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1144 Cards in this Set
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- 3rd side (hint)
Pleural Effusions
(2) |
Malignant
Pneumo |
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Secondary medical Tx for chronic stable angina after first 5 (2)
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1) If bp room add CCB
2) If refractory add Ranolazine |
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Dx Irregularly irregular rhythm, with no P waves
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Afib
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Who should get coronary angiography?
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1) Lifestyle limiting angina despite medical tx
2) Markedly positive results on non-invasive stress testing 3) hx of Vtach 4) hx of Non specific CP with recurrent hospitalizations |
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Who should get coronary Ca testing?
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Intermediate risk group (10-20% framingham risk score)
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Dx short PR and delta wave
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Wolf Parkinson White
(n.b. can become either orthodromic or antidromic AVRT) |
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Dx Wide QRS tachycardia in setting of known hx of ischemic damage
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VTach
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Tx for Left NSTEMI
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Beta blocker
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Dx New murmur and respiratory after recent MI (2). Dx study? Tx?
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1) Acute MR
2) VSD Dx study is Echo Tx is IABP |
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Dx STEMI, respiratory distress, hypotension, new systolic murmur, and thrill.
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Ventricular Septal defect
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Dx 1-4 days after MI, heart failure, tamponade or pulseless electrical activity.
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Ventricular free wall rupture
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Dx Afib or Aflutter spurts between a baseline of bradycardia
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Tachy-brady (a type of sick sinus sx)
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Dx Baseline bradycaria with dropped beats
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Sick sinus sx (sinoatrial node dysfunction)
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Dx Drug induced heart block
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Donepezil (ACh esterase inhibitor) causes increased vagal tone, bradycardia, and AV block
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Tx for Hemodynamically unstable patients with arrhythmia
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Electrical cardioversion
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Dx study for Aflutter or AVNRT
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Adenosine bolus
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Dx study for Sinus tachycardia
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Find underlying cause (e.g. TSH)
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What is the CHADS2 risk score?
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CHF
HTN Age >75 years Diabetes Stroke or TIA (2 points) -3 or greater get chronic anti-coagulation tx (warfarin) *1-2 consider ASA vs warfarin |
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Tx chronic Afib
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Beta blocker (or rhythm control e.g. verapamil) and Warfarin
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Dx study and tx for asymptomatic PVCs
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No studies or therapy needed
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Tx for symptomatic PVCs
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Beta blocker or CCB (e.g. verapamil)
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Indication for ICD in CHF
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EF less than 35%
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Indications for pacemaker
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1) Sick Sinus
2) symptomatic bradycardia due to 2nd or 3rd degree AV block |
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Tx for Cardiac arrest (Ventricular arrhythmias)
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Medical management
1) ASA 2) Beta blocker 3) Statin 4) Plavix 5) ACE-I |
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Dx Recurrent syncope with cardiac arrest with family history of sudden death
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Long QT syndrome
(cardiac arrest is in form of torsade de pointe) |
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Indication for Digoxin tx
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Class III or IV heart failure (has no improved mortality, just keeps people out of hospital and makes them feel better)
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Dx Dyspnea, S3 or S4, displaced apical impulse, and EF less than 45% after delivery
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Peripartum cardiomyopathy
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Dx study for new onset CHF (DOE or orthopnea or edema) in the setting of angina (including stable) +/-abnormal EF
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Coronary angiography
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Dx study for New onset CHF
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Echo
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Tx for Class I or II CHF (2)
(even if asymptomatic) |
1) ACE-I
2) Beta blocker 3) Amlodipine only if refactory sx on 1 and 2 |
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Suitable substitute for spironolactone in Class III or IV CHF (bc they got gynecomastia)
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Epleronone
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Tx for Class III or IV CHF
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1) ACE-I
2) Beta blocker 3) Spironolactone |
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Dx Aortic regurg in pt with prosthetic valve
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Prosthetic valve failure
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Dx split S2, right ventricular heave
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Atrial septal defect
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Dx opening snap, low pitched middiastolic murmur best heard over mitral valve
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Mitral stenosis
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Dx and Tx for Short, soft (less than 3), midsystolic murmur in elderly patient
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Usually aortic stenosis. No management needed.
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Diagnostic criteria for DM
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1) HbA1C greater than 6.5
2) Fasting glucose over 125 3) Random glucose over 200 4) 2 hour glucose tolerance test over 200 |
All of these have to be done twice except random BG with signs of hyperglycemia
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Tx Prediabetes
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Lifestyle modifications
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Dx chronic pancreatitis with diabetes
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Secondary diabetes
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Tx Initial for T2DM
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Metformin (and lifestyle modification)
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Tx Inpatient for controlling hyperglyecemia
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Long acting insulin with rapid acting insulin before meals (ISS)
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Tx for proliferative diabetic retinopathy or macular edema
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Laser photocoagulation
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Tx for chronic hypogycemia in DM
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Long acting and rapid acting prandial insulin
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Dx BG over 250, anion gap acidosis (less than 7.3), bicarb less than 15, and positive serum or urine ketones.
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Diabetic ketoacidosis (DKA)
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Dx BG over 600, ph more than 7.3, bicarb more than 15, serum osmolality greater than 320, and absent urine or serum ketones.
