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210 Cards in this Set

  • Front
  • Back
acidosis
an acid–base imbalance characterized by an increase in H+ concentration (decreased blood pH). A low arterial pH due to reduced bicarbonate concentration is called metabolic acidosis; a low arterial pH due to increased PCO2 is respiratory acidosis
active transport
physiologic pump that moves fluid from an area of lower concentration to one of higher concentration; active transport requires adenosine triphosphate (ATP) for energy
alkalosis
an acid–base imbalance characterized by a reduction in H+ concentration (increased blood pH). A high arterial pH with increased bicarbonate concentration is called metabolic alkalosis; a high arterial pH due to reduced PCO2 is respiratory alkalosis
Diffusion
the process by which solutes move from an area of higher concentration to one of lower concentration; does not require expenditure of energy
Hemostasis
a dynamic process that involves the cessation of bleeding from an injured vessel, which requires activity of blood vessels, platelets, coagulation and fibrinolytic systems
Homeostasis
maintenance of a constant internal equilibrium in a biological system that involves positive and negative feedback mechanisms
hydrostatic pressure
the pressure created by the weight of fluid against the wall that contains it. In the body, hydrostatic pressure in blood vessels results from the weight of fluid itself and the force resulting from cardiac contraction
hypertonic solution
a solution with an osmolality higher than that of serum
hypotonic solution
a solution with an osmolality lower than that of serum
isotonic solution
a solution with the same osmolality as serum and other body fluids. Osmolality falls within normal range for serum (280–300 mOsm/kg).
osmolality
the number of osmoles (the standard unit of osmotic pressure) per kilogram of solution. Expressed as mOsm/kg. Used more often in clinical practice than the term osmolarity to evaluate serum and urine. In addition to urea and glucose, sodium contributes the largest number of particles to osmolality.
Osmolarity
the number of osmoles, the standard unit of osmotic pressure per liter of solution. It is expressed as milliosmoles per liter (mOsm/L); describes the concentration of solutes or dissolved particles.
Osmosis
the process by which fluid moves across a semipermeable membrane from an area of low solute concentration to an area of high solute concentration; the process continues until the solute concentrations are equal on both sides of the membrane.
Tonicity
the measurement of the osmotic pressure of a solution; another term for osmolality
Afterload
the amount of resistance to ejection of blood from the ventricle
apical impulse
(also called point of maximum impulse [PMI]): impulse normally palpated at the fifth intercostal space, left midclavicular line; caused by contraction of the left ventricle
baroreceptors
nerve fibers located in the aortic arch and carotid arteries that are responsible for reflex control of the blood pressure
cardiac catheterization
an invasive procedure used to measure cardiac chamber pressures and assess patency of the coronary arteries
cardiac conduction system
specialized heart cells strategically located throughout the heart that are responsible for methodically generating and coordinating the transmission of electrical impulses to the myocardial cells
cardiac output
amount of blood pumped by each ventricle in liters per minute; normal cardiac output is 5 L per minute in the resting adult heart
contractility
ability of the cardiac muscle to shorten in response to an electrical impulse
diastole
period of ventricular relaxation resulting in ventricular filling
ejection fraction
percentage of the end-diastolic blood volume ejected from the ventricle with each heartbeat
hemodynamic monitoring
use of monitoring devices to measure cardiovascular function
hypertension
blood pressure greater than 140/90 mm Hg
hypotension
a decrease in blood pressure to less than 100/60 mm Hg
international normalized ratio (INR)
a standard method for reporting prothrombin levels, eliminating the variation in test results from laboratory to laboratory
myocardial ischemia
condition in which heart muscle cells receive less oxygen than needed
myocardium
muscle layer of the heart responsible for the pumping action of the heart
normal heart sounds
sounds produced when the valves close; normal heart sounds are S1 (atrioventricular valves) and S2 (semilunar valves)
postural (orthostatic) hypotension
a significant drop in blood pressure (usually 10 mm Hg systolic or more) after an upright posture is assumed
preload
degree of stretch of the cardiac muscle fibers at the end of diastole
