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8 Cards in this Set

  • Front
  • Back
LO 1: characterize the five domains of cognitive function
memory
executive function
visuospatial
language
attention
LO 2: relate domains of cognitive function with the neural structures and circuits that subserve them:

Memory function
Medial temporal lobe
o Hippocampus
o Entorhinal cortex

Diencephalon
o Medial dorsal nucleus of thalamus
o MMB

Basal forebrain

Basal ganglia

Prefrontal cortex
LO 2: relate domains of cognitive function with the neural structures and circuits that subserve them:

Executive Function
Frontal association cortices
LO 2: relate domains of cognitive function with the neural structures and circuits that subserve them:

Attention
Prefrontal cortex is key part of attentional network
o Mediates input from multiple cortical and subcortical regions including temporal, occipital and cingulate cortices

Hippocampus

Cerebellum
LO 3: differentiate and characterize the different types of unsuccessful aging:

Dementia
o Impairment in MEMORY + 1 other cognitive domain
o Impairment in social or occupational fxn
LO 3: differentiate and characterize the different types of unsuccessful aging:

Mild Cognitive Impairment
Mild difficulty with memory + some difficulty in judgment, planning, and with established activities – enough to compromise efficient ADLs but NOT sufficient to threaten independent living
LO 4: characterize the nature and neurobiological bases of the most common forms of dementia

Dementia
- Alzheimer’s Disease
- Vascular Dementia
- Lewy-Body Disease
- Frontotemporal Dementias (eg. Picks disease, Progressive Subcortical Gliosis)
LO 4: characterize the nature and neurobiological bases of the most common forms of dementia

Neurobiological Basis of MCI
Altered white matter

Focal loss of neurons in entorhinal cortex and hippocampus