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Hyperglycemic hyperosmolar non-ketosis (HHNK)
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Tx HHNK
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IV fluids and identifying underlying cause
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Tx DKA
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Insulin drip
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Dx soft, non-tender, non-pruritic plaques on eyelids
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Xanthelasma (see in familial dyslipidemia)
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Tx for Isolated low HDL
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Lifestyle changes:
1) Exercise 2) Smoking cessation 3) Weight loss |
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LDL goal for 0 or 1 CV risk factor
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Less than 160
|
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LDL goal for a diabetic
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Less than 100
(diabetes is a CVD equivalent) |
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LDL goal for pts with hx of CVA or TIA
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Less than 100
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Mgmt for hypothyroidism
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Treat - Levothyroxine
Hashimoto disease is the most common cause of hypothyroidism, confirmation via TPO antibody unnecessary. |
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Mgmt of Thyroid nodule
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If greater than 1 cm --> biopsy
If less than 1 cm, biopsy only if cancer risk hx |
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Mgmt of Hypothyroidism in pregnacny
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Monitor, bc Thyroxine requirements go up 30-50%, want T4 1.5 normal
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Tx for Grave's disease
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Methimazole and Beta blocker
(better than radiation bc can achieve euthyroid. Also better than PTU) |
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Mgmt of new Hyper or Hypothyroid post partum
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Recheck TSH and T4 to diagnose Postpartum Thyroiditis
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Mgmt abnormal thyroid studies in the setting of acute illness
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Recheck TSH and T4 to diagnose Euthyroid Sick Syndrome
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Mgmt of incidentally discovered adrenal adenoma in asymptomatic patient
|
Get plasma-free metanephrine levels and overnight dexamethasone suppression test
(want to rule out hypersecretion of glucocorticoids and catecholamines) |
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Dx study for Resistant HTN and hypokalemia
|
Serum aldosterone to plasma renin activity ratio to diagnose Primary Hyperaldosteronism
|
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Dx study for High dose dexamethasone sensitive elevated ACTH
|
MRI of pituitary
|
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Dx ACTH dependent hypercortisolism
1) High dose dexamethasone resistant 2) High dose dexamethasone sensitive |
1) Ectopic ACTH tumor
2) Pituitary tumor |
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Mgmt of Palpitations, sweating, HA, HTN
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Abdominal CT scan to confirm Dx of Pheochyromocytoma
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Dx low ACTH, low cortisol, and high glucocorticoids in setting of exogenous corticosteroids
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Adrenal insufficiency due to exogenous corticosteroids
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Tx for Pts with adrenal insufficiency in setting of stress (as from illness or surgery)
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Stress level doses of corticostreroids (Hydrocortisone or Dexamethasone)
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Tx for Osteoporosis
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Vitamin D, Ca supplementation, Bisphosponates (or zoledronate annually if cannot tolerate bisphosphonates)
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When and with what to screen for osteoperosis
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Screen with DEXA in women over 65 or women 60-65 with increased risk of osteoperosis (i.e. weight below 154 lbs)
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Tx for Osteoporosis prevention
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Vit D and Ca
|
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Bone mineral density T score cutoffs for Osteopenia and Osteoperosis
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Osteopenia: -1 to -2.5
Osteoperosis: -2.5 or more |
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Dx unilateral flank pain, n/v, gross or microscopic hematuria
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Nephrolithiasis
|
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Dx study for Nephrolithiasis
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Helical abdominal CT scan
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Dx study for Acute abdominal pain
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Supine and upright abdominal radiographs (to look for air fluid level --> bowel obstruciton, and free peritoneal air --> perforated bowel)
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Dx Abdominal pain, back pain, syncope
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Abdominal aortic aneurysm
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Dx Recurrent abdominal pain or discomfort, relieved with defecation, with diarrhea
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Irritable Bowel Syndrome
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Tx for Irritable bowel syndrome
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Fiber and/or polyethylene glycol with reassurance
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Dx crampy abdominal pain, with bloody stool, in eledery atherosclerotic patients
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Ischemic colitis
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Mgmt LLQ pain, fever, leukocytosis
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Contrast enhanced CT scan to confirm Diverticulitis
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Mgmt Chronic upper abdominal pain radiating to back, diabetes, steatorrhea, pancreatic calcifications
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Abdominal CT to look for pancreatic calcifications to confirm Chronic Pancreatitis
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Dx Thrombotic microangiopathy (schistocytes, elevated retic count, elevated LDH) and Thrombocytopenia
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Hemolytic Uremic Syndrome
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Dx Diarrhea and tenesmus within 6 weeks of radiation therapy
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Radiation proctitis
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Dx mid-epigastric abdominal pain, postprandial diarrhea, +/-DM
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Chronic pancreatitis
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Alarm criteria in IBS
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1) Fever
2) Weight loss 3) Blood in stool 4) Abnormal PE 5) FHx of IBD or Colon ca 6 Pain or diarrhea that interferes with sleep |
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Dx 10-15 stool/day, lower abdominal pain, cramping, fever, leukocytosis in setting of Abx
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C Diff
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Tx for Salmonella gastroenteritis
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Self limiting, no tx
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Dx Anti-mitochondrial Ab
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Primary Biliary Cirrhosis
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Tx for Primary Billiary cirrhosis
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Ursodeoxycholic acid
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Which liver disease is associated with UC and Crohn's
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Primary sclerosing cholangitis
|
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Beading of the biliary duct
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PSC
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Pattern of bilirubin elevation
1) Prehepatic 2) Intrahepatic 3) Posthepatic |
1) Prehepatic - Unconjugated hi
2) Intrahepatic - Both hi 3) Posthepatic - Conjugated hi |
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Dx Unconjugated hyperbilirubinemia with normal Hgb levels and otherwise normal LFTs
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Gilbert Syndrome
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Tx for Symptomatic gallstone disease
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Cholecystectomy
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Dx Elevated bilirubin and alkphos with IBD
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PSC
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Dx fever, jaundice, RUQ pain and common bile duct obstruction
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Acute cholangitis
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Dx biliary colic, Murphy sign, fever, leukocytosis, mild biliruibin and AST/ALT elevation, thickened gallbladder wall.
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Acute cholesystitis
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Tx for Gallstone pancreatitis
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ERCP with sphincterotomy and stone extraction
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Dx epigastric pain radiating to back, n/v, fever, tachycardia, abdominal distension, hypoactive bowel sounds.
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Acute pancreatitis
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Dx Stones in gallbladder, dilated bile duct, and elevated AST/ALT with acute pancreatitis.
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Acute pancreatitis due to gallstones
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Tx for Severe acute pancreatitis
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Enteral nutrition with nasojejunal feeding tube
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Mgmt GERD sx with dysphagia
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Upper endoscopy
(Dysphagia is an alarm sx) |
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Tx Erosive Esophagitis
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PPI
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Dx study for gastric ulcer
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Biopsy
(all ulcers should be biopsied for possible malignancy) |
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Mgmt of dyspepsia with NSAIDs
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Stop the NSAID
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Tx for Functional dyspepsia
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PPI
(i.e. dyspepsia/gastritis without visible organic pathology) |
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Dx study for GI Bleed of unknown etiology after endoscopy and colonoscopy
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Repeat upper endoscopy
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Dx LLQ pain, urgent defecation, red or maroon rectal bleeding not requiring transfusion usually in older people
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Colonic ischemia
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Mgmt of Upper GI bleed after fluid resuscitation
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Upper endoscopy for Diagnosis, Prognosis, and possible therapy
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Tx for GI bleeding in hemodynamically unstable patients
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Fluid resuscitation
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Dx Painless lower GI bleeding
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Diverticulosis and vascular ectasia
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Dx BRBPR and pain with defecation
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Anal fissure
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Screening for chronic Hep B infection
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Liver ultrasound to look for hepatocellular ca
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Dx Acute hepatitis, fatigue, n/v, jaundice, AST/ALTs over 1000.
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Hepatitis A
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Dx AST;ALT ratio greater than 2, elevated alk phos
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Alcoholic hepatitis
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Dx Elevated AST/ALTs, hi GGT, mild bilirubinemia, mildly elevated alk phos, present of auto antibodies.
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Autoimmune hepatitis
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Dx Positive HBsAg and Anti-HBc IgM
|
Acute HepB
(The IgM tells you its acute and not chronic infxn) |
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Dx anti-hepatitis C Ab
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Exposure to Hep C or vaccine
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Dx Cirrhosis, obesity, T2DM, and hyperlipidemia
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Non-Alcoholic Steatohepatitis
NASH |
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Dx UC and marked elevation in alk phos
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PSC
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Dx Ascitic fluid analysis showing serum to ascites albumin gradient greater than 1.1
|
Portal hypertension
(caused by Liver disease, such as cirrhosis, right sided HF (congestive hepatopathy), or Budd-Chiari) |
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Tx for Hepatic Encephalopathy
|
Lactulose
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Dx kidney dysfunction in setting of portal htn after exclusion of prerenal azotemia, intra renal disease, and renal obstruction.
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Hepatorenal syndrome
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Dx small, exquisitely tender nodules on shins in IBD
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Erythema nodosum
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Dx Contiguous inflammation of rectum proximally
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UC (Ulcerative colitis)
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Tx for Ulcerative colitis
|
Mesalamine
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Dx Chronic watery diarrhea without bleeding without findings on colonoscopy
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Microscopic colitis
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Which test characteristics are robust or sensitive to prevalence.