pulmonary vascular resistance
resistance to right ventricle ejection of blood
radioisotopes
unstable atoms that emit small amounts of energy in the form of gamma rays; used in cardiac nuclear medicine studies
repolarization
return of the cell to resting state, caused by reentry of potassium into the cell while sodium exits the cell
stroke volume
amount of blood ejected from the ventricle per heartbeat; normal stroke volume is 70 mL in the resting heart
systemic vascular resistance
resistance to left ventricle ejection
systole
period of ventricular contraction resulting in ejection of blood from the ventricles into the pulmonary artery and aorta
telemetry
the process of continuous electrocardiographic monitoring by the transmission of radiowaves from a battery-operated transmitter worn by the patient
cardiac stress test
a test used to evaluate the functioning of the heart during a period of increased oxygen demand
depolarization
electrical activation of a cell caused by the influx of sodium into the cell while potassium exits the cell
cardiac stress test
a test used to evaluate the functioning of the heart during a period of increased oxygen demand
depolarization
electrical activation of a cell caused by the influx of sodium into the cell while potassium exits the cell
murmurs
sounds created by abnormal, turbulent flow of blood in the heart
sinoatrial (SA) node
primary pacemaker of the heart, located in the right atrium
venodilating agent
medication causing dilation of veins
acute coronary syndrome (ACS)
signs and symptoms that indicate unstable angina or acute myocardial infarction
angina pectoris
chest pain brought about by myocardial ischemia
angiotensin-converting enzyme (ACE) inhibitors
medications that inhibit the angiotensin-converting enzyme
atherosclerosis
abnormal accumulation of lipid deposits and fibrous tissue within arterial walls and lumen
atheroma
fibrous cap composed of smooth muscle cells that forms over lipid deposits within arterial vessels and that protrudes into the lumen of the vessel, narrowing the lumen and obstructing blood flow; also called plaque
contractility
ability of the cardiac muscle to shorten in response to an electrical impulse
coronary artery bypass graft (CABG)
a surgical procedure in which a blood vessel from another part of the body is grafted onto the occluded coronary artery below the occlusion in such a way that blood flow bypasses the blockage
creatine kinase (CK)
an enzyme found in human tissues; one of the three types of CK is specific to heart muscle and may be used as an indicator of heart muscle injury
high-density lipoprotein (HDL)
a protein-bound lipid that transports cholesterol to the liver for excretion in the bile; composed of a higher proportion of protein to lipid than low-density lipoprotein; exerts a beneficial effect on the arterial wall
ischemia
insufficient tissue oxygenation
low-density lipoprotein (LDL)
a protein-bound lipid that transports cholesterol to tissues in the body; composed of a lower proportion of protein to lipid than high-density lipoprotein; exerts a harmful effect on the arterial wall
metabolic syndrome
a cluster of metabolic abnormalities including insulin resistance, obesity, dyslipidemia, and hypertension that increase the risk of cardiovascular disease
myocardial infarction (MI)
death of heart tissue caused by lack of oxygenated blood flow; if acute, abbreviated as AMI
percutaneous coronary intervention (PCI)
an invasive procedure in which a catheter is placed in a coronary artery, and one of several methods is employed to remove or reduce a blockage within the artery
percutaneous transluminal coronary angioplasty (PTCA)
a type of percutaneous coronary intervention in which a balloon is inflated within a coronary artery to break an atheroma and open the vessel lumen, improving coronary artery blood flow
primary prevention
interventions taken to prevent the development of coronary artery disease
secondary prevention
interventions taken to prevent the advancement of existing coronary artery disease
Stent
a woven mesh that provides structural support to a coronary vessel, preventing its closure
sudden cardiac death
immediate cessation of effective heart activity
thrombolytic
an agent or process that breaks down blood clots
troponin
myocardial protein; measurement is used to assess heart muscle injury
Ablation
purposeful destruction of heart muscle cells, usually in an attempt to control a dysrhythmia
Antiarrhythmic
a medication that suppresses or prevents a dysrhythmia
Automaticity
ability of the cardiac cells to initiate an electrical impulse
Cardioversion
electrical current administered in synchrony with the patient's own QRS complex to stop a dysrhythmia
Chronotropy
rate of impulse formation
