wouldn't Pythagoras let hi collegues eat fava beans?
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erythrocytes begin to lyse 24 to 48 hours after ingestion of the beans, releasing free hemoglobin into
the blood. Jaundice and sometimes kidney failure can result. Similar symptoms can occur with ingestion of the antimalarial drug primaquine or of sulfa antibiotics, or following exposure to certain herbicides. |