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Robust - Sensitivity, Specificity, LR
Sensitive - PPV,. NPV |
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What is the relationship between LRs and Post Test Probability
|
LRs of 2, 5, and 10 increase Post test probability 15, 30, and 45% respectively
|
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Screening recommendation for AAA
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All men 65-75 who have ever smoked
|
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Flu vaccine recommendations for COPD
|
All COPD patients regardless of age
|
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Pneumovax recommendations
|
1) Anyone over 65
2) Smokers, COPD, or asthma can be younger 3) RE-Vaccination in everyone over 65 if last vaccination was more than 5 years ago AND before 65. 4) RE-Vaccination in immunosuppressed people if first vaccine more than 5 years ago |
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What is the best end point for any trial?
|
Mortality
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Zoster vaccine recommendations
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All patients over 60 regardless of prior varicella/zoster hx
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HPV vaccine recommendations
|
All women 9-26
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Colon Ca screening recommendations
|
Starting at age 50
1) Colonoscopy every 10 years 2) Flex sig every 5 years with home FOBT every 3 years 3) Annual home FOBT |
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Dx Syncope in ischemic HF
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VTach
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How to diagnose orthostatic hypotension
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Drop in systolic BP of 20 or 10 diastolic after 3 minutes of standing
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Dx Syncope, nausea, lightheadedness, diaphoresis
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Vasovagal syncope (situational)
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Dx LOC irrespective of body position without preceding symptoms
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Cardiac arrhythmia
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Dx study for infrequent syncope
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Implantable loop recorder
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Tx for Depression after failing 1 antidepressant
|
A different antidepressant
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Tx for Depressive sx of 2 weeks more than 8 weeks after death of loved one
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Pharmacologic antidepressants
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Tx for Acute cocaine intoxication
|
Benzodiazepine
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Tx for short term alcohol dependence
|
Naltrexone
|
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Tx for Acute opioid intoxication
|
Naloxone (narcan)
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Tx for Spinal stenosis with neurologic deficits and pain refractory to NSAIDs and PT
|
Surgery
|
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Dx study for Vertebral osteomyelitis
|
MRI
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Tx for Acute non-specific low back pain
|
NSAIDs or Acetaminophen
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Dx Back pain, muscle weakness, and bowel or bladder incontinence
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Spinal cord compression
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Dx study for Spinal cord compression
|
MRI of spine
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Mgmt Cough variant asthma
|
Albuterol inhaler trial for tx and dx
|
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Mgmt for Chronic cough in non-smoker
|
Antihistamine/decongestant combination
|
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2 Most common causes of hemoptysis
|
1) Bronchitis
2) Malignancy |
|
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Dx study for Hemoptysis with and without alarms for malignancy
|
1) CXR
2) If over 40, or more than 1 week, or 40 pyhx than Chest CT |
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Tx Acute bronchitis
|
Symptom management
|
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Effects of smoking cessation on lung function (2)
|
1) Absolute improvement (minor)
2) Decreased rate of decline (major) |
|
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Tx for Smoking cessation
|
Varenicline
(Bupropion and nortriptyline effective but less so) |
|
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Indications for bariatric surgery
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1) BMI over 40 regardless of comorbidities
2) BMI over 35 w/ comorbidities When drug therapy was unsuccessful |
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Tx for Obesity after diet and exercise fail
|
Orlistat
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Dx Nausea and vomiting within months of bariatric surgery
|
Stomal stenosis
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Mgmt Unintentional weight loss with negative labs and imaging
|
Recheck in 6 months
(risk of ca low) |
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Most common cause of unintentional weight loss in ca negative patients
|
Depression
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Medication that can cause weight loss
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Bupropion
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Dx Unintentional weight loss, skeletal muscle dysfunction, osteoperosis, depression
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COPD
|
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Tx for Menorhagia
|
Medroxyprogesterone for 10-21 days
(Menoroghia is heavy menstrual bleeding) |
|
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Dx Oligomenorrhea, hirsutism, acne, alopecia
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PCOS
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Tx for Menopausal sx
|
Estrogen replacement therapy
|
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Dx study for Amenorrhea after pregnancy rule out
|
FSH, TSH, and Prolactin levels
|
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Dx study for Abnormal uterine bleeding in patients over 35
|
Endometrial biopsy
|
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Dx Well-demarcated, rapidly spreading area of warmth, swelling, tenderness, and erythema +/- fever
|
Cellulitis
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Dx Erythematous, dry or greasy scales and crusts
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Seborrheic dermatitis
|
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Dx Light pink to red papules and thin plaques with scaling, active borders and central clearing
|
Tinea
|
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Dx Erythematous macules and plaques that progress to epidermal necrosis and sloughing on less than 10% of body
|
Steven Johnson
|
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Dx Targetoid lesions of both skin and mucosal surfaces
|
Erythema multiforme
|
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Tx for Zoster reactivation
|
Oral antiviral if within 72 hours of onset of rash
|
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Dx Erythema, telangiectasias, papules, pustules, and sebaceous hyperlasia of the face and nasolabial folds
|
Rosacea
|
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Dx brown to black, well demarcated, stuck on papules
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Seborrheic keratoses
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Tx Extensive or inflammatory acne
|
Oral abx
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Dx Rapid appearance of wheal lasting less than 24 hrs
|
Acute uriticaria
|
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Mgmt Solitary, mobile, LAD of less than 2 cm
|
No mgmt needed
|
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Mgmt Enlarging, firm, axillary LAD in woman over 40
|
Biopsy
|
|
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Screening for hearing loss in elderly
|
Whispered voice test even if claiming asymptomatic
|
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Dx study for Fall in elderly patient
|
Get up and go test
|
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Tx Urge urinary incontinence
|
Tolterodine or Oxybutynin
|
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Mgmt of Non-specific dizziness in eldery patient