Conduction
transmission of electrical impulses from one cell to another
Defibrillation
electrical current administered to stop a dysrhythmia, not synchronized with the patient's QRS complex
Depolarization
process by which cardiac muscle cells change from a more negatively charged to a more positively charged intracellular state
Dromotropy
conduction velocity
dysrhythmia (also referred to as arrhythmia)
disorder of the formation or conduction (or both) of the electrical impulse within the heart, altering the heart rate, heart rhythm, or both and potentially causing altered blood flow
implantable cardioverter defibrillator (ICD)
a device implanted into the chest to treat dysrhythmias
inhibited
in reference to pacemakers, term used to describe the pacemaker withholding an impulse (not firing)
inotropy
force of myocardial contraction
P wave
the part of an electrocardiogram (ECG) that reflects conduction of an electrical impulse through the atrium; atrial depolarization
Ablation
purposeful destruction of heart muscle cells, usually in an attempt to control a dysrhythmia
Antiarrhythmic
a medication that suppresses or prevents a dysrhythmia
Automaticity
ability of the cardiac cells to initiate an electrical impulse
Cardioversion
electrical current administered in synchrony with the patient's own QRS complex to stop a dysrhythmia
Chronotropy
rate of impulse formation
Conduction
transmission of electrical impulses from one cell to another
Defibrillation
electrical current administered to stop a dysrhythmia, not synchronized with the patient's QRS complex
Depolarization
process by which cardiac muscle cells change from a more negatively charged to a more positively charged intracellular state
Dromotropy
conduction velocity
dysrhythmia (also referred to as arrhythmia)
disorder of the formation or conduction (or both) of the electrical impulse within the heart, altering the heart rate, heart rhythm, or both and potentially causing altered blood flow
implantable cardioverter defibrillator (ICD)
a device implanted into the chest to treat dysrhythmias
inhibited
in reference to pacemakers, term used to describe the pacemaker withholding an impulse (not firing)
inotropy
force of myocardial contraction
P wave
the part of an electrocardiogram (ECG) that reflects conduction of an electrical impulse through the atrium; atrial depolarization
Paroxysmal
a dysrhythmia that has a sudden onset and/or termination and is usually of short duration
PP interval
the duration between the beginning of one P wave and the beginning of the next P wave; used to calculate atrial rate and rhythm
PR interval
the part of an ECG that reflects conduction of an electrical impulse from the sinoatrial (SA) node through the atrioventricular (AV) node
Proarrhythmic
an agent (eg, a medication) that causes or exacerbates a dysrhythmia
QRS complex
the part of an ECG that reflects conduction of an electrical impulse through the ventricles; ventricular depolarization
QT interval
the part of an ECG that reflects the time from ventricular depolarization through repolarization
Repolarization
process by which cardiac muscle cells return to a more negatively charged intracellular condition, their resting state
sinus rhythm
electrical activity of the heart initiated by the sinoatrial (SA) node
ST segment
the part of an ECG that reflects the end of the QRS complex to the beginning of the T wave
supraventricular tachycardia (SVT)
a rhythm that originates in the conduction system above the ventricles
TP interval
the part of an ECG that reflects the time between the end of the T wave and the beginning of the next P wave; used to identify the isoelectric line
T wave
the part of an ECG that reflects repolarization of the ventricles
Triggered
in reference to pacemakers, term used to describe the release of an impulse in response to some stimulus
U wave
the part of an ECG that may reflect Purkinje fiber repolarization; usually it is not seen unless a patient's serum potassium level is low
ventricular tachycardia (VT)
a rhythm that originates in the ventricles
chronic conditions:
medical or health problems with associated symptoms or disabilities that require long-term management (3 months or longer)
disability:
restriction or lack of ability to perform an activity in a normal manner; the consequences of impairment in terms of an individual's functional performance and activity. Disabilities represent disturbances at the level of the person (eg, bathing, dressing, communication, walking, grooming).
impairment:
loss or abnormality of psychological, physiologic, or anatomic structure or function at the organ level (eg, dysphagia, hemiparesis); an abnormality of body structure, appearance, and organ or system function resulting from any cause.