|
PT
|
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Initial Tx for Stage I HTN
|
Lifestyle modification for 6 to 12 months
(then you go to HCTZ) |
|
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Initial Tx for HTN in eldergy pt
|
HCTZ (more salt sensitive)
|
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BP Goal in diabetics or CKD
|
130/80
|
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Dx HTN, radial to femoral artery delay, rib notching
|
Coarctation of Aorta
|
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Initial Tx for Stage II HTN
|
2 drugs, usually HCTZ and ACE-I
|
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Dx Serum ferritin levels lower than 100-120
|
Iron deficiency anemia
|
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Dx Pancytopenia, low retic count, hypoplastic bone marrow (usually with fat)
|
Aplastic anemia
|
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Tx Iron deficiency anemia
|
Ferrous sulfate
|
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Dx bite or blister cells
|
G6PDase Deficiency
|
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Dx Low MCV and target cells with normal iron studies
|
Thalassemia minor
|
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Dx Macrocytic anemia, thrombocytopenia, elevated LDH
|
Vitamin B12 deficiency
|
|
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Dx study for suspected Vit B12 deficiency with low normal Vit B12
|
Methylmalonic acid and homocysteine
|
|
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Dx Elevated LDH, decreased serum haptoglobin, and elevated retic count
|
Hemolytic anemia
|
|
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Dx Hemolytic anemia, schistocytes, in setting of prosthetic valve
|
Prosthetic valve hemolytic anemia
|
|
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Dx Microcytic anemia, hypochromia, variable size, and variable shape
|
Iron deficiency anemia
|
|
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Dx Spherocytes on blood smear
|
Warm antibody-mediated hemolytic anemia
|
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Dx Long PT and PTT, high D-dimer, low serum fibrinogen and platelets, and microangiopathic hemolytic anemia
|
Disseminated intravascular coagulation
|
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Dx Long bleeding time, borderline PTT, low factor VIII wit FHx of coagulopathy
|
Von Willebrand
|
|
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Dx Transient aplastic crisis in patients with chronic hemolytic anemia (e.g. sickle cell disease)
|
Parvovirus
|
|
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Dx Right sided heart failure in sickle cell anemia
|
Pulmonary HTN
(common in sickle cell anemia) |
|
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Tx Acute chest syndrome in sickle cell anemia
|
Transfusion
|
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Dx study Osteonecrosis
|
MRI of the hip
|
|
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Dx study for Sickle cell anemia
|
Blood smear
|
|
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Dx Decreased platelets, thrombotic event in setting of recent heparin
|
Heparin induced thrombocytopenia and thrombosis
|
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Dx Microangiopathic hemolytic anemia, thrombocytopenia with normal coagulation, CNS sx, renal failure, fever
|
Thrombotic thrombocytopenic purpura
|
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Dx Large platelet clumps on stained blood film
|
Pseudothrombocytopenia
|
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Tx for Immune thrombocytopenic purpura
|
Corticosteroids
|
|
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Tx for Antiphospholipid syndrome after thrombus
|
Warfarin for life
|
|
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Dx Lupus anti-coagulant or anticardiolipin or B2 glycoprotein antibodies
|
Antiphospholipid
|
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Dx decreased AG with anemia, proteinuria, hypercalcemia, and renal failure
|
Multiple myeloma
|
|
|
Dx hypercalcemia, osteopenia, anemia, leukopenia, and renal insufficiency
|
Multiple myeloma
|
|
|
Dx M spike less than 3.0 with less than 10% plasma cells in bone marrow
|
Monoclonal gammopathy of unknown significance
|
|
|
Auer Rods
|
AML
|
|
|
Dx BCR/ABL oncogene, granulocytes with left shift, and myeloid proliferation in bone marrow
|
CML
|
|
|
Dx Blanching rythematous macules around wrists and ankles after tick exposure
|
Rock mountain spotted fever
|
|
|
Dx Very high or brief fever spikes and rapid defervescence without chills
|
Factitious fever
|
|
|
Dx Fever after inhaled anesthetics and depolarizing muscle relaxants
|
Malignant hyperthermia
|
|
|
Tx for Sepsis with hemodynamic instability
|
Fluids
|
|
|
Flu vaccine recommendations for COPD
|
Annually regardless of age for everyone with COPD
|
|
|
Dx Low MCV, low serum Fe, elevated TIBC, and low transferrin saturation
|
Iron deficiency anemia
|
|
|
Tx Rocky Mountain Spotted Fever
|
Doxycycline
|
|
|
Indication for Norepinephrine in septic shock
|
If MAP is less than 65 after fluid resuscitation
|
|
|
Criteria for Sepsis
|
1) Positive BCx or visible infxn
2) Systemic response to infxn, at least 2: fever, tachycardia, tachypnea, leukocytosis aka SIRS with positive BCx |
|
|
Criteria for Systemic inflammatory response syndrome (SIRS)
|
At least 2 of:
Fever HR over 90 Respiration greater than 20 (or PCO2 less than 32) Leukocytosis (or Immature bands 10%) |
|
|
Criteria for Septic shock
|
Sepsis with hypotension or evidence of perfusion abnormalities with adequate fluid resuscitation (or on vasopressors)
|
|
|
Severe complications of Group A Strep (3)
|
1) Peritonsillar abscess (quinsy)
2) Post-streptococcal glomerulonephritis 3) Rheumatic fever |
|
|
Tx for Acute otitis media
|
Amoxicillin
(Amox-clav or Ceftriaxone if not improved within 3 days) |
|
|
Centor Criteria for Strep Throat (4)
|
1) Fever
2) Tonsillar exudates 3) Tender LAD cervical 4) Absence of cough |
|
|
Mgmt according to Centor Criteria
|
0-1 Nothing
2-3 Rapid strep antigen test 4 Empiric Abx tx |
|
|
Mgmt for Asymptomatic UTI in pregnant woman
|
Ampicillin
|
|
|
Dx
Prostatitis refractory to Abx |
Prostatic abscess
|
|
|
Tx
Asymptomatic UTI |
No treatment
|
|
|
Dx
Fever, chills, sweats, n/v, diarrhea, and flank pain |
Pyelonephritis
|
|
|
Tx
Pyeloneophritis in non-pregnant woman |
Oral Fluoroquinolone
|
|
|
Tx
Recurrent UTI in healthy women |
Trimethoprim sulfamethoxazole (bactrim) PRN for days with symptoms
|
|
|
Dx
Mucoprurulent discharge or bleeding of os |
Cervicitis
|
|
|
Tx
Cervicitis |
Ceftriaxone with doxy or azithromcyin
|
|
|
Dx
Arthritis, tenosynovitis, sparese peripheral necrotic pustulues |
Gonorrhea
|
|
|
Dx
Fever, HA, and painful, ulcerated vesicular lesions on junk |
Genital herpes
|
|
|
Tx
Pelvic inflammatory disease |
Ceftriaxone and oral doxycycline
|
|
|
Dx
CD4 less than 200, fever, dry cough, dyspnea for several days or weeks |
Pneumocystis jirovecii
|
|
|
Tx
Pneumocystis jirovecii |
Bactrim
and Steroids if hypoxic |
|
|
HIV Abx prophylaxis by CD4 count and PPD
|
1) Less than 200 - Bactrim for PJP and Toxo
2) Less than 50 - Azithromcyin for Mycobacterium Avium 3) PPD positive but lungs clear - Isoniazid |
|
|
Dx study for
Acute HIV infxn |
RNA viral load
|
|
|
Dx
Ring enhancing lessions on MRI, neurologic deficits, in setting of HIV |
Toxoplasmosis
|
|
|
How to reduce ventilator associated PNA
|
Semi erect positioning of patient
|
|
|
Infectious precautions for C Diff
|
Barrier protection and soap and water
|
|
|
Precautions for Meningoccocal meningitis
|
Droplet precautions (surgical mask)
|
|
|
Precautions for TB
|
Airborne N95 mask
|
|
|
Mgmt for
Positive PPD |
CXR
|
|
|
PPD cutoffs by risk (3)
|
5 mm Immunosuppressed or highest risk (close contact with TB)
10 mm Immigration form endemic country or prison worker 15 mm for healthy people |
|
|
What must you get tested before starting a TNF-alpha inhibitor
|
TB tested with PPD (and treat if more than 5 mm)
|
|
|
Dx
Severe, progressive PNA during flu season |
MRSA
|
|
|
Tx
Community acquired PNA |
Azithromycin
|
|
|
Tx
PE from valve endocarditis (Right heart valve) |
Vancomycin plus cefepime
|
|
|
Tx
Left sided native endocarditis |
Penicillin plus gentamycin
or Ceftriaxone plus gentamycin |
|
|
Dx
Positive BCx, vegetation on Echo, and new valvular regurg |
Endocarditis
|
|
|
Dx study for
Suspected Vertebral osteomyelitis |
Spine MRI
|
|
|
Dx study for
Osteomyelitis |
MRI
|
|
|
Dx study for
Confirmed Osteomyelitis |
BCx or Bone culture
|
|
|
Pneumovax is indicated in everyone after their 65th birthday or after 65 if there have been more than 5 years since last vaccine
|
.