secondary conditions or disorders:
preventable physical, mental, or social disorders resulting directly or indirectly from an initial disabling condition
acute coronary syndrome (ACS)
signs and symptoms that indicate unstable angina or acute myocardial infarction
angina pectoris
chest pain brought about by myocardial ischemia
angiotensin-converting enzyme (ACE) inhibitors
medications that inhibit the angiotensin-converting enzyme
atherosclerosis
abnormal accumulation of lipid deposits and fibrous tissue within arterial walls and lumen
atheroma
fibrous cap composed of smooth muscle cells that forms over lipid deposits within arterial vessels and that protrudes into the lumen of the vessel, narrowing the lumen and obstructing blood flow; also called plaque
contractility
ability of the cardiac muscle to shorten in response to an electrical impulse
coronary artery bypass graft (CABG)
a surgical procedure in which a blood vessel from another part of the body is grafted onto the occluded coronary artery below the occlusion in such a way that blood flow bypasses the blockage
creatine kinase (CK)
an enzyme found in human tissues; one of the three types of CK is specific to heart muscle and may be used as an indicator of heart muscle injury
high-density lipoprotein (HDL)
a protein-bound lipid that transports cholesterol to the liver for excretion in the bile; composed of a higher proportion of protein to lipid than low-density lipoprotein; exerts a beneficial effect on the arterial wall
ischemia
insufficient tissue oxygenation
low-density lipoprotein (LDL)
a protein-bound lipid that transports cholesterol to tissues in the body; composed of a lower proportion of protein to lipid than high-density lipoprotein; exerts a harmful effect on the arterial wall
metabolic syndrome
a cluster of metabolic abnormalities including insulin resistance, obesity, dyslipidemia, and hypertension that increase the risk of cardiovascular disease
myocardial infarction (MI)
death of heart tissue caused by lack of oxygenated blood flow; if acute, abbreviated as AMI
percutaneous coronary intervention (PCI)
an invasive procedure in which a catheter is placed in a coronary artery, and one of several methods is employed to remove or reduce a blockage within the artery
percutaneous transluminal coronary angioplasty (PTCA)
a type of percutaneous coronary intervention in which a balloon is inflated within a coronary artery to break an atheroma and open the vessel lumen, improving coronary artery blood flow
primary prevention
interventions taken to prevent the development of coronary artery disease
secondary prevention
interventions taken to prevent the advancement of existing coronary artery disease
stent
a woven mesh that provides structural support to a coronary vessel, preventing its closure
sudden cardiac death
immediate cessation of effective heart activity
thrombolytic
an agent or process that breaks down blood clots
troponin
myocardial protein; measurement is used to assess heart muscle injury
Allograft
heart valve replacement made from a human heart valve (synonym: homograft)
Annuloplasty
repair of a cardiac valve's outer ring
aortic valve
semilunar valve located between the left ventricle and the aorta
autograft
heart valve replacement made from the patient's own heart valve (eg, the pulmonic valve is excised and used as an aortic valve)
cardiomyopathy
disease of the heart muscle
chordoplasty
repair of the stringy, tendinous fibers that connect the free edges of the atrioventricular valve leaflets to the papillary muscles
commissurotomy
splitting or separating fused cardiac valve leaflets
heterograft
heart valve replacement made of tissue from an animal heart valve (synonym: xenograft)
homograft
heart valve replacement made from a human heart valve (synonym: allograft)
leaflet repair
repair of a cardiac valve's movable “flaps” (leaflets)
mitral valve
atrioventricular valve located between the left atrium and left ventricle
orthotopic transplantation
the recipient's heart is removed, and a donor heart is grafted into the same site; the patient has one heart
prolapse (of a valve)
stretching of an atrioventricular heart valve leaflet into the atrium during systole
pulmonic valve
semilunar valve located between the right ventricle and the pulmonary artery
regurgitation
backward flow of blood through a heart valve
stenosis
narrowing or obstruction of a cardiac valve's orifice
total artificial heart
mechanical device used to aid a failing heart, assisting the right and left ventricles
tricuspid valve
atrioventricular valve located between the right atrium and right ventricle
valve replacement
insertion of a device at the site of a malfunctioning heart valve to restore blood flow in one direction through the heart
valvuloplasty
repair of a stenosed or regurgitant cardiac valve by commissurotomy, annuloplasty, leaflet repair, or chordoplasty (or a combination of procedures)
ventricular assist device
mechanical device used to aid a failing right or left ventricle
xenograft
heart valve replacement made of tissue from an animal heart valve (synonym: heterograft)
Aldosterone
hormone synthesized and released by the adrenal cortex; causes the kidneys to reabsorb sodium
antidiuretic hormone (ADH)
hormone secreted by the posterior pituitary gland; causes the kidneys to reabsorb more water; also called vasopressin
anuria
total urine output less than 50 mL in 24 h
bacteriuria
bacteria in the urine; bacterial count higher than 100,000 colonies/mL