|
|
|
Dx
Severe, progressive PNA during flu season |
MRSA
|
|
|
Tx
Community acquired PNA |
Azithromycin
|
|
|
Tx
PE from valve endocarditis (Right heart valve) |
Vancomycin plus cefepime
|
|
|
Tx
Left sided native endocarditis |
Penicillin plus gentamycin
or Ceftriaxone plus gentamycin |
|
|
Dx
Positive BCx, vegetation on Echo, and new valvular regurg |
Endocarditis
|
|
|
Dx study for
Suspected Vertebral osteomyelitis |
Spine MRI
|
|
|
Dx study for
Osteomyelitis |
MRI
|
|
|
Dx study for
Confirmed Osteomyelitis |
BCx or Bone culture
|
|
|
Dx
Confusion and agitation in setting of chronic dementia with recent anesthesia |
Postooperative delirium
|
|
|
Tx
Acute delirium inpatient |
Haloperidol
|
|
|
Dx
Mental status changes, nystagmus, ophthalmoplegia, unsteady gait |
Wernicke's encephalopathy
|
|
|
Tx
Wernicke's encephalopathy |
Thiamine
|
|
|
Dx
Smudge cells |
CML
|
|
|
Dx
Proteinuria during day but not over night |
Orthostatic proteinuria
|
|
|
Dx
AKI with sterile pyuria (PMNs in urine) and WBC casts |
AIN
|
|
|
Dx study for
Persistent hematuria of non glomerular origin |
Cytoscopy
|
|
|
Dx
Muscle pain, weakness, dark urine, elevated serum creatine kinase |
Rhabdomyolysis
|
|
|
Dx
AKI, thrombocytopenia, microangiopathic hemolytic anemia |
Hemolytic uremic syndrome
|
|
|
Dx
Muddy brown casts in setting of drugs or prolonged renal ischemia |
ATN
|
|
|
Tx for
Diabetic nephropathy |
ACE-Is or ARBs
|
|
|
Indications for dialysis in CKD (4)
|
1) Hypervolemic
2) Hyperkalemic 3) Acidemic 4) Uremic |
|
|
Dx
Proteinuria, HTN, and decreasing GFR |
Diabetic nephropathy
|
|
|
Dx study for
AKI with suprapubic tenderness |
Renal US
|
|
|
Dx study for
Non diabetic nephropahty (hematuria) in a diabetic |
Renal biopsy
|
|
|
Dx
Bone disease, elevated PTH, hypocalcemic, and hyperphosphatemic |
Bone disease 2/2 hyperparathyroidism in CKD
|
|
|
What does the Urine anion gap (UAG) tell you? (3)
|
If negative - Extra renal metabolic acidosis
If positive (30-50) - Normal If positive in setting of metabolic acidosis - RTA |
|
|
Formula for Serum osmolality
|
= Na*2 + BUN/2.8 + gluc/18
|
|
|
Dx
Hypokalemia with low urine K |
Extra renal losses of K (laxatives or diarrhea)
|
|
|
Dx
Hypocalcemia in setting of acute pancreatitis |
Free fatty acid chelation of Ca
|
|
|
Tx for
Hypercalcemia in Sarcoidosis |
Corticosteroids (prednisone)
(decrease macrophages which produce 1alpha-hydroxylase which increases vit D) |
|
|
Most common cause of hypercalcemia outpatient
|
Hyperparathyroidism
|
|
|
Dx
Severe muscle weakness following glucose therapy in alcoholic |
Hypophosphatemia
(Insulin release from glucose moves phosphate into cells which is low bc of low oral intake) |
|
|
Risk for demented patients during surgery
|
General anesthesia
|
|
|
Tx for
Delirium inpatient |
Haloperidol
|
|
|
Dx
MS changes, ophthalmoplegia, nystagmus and unsteady gait |
Wernicke's encephalopathy
|
|
|
Cause of wenicke's encephalopathy
|
Thiamine deficiency
|
|
|
Dx
Neurologic sx including vision loss, hallucinations, numbness, tingling, weakness or confusion prior to HA |
Migraine with aura
|
|
|
Dx
Dull, bilateral, diffuse headache described as squeezing |
Tension type headache
|
|
|
Dx study
For sudden worst HA of life |
Non contrast Head CT
|
|
|
Tx for
Migraine prophylaxis (indication more than 2 per week) |
Amitrptyine (TCAs), Beta blockers, CCBs, valproic acid, topirmarate
|
|
|
Abortive Tx for Migraine
|
Triptans (5-HT1 agonists), NSAIDs, Ergotamine
|
|
|
Dx
Prominent memory loss, anomia, impaired recognition of illness, variable degree of personality change |
Alzheimers
|
|
|
Dx
Dementia of a few month onset with startle myoclonus |
Creutzfeldt-Jakob
|
|
|
Dx
Parkinsonism, visual hallucinations, fluctuating symptoms, impaired learning and attention, less memory impairment |
Dementia with Lewy bodies
|
|
|
Tx for
Mild Alzheimer's |
Donepezil
(ACh esterase inhibitor) |
|
|
Tx for
Moderate or advanced Alzheimer's |
Memantine
|
|
|
Dx
Resting tremor, bradykinesia, rigidity, postural instability |
Parkinson Disease
|
|
|
Dx
Tremor with voluntary movement that resolves with alcohol |
Essential tremor
|
|
|
Tx for
Essential tremor |
Propanolol
|
|
|
Dx
Meningitis with Gram positive bacilli in immunocompromised |
Listeria monocytogenes
|
|
|
Dx
Fever, HA, myalgia, purpuric rash that begins on wrists and ankles and spreads centripetally |
Rocky mountain spotted fever
|
|
|
Dx
Bacterial meningitis with Gram negative cocci |
Nisseria meningitidis
|
|
|
Empiric Tx for bacterial meningitis in patients over 50
|
Ceftriaxone + Vancomycin + Ampicillin
|
|
|
Empiric Tx for bacterial meningitis in patients under 50
|
Ceftriaxone + Vancomycin
|
|
|
When should rehab begin after stroke?
|
Immediately
|
|
|
Tx for
Acute Stroke within 3 hrs of onset |
tPA
Hold ASA until 24 hours after tPA |
|
|
BP cutoffs to treat HTN in post ischemic stroke
|
Over 220/120
|
|
|
Dx study for
Sudden worst HA of life with negative non contrast Head CT |
LP
|
|
|
Agent in Bell's palsy
|
HSV-1
|
|
|
Dx
Rapidly progressive Ascending extremity weakness, paresthesias, and areflexia. |
Guillaain-Barre
|
|
|
Dx
Wrist pain sparing palm, numbness and tingling in the median nerve distribution, weakness of thenar muscles |
Carpal tunnel
|
|
|
Dx
Stocking glove paresthesias or painful dysesthesias |
Diabetic neuropathy
|
|
|
Positive Finkelstein test
|
de Quervain tenosynovitis
|
|
|
Dx study for
New small breast mass on mammography |
Ultrasound
|
|
|
Dx
Persistent, scaling, eczematous, ulcerated lesion on breast around nipple |
Paget disease of breast
(indicates invasive or intraductal cancer) |
|
|
Dx study for
New breast mass |
Palpation, Mammography, and FNA
|
|
|
Tx for
Small focal breast cancer tumor (3) |
Lumpectomy
Sentinel node dissection Radiation |
|
|
Colonoscopy screening for 1st degree relative
|
1) Starting at 40 or 10 years before relative
2) Every 5 years |
|
|
Dx study for
Single positive FOBT in asymptomatic pt |
Colonoscopy
|
|
|
Screening for colon ca in IBD
|
1) Starting 8 years after onset of disease
2) Every year |
|
|
Dx screening for lung ca
|
None
|
|
|
Dx study for
Pulmonary nodule less than 4 mm in low risk population |
No study necessary
|
|
|
Dx study for
Diagnosed lung cancer |
Lymph node biopsy for staging
|
|
|
Tx for
Small cell lung cancer |
Chemotherapy and radiation
(surgery is not effective) |
|
|
Indications for prostate biopsy (2)
|
1) PSA over 4
2) Rising PSA |
|
|
Tx for
Prostate ca |
Leuprolide
|
|
|
Dx study for
Atypical pap smear results |
Colposcopy with biopsy
|
|
|
HPV vaccination recommendations
|
Females and males 9-26
|
|
|
Pap screening recommendations
|
1) Start at 21 or 3 years after first sex
2) Annually for 21-30 3) Every 3 years after if normal in 30-65 |
|
|
Dx
Berry like lesion |
Nodular melanoma
|
|
|
Hyperkeratotic precursor to squamous cell carcinoma
|
Actinic keratosis
|
|
|
Dx
Pink, pearly, nodules with telangiectasias |
Basal Cell carcinoma
|
|
|
Dx
Rapidly progressive, crater like firm nodule |
Keratoacanthoma
|
|
|
Tx for
Keratoacanthoma |
Surgical excision
(can cause tissue damage or become malignant) |
|
|
How to treat cancer pain
|
1) Non narcotics
2) Short acting narcotics 3) Then from that determine there long acting narcotic needs and Rx short acting for break through pain |
|
|
Tx for
Dyspnea in hospice ca care |
Opioids (short acting)
|
|
|
Definition of unstable angina
|
Angina is new, worsening, or occurring at rest
|
|
|
Antihypertensive for a diabetic patient with proteinuria
|
ACE-I
|
|
|
Dx
Hypotension, distant heart sounds, JVD |
Cardiac tamponade
|
|
|
Drugs that slow AV node conduction (3)
|
1) Beta blockers
2) Digoxin 3) CCBs |
|
|
HOCM murmur
|
Systolic ejection murmur along lateral sternal border that increases with Valsalva maneuver and standing
|
|
|
Murmur aortic insufficiency
|
Diastolic, decrescendo, high pitched, blowing murmur best heard when standing up
|
|
|
Murmur aortic stenosis
|
Systolic crescendo/decrescendo murmur that radiates to the neck, increases with increased preload
|
|
|
Murmur mitral regurg
|
Holosystolic murmur that radiates to the axilla or carotids
|
|
|
Murmur mitral stenosis
|
Diastolic, mild to late, low pitched rumble
|
|
|
Tx for
Afib or Aflutter 1) If unstable 2) If stable |
1) If unstable - Cardiovert
2) If stable - Rate control with Beta blockers |
|
|
Tx for
Vfib |
Cardioversion
|
|
|
Autoimmune complication 2-4 weeks post MI
|
Dressler's syndrome: fever, pericarditis, elevated ESR
|
|
|
Tx for
IV drug use with JVD and holosystolic murmur at left sternal border |
Treat existing HF and replace tricuspid valve
|
|
|
Dx study for
Hypertrophic cardiomyopathy |
Echo
|
|
|
Dx
Fall in systolic BP greater than 10 mm with inspiration |
Pulsus parodoxus --> Cardaic tamponade
|
|
|
Classic EKG findings in pericarditis (2)
|
1) Low voltage
2) Diffuse ST segment elevation |
|
|
Indications for surgical repair of AAA
|
Greater than 5.5 cm
Rapidly enlarging Symptomatic or Ruptured |
|
|
EKG findings in MI (3)
|
1) ST segment elevations
2) Flattened T waves 3) Q waves |
|
|
Dx
Young patient with angina at rest, ST segment elevation, nl cardiac enzymes |
Prinzmetal's angina
|
|
|
Dx
CHF, shock, altered MS |
Silent MI
|
|
|
Agent that reverses effect of heparin
|
Protamine
|
|
|
Endocarditis prophylaxis
1) Dental 2) GI or GU surgery |
1) Dental - Amoxicillin
2) GI or GU surgery - Ampicillin + Gentamicin |
|
|
Most common cause of HTN in young women
|
OCPs
|
|
|
Most common cause of HTN in young men
|
EtOH
|
|
|
Asplenic patients are susceptible to these organisms
|
Encapsulated organisms
1) Strep pneumo 2) Nisseria meningitidis 3) H flu 4) Klebsiella |
|
|
Number of bac needed on urine sample to think UTI
|
100,000
(100k) |
|
|
Dx
Fever, malaise, cough, night sweats recent SW US travel. Tx? |
Dx - Cocciodomycosis
Tx - Amphotericin B |
|
|
Dx
Blueberry muffin rash |
Rubella
|
|
|
What should always be done before LP?