creatinine
endogenous waste product of muscle energy metabolism
dysuria
painful or difficult urination
frequency
voiding more frequently than every 3 h
Glomerulus
tuft of capillaries forming part of the nephron through which filtration occurs
glomerular filtration rate (GFR)
volume of plasma filtered at the glomerulus into the kidney tubules each minute; normal rate is approximately 120 mL/min
hematuria
red blood cells in the urine
micturition
urination or voiding
nephron
structural and functional unit of the kidney responsible for urine formation
nocturia
awakening at night to urinate
oliguria
total urine output less than 400 mL in 24 h
proteinuria
protein in the urine
pyuria
white blood cells in the urine
renal clearance
volume of plasma that the kidneys can clear of a specific solute (eg, creatinine); expressed in milliliters per minute
renal glycosuria
recurring or persistent excretion of glucose in the urine
specific gravity
reflects the weight of particles dissolved in the urine; expression of the degree of concentration of the urine
tubular reabsorption
movement of a substance from the kidney tubule into the blood in the peritubular capillaries or vasa recta
tubular secretion
movement of a substance from the blood in the peritubular capillaries or vasa recta into the kidney tubule
urea nitrogen
nitrogenous end product of protein metabolism
urinary incontinence
involuntary loss of urine
acute tubular necrosis:
type of acute renal failure in which there is actual damage to the kidney tubules
anuria:
total urine output less than 50 mL in 24 hours
arteriovenous fistula:
type of vascular access for dialysis; created by surgically connecting an artery to a vein
arteriovenous graft:
type of surgically created vascular access for dialysis by which a piece of biologic, semibiologic, or synthetic graft material connects the patient's artery to a vein
azotemia:
concentration of urea and other nitrogenous wastes in the blood
continuous ambulatory peritoneal dialysis (CAPD):
method of peritoneal dialysis whereby a patient performs four or five complete exchanges or cycles throughout the day
continuous cyclic peritoneal dialysis (CCPD):
method of peritoneal dialysis in which a peritoneal dialysis machine (cycler) automatically performs exchanges, usually while the patient sleeps
continuous renal replacement therapy (CRRT):
variety of methods used to replace normal kidney function by circulating the patient's blood through a filter and returning it to the patient
continuous venovenous hemodialysis (CVVHD):
form of continuous renal replacement therapy that results in removal of fluid and waste products; venous blood circulates through a hemofilter and returns to the patient
continuous venovenous hemofiltration (CVVH):
form of continuous renal replacement therapy that primarily results in removal of fluid; venous blood circulates through a hemofilter and returns to the patient
dialysate:
solution that circulates through the dialyzer in hemodialysis and through the peritoneal membrane in peritoneal dialysis
dialyzer:
“artificial kidney” or dialysis machine; contains a semipermeable membrane through which particles of a certain size can pass
diffusion:
movement of solutes (waste products) from an area of higher concentration to an area of lower concentration
end-stage renal disease (ESRD):
progressive, irreversible deterioration in renal function that results in retention of uremic waste products
glomerulonephritis:
inflammation of the glomerular capillaries
hemodialysis:
procedure during which a patient's blood is circulated through a dialyzer to remove waste products and excess fluid
interstitial nephritis:
inflammation within the renal tissue
nephrosclerosis:
hardening of the renal arteries
osmosis:
movement of water through a semipermeable membrane from an area of lower solute concentration to an area of higher solute concentration
peritoneal dialysis:
procedure that uses the lining of the patient's peritoneal cavity as the semipermeable membrane for exchange of fluid and solutes
peritonitis:
inflammation of the peritoneal membrane (lining of the peritoneal cavity)
pyelonephritis:
inflammation of the renal pelvis
ultrafiltration:
process whereby water is removed from the blood by means of a pressure gradient between the patient's blood and the dialysate
uremia:
an excess of urea and other nitrogenous wastes in the blood
urinary casts:
proteins secreted by damaged kidney tubules
Classifying Urinary Tract Infections
Urinary tract infections (UTIs) are classified by location: the lower urinary tract (which includes the bladder and structures below the bladder) or the upper urinary tract (which includes the kidneys and ureters). They can also be classified as uncomplicated or complicated UTIs.
Classifying Urinary Tract Infections: Lower UTI
Cystitis, prostatitis, urethritis
Classifying Urinary Tract Infections: Upper UTIs
Acute pyelonephritis, chronic pyelonephritis, renal abscess, interstitial nephritis, perirenal abscess
Classifying Urinary Tract Infections: Uncomplicated Lower or Upper UTIs
Community-acquired infection; common in young women and not usually recurrent
Classifying Urinary Tract Infections: Complicated Lower or Upper UTIs
Often nosocomial (acquired in the hospital) and related to catheterization; occur in patients with urologic abnormalities, pregnancy, immunosuppression, diabetes mellitus, and obstructions and are often recurrent