|
Check ICP with papilledema or head CT
|
|
|
Dx
Gamma globulins in CSF |
Multiple sclerosis
|
|
|
Dx
Initial pruritic papule with LAD progresses to eschar in 7-10 days Tx? |
Dx - Cutaneous anthrax
Tx - Penicillin or Ciprofloxacin |
|
|
Dx
Tabes Dorsalis, general paresis, gummas, argyll robertson pupils, aortitis, aortic root aneurysm |
Tertiary syphilis
|
|
|
Dx
Arthralgia, migratory polyarthropathies, Bell's palsy, myocarditis |
Secondary Lyme disease
|
|
|
Dx
Cold agglutinins |
Mycoplasma
|
|
|
Tx for
Candidal thrush |
Nystatin oral suppression
|
|
|
When and what to begin in HIV opportunistic prophylaxis
|
1) Less than 200 CD 4 count - Bactrim for Pneumocystis jiroveci
2) Less than 100 - Clarithromycin/Azithromycin for MAI |
|
|
Dx
Alcoholic and smoker with lung sx with no gram stain but positive silver stain |
Legionella pneumonia
|
|
|
Dx
Acute onset monoarticular joint pain, bilateral bell's palsy. Tx? |
Dx - Lyme disease
Tx - Doxycycline |
|
|
Main organisms in endocarditis (2)
|
1) Stapy aureus
2) Strep epidermidis |
|
|
Dx
Branching rods in oral infection |
Actinomyces israelii
|
|
|
Dx
Painful chancroid |
Haemophilus ducreyi
|
|
|
Dx
Dog or cat bite |
Pasteurella
|
|
|
Dx
Infection in gardner |
Sporothrix (sporotrichosis)
|
|
|
Dx
Infxn pregnant with pets |
Toxoplasmosis
|
|
|
Dx
Meningitis in adults |
Neisseria meningitidis
|
|
|
Dx
Meningitis in elderly |
Strep pneumo
|
|
|
Dx
Alcoholic with pneumonia |
Klebsiella
|
|
|
Dx
Currant Jelly sputum |
Klebsiella
|
|
|
Dx
Infxn in burn victims |
Pseudomonas
|
|
|
Dx
Osteomyelitis from foot wound puncture |
Psuedomonas
|
|
|
Dx
Osteomyelitis in sickle cell patient |
Salmonella
|
|
|
Dx
HTN with hypokalemia 1) If renin activity low 2) If renin activity high |
1) If renin activity low - Primary Hyperaldosteronism
2) If renin activity high - Renovascular HTN (renal artery stenosis) |
|
|
Dx
Purpura in elderly on back of hands Tx? |
Perivascular connective tissue atrophy
Tx - none |
|
|
Dx
Palpable purpura, low complement levels, glomerulonephritis, arthralgias, hepatosplenomegaly, |
Mixed Essential Cyroglobulinemia
|
|
|
Dx
Muscle weakness (extreme) that resolves with rest |
Myasthenia gravis
|
|
|
Tx for
Benign essential tremor |
Propanolol
|
|
|
Dx
Tremor with planned, voluntary movement only, family hx |
Essential tremor
|
|
|
The 4 criteria of Nephrotic Sx
|
1) Proteinuria greater than 3 g/day
2) Hypoalbuminemia (less than 3.5) 3) Edema 4) HLD and lipiduria (waxy casts) 3) |
|
|
What kind of state is nephrotic sx?
|
Hypercoagulable
|
|
|
Pharmacologic agents that shift K into cells in acute hyperkalemia
|
1) Insulin and glucose
2) Na bicarb 3) Beta 2 agonists |
|
|
Dx
Nephrotic sx in Blacks with obesity, heroin, or HIV hx |
Focal Segmental Glomerulosclerosis
|
|
|
Most common cause of nephrotic sx in adults
|
Membranous nephropathy
|
|
|
Most common cause of nephrotic sx in children
|
Minimal change disease
|
|
|
Dx
Lung and GI involvement in immunocompromised pt |
CMV
|
|
|
Dx
Fever, hives, arthralgias, and LAD after infection (usually 7-10 days later) |
Drug induced reaction (serum sickness)
|
|
|
Dx
New clubbing in COPD pt |
Lung cancer
|
|
|
Dx
Recurrent pain, itching, and red steaks in arms in setting of weight loss |
Trousseau's syndrome (migratory thrombophlebitis) caused by occult malignancy usually pancreatic or lung)
|
|
|
Dx
New HA, jaw pain, scalp pain, visual loss. |
Temporal arteritis
|
|
|
Tx for
Temporal arteritis |
High dose prednisone
(to prevent damage to retinal artery and other vessels) |
|
|
Dx
Weakness, fatigue, hypotension, cold intolerance, brittle nails, bradycardia |
Pituitary tumor causing secondary adrenocortical deficiency
|
|
|
Dx
Hyperpigmentation, amenorrhea in young adult |
Congenital adrenal hyperplasia
|
|
|
Most common deficiency in Congential adrenal hyperplasia
|
21-hydroxylase deficiency
|
|
|
Dx study for
CP in young woman with no risk factors for CAD |
None
|
|
|
Dx study for
Newly diagnosed Myasthenia gravis |
Chest CT (to look for thymoma)
|
|
|
Tx for
Kidney stones in acidic urine |
Potassium citrate
|
|
|
Dx
Palpable mass in RUQ with hyperbilirubinemia in child |
Choledochal cyst
|
|
|
Tx for
Cocaine induced CP |
Benzos
(also nitrates and aspirin) |
|
|
Dx
Epigastric pain with voluminous pale foul smelling diarrhea |
Chronic pancreatitis
|
|
|
Dx
EKG shows flat and broad T waves, PVCs |
Hypokalemia
|
|
|
Dx
Fever, ns, LAD, arthralgias, diarrhea |
Acute HIV
|
|
|
Dx
New onset diabetes, arthropathy, and hepatomegaly |
Hemochromatosis
|
|
|
Dx
No pulses but telemetry shows beats |
Pulseless electrical activity (PEA)
|
|
|
Tx for
PEA (pulseless electrical activity) |
Chest compressions, ventilation with 100% oxygen
|
|
|
Door to therapy time for PCTA and fibrinolysis in MI
|
PTCA - 90 minutes
Fibrinolysis - 30 minutes |
|
|
Most common cause of uncomplicated UTI in women
|
Ascending infection of urethra usually from sex (honeymoon cystitis)
|
|
|
Dx
Hazy lung fields, cough, dyspnea, fever, malaise in setting of farming or bird care |
Hypersenstivity pneumonitis (bird fancier's lung or famer's lung)
|
|
|
Tx for
Hypersensitivity pneumonitis |
Avoidance of antigen
|
|
|
Dx
Arthritis, lesions on shins, bloody diarrhea, P-ANCA positive |
UC (IBD)
|
|
|
Ankylosing spondylitis and Ulcerative colitis share this HLA type
|
HLA-B27
|
|
|
Most common sites of thrombus for PE
|
1) Iliac
2) Femoral 3) Popliteal |
|
|
Dx
Elevated alk phos and bowed legs on xray |
Paget's disease
|
|
|
Dx
RUQ pain, mildly elevated liver enzymes, firm hepatomegaly. |
Mets to the liver (usually from GI)
|
|
|
Dx
High fever, chills, tenosynovitis, migratory polyarthralgias and pustular lesions on extremities, negative BCx |
Disseminated gonococcus
|
|
|
Dx
4th and 5th finger decreased sensation and weakened grip |
Ulnar nerve syndrome
(medial elbow compression) |
|
|
Dx
Heel pain, +/- shoulder, hip, and shin pain |
Enthesitis due to Ankylosing spondylitis
|
|
|
Blood lab findings in Vit D malabsorption (3)
|
1) V. Low phosphate
2) Low Ca 3) High PTH |
|
|
Which vitamin increases INR
|
Vitamin E
|
|
|
Dx
High Ca, low Phosphate, abdominal pain, constipation, fatigue, excessive urination, urinary stones |
Hyperparathyroidism
|
|
|
Hyperparathyroidism predisposes to what arthralgia?
|
Pseudogout
|
|
|
Which joint does pseudogout usually affect
|
Knee
|
|
|
Dx
Intermittent abdominal distension, flatulence, greasy stools, iron deficiency anemia |
Celiac sprue
|
|
|
Skin condition associated with celiac sprue
|
Dermatitis herpetiform
|
|
|
Dx study for
BRBPR under 50 with no risk factors for colon cancer |
Anoscopy
|
|
|
Most common causes of osteomyelitis in sicke cell (2)
|
1) Salmonella
2) Staph |
|
|
Dx
Smudge cells |
CLL
|
|
|
Dx
Cause of erectile dysfunction following urethral surgery |
Neurogenic
|
|
|
Mechanism of fatty liver
|
Insulin resistance increases lipolysis leading to fat accumulation in hepatocytes
|
|
|
Dx
High PaCO2 and low PaO2 |
Alveolar hypoventilation
|
|
|
Dx
COPD with sudden onset of catastrophic worsening of respiratory sx |
Pneumothorax (dilated alveolar blebs rupture in the pleural space)
|
|
|
Most common cause of osteomyelitis in children
|
Staph aureus
|
|
|
Dx
Air fluid levels in the gall bladder in elderly diabetic male |
Emphysematous cholecystitis
|
|
|
Dx
Slow onset hazy visual loss |
Cataracts
|
|
|
Dx
Focal site of increased radio active iodine uptake with otherwise decreased uptake in the thyroid |
Toxic nodule
|
|
|
Dx
HAs worse in morning, n/v early in day, vision changes, somnolence, confusion, hypertension and bradycardia |
Increase intracranial pressure
|
|
|
Dx
Bilateral lower extremity weakness following termporal arteritis tx |
Steroid induced myopathy
|
|
|
Dx study for
New onset dyspepsia in 1) Over 55 2) Alarm sx of weight loss, dysphagia, vomiting 3) All others |
1) Upper endoscopy
2) Upper endoscopy 3) PPI or H Pylori serology |
|
|
Dx
Insidious onset dry cough in absence of constitutional sx, also with skin lesions and uveitis in african american women |
Sarcoid
|
|
|
Dx
Lower leg discomfort at night relieved by massage or movement of them |
Restless leg syndrome
|
|
|
Tx for
Restless leg syndrome |
Dopamine agonists
|
|
|
Dx study for
Adult with recurrent bacterial infections |
Serum Ig levels to consider humoral immunity deficiency
|
|
|
Dx study for
Cancer patient with back pain and neurologic sx particularly bowel or bladder incontinence |
MRI of spine
|
|
|
Tx for
Cancer patient with back pain and neurologic sx particularly bowel or bladder incontinence |
Dexamethasone to decrease swelling on spine
(while awaiting MRI results) |
|
|
Tx for
Lactic acidosis from septic shock (3) |
1) Fluids
2) Vasopressors if necessary 3) Abx |
|
|
In patients refractory to HTN tx always treat their lifestyle problems before adding more therapeutics
|
.
|
|
|
Dx
HA, n/v with enclosed air space occupation |
Carbon monoxide poisoning
|
|
|
Dx study for
Elderly pt with new onset delirium |
Urinalysis and electrolytes
|
|
|
Dx
Elderly male with dysphagia, regurgitation, foul-smelling breath, aspiration, possibly palpable mass |
Zenker's diverticulum
|
|
|
Dx
Chest scan showing primary nodules with a halo sign |
Aspergillosis
|
|
|
Dx
Acute pneumonia, cough, fever malaise, hilar lymphadenopathy on CXR, recent travel to Southeastern, mid Atlantic, and central US |
Histoplasmosis
|
|
|
Dx
Pneunomia with arthralgias recent travel to SW US |
Coccidio
|
|
|
Dx
Liver cysts with multiple cysts inside of the cysts. What exposure? |
Hydatid cysts from Echinococcosis.
Sheep exposure |
|
|
Dx
Right sided effusion with cirrhosis |
Hepatic hydrothorax
|
|
|
Tx for
Hepatic hydrothorax |
Tx Thoracentesis and diuretics
If refractory, TIPS |
|
|
Common drugs that cause hyperkalemia
|
1) ACE-Is
2) NSAIDs 3) K sparing diuretics (spironolactone and amiloride) |
|
|
Dx
Hematemesis following multiple episodes of non-bloody vomiting |
Mallory Weiss tear (ruptured submucosal arteries of distal esophagus)
|
|
|
Which HepB serology is most useful to determine acute Hep B infection? (2)
|
ABsAg and anti-HBc antibody
|
|
|
Dx
Corneal vesicles and dendritic ulcers |
Herpes simplex keratitis
|
|
|
Mgmt
New onset lupus |
Get kidney biopsy then start methylprednisone
|
|
|
Dx
Verrucuous, skin colored or pink papules around anus |
Anogenital warts (HPV)
|
|
|
Tx for
Anogenital warts (HPV) |
Podophyllin
|
|
|
Tx for
Prolactinoma |
Dopamine agonists (bromocriptine or cabergoline)
|
|
|
Mgmt
GERD with dysphagia, weight loss, odynophagia |
Upper endoscopy
|
|
|
Prophylaxis for MAC when CD 4 count less than 50
|
Azithromycin for Mycobacterium avium complex
|
|
|
Most common type of thyroid malignancy
|
Papillary carcinoma of the thyroid
|
|
|
Dx
Normocytic anemia, hypercalcemia, renal failure, elevated total protein |
Multiple myeloma
|
|
|
Dx study for
Multiple myeloma |
Serum immunoelectrophoresis
|
|
|
Which compound is increased in androgen producing adrenal tumors?
|
DHEA
|
|
|
Dx
FEV1/FVC ratio decreased and normal DLCO |
Bronchitis
|
|
|
Potential fatal side effect of succinylcholine
|
Hyperkalemia
|
|
|
Dx
Ca low and Phos low |
Vit D deficiency
|
|
|
Dx
Ca low but Phos high. 1) If If PTH v high 2) If PTH high 3) If PTH low |
1) If If PTH v high - Pseudohypoparathyroidism
2) If PTH high - Renal failure 3) If PTH low - Hypoparathyroidism |
|
|
Pronator drift localizes the lesion to where?
|
Upper motor neuron
|
|
|
What happens to Ca in alkalemia
|
It binds better to albumin causing effective hypocalcemia despite normal total serum Ca levels
|
|
|
Dx
Post partum woman fails to lactate with pituitary hormonal deficiency |
Sheehan's syndrome (ischemic necrosis of pituitary gland following shock from childbirth)
|
|
|
Dx
Tender regional LAD, following cat laceration |
Azithromycin for cat scratch disease (bartonella)
|
|
|
Dx
Hypercalcemia, constipation, abdominal pain, weight loss, polyuria, polydipsia |
Vit D toxicity
|
|
|
Dx
Pruritic, papules and plaques on face, scalp, chest, and extensor surface of baby sparing diaper area |
Atopic dermatitis
|
|
|
Dx
Very high Ca, low PTH, high Phosphate |
Hypercalcemia of malignancy
|
|
|
Dx study for
Curtain drop loss of vision |
Dx is amaurosis fugax and is usually caused by carotid embolization.
Get carotid artery doppler. |
|
|
Dx
Ring shaped scaly patch with central clearing and distinct border Tx? |
Dx - Tinea corporis
Tx - Antifungal cream (e.g. terbinafine) |
|
|
Tx for
Myasthenia crisis |
Endotracheal intubation and withdrawal of anti-cholinesterases
|
|
|
Dx
Pneumonia with targetoid lesions on extremities |
Lesions are erythema multiform and the patient has mycoplasma pneumonia
|
|
|
Dx
Partially acid fast, filamentous, branching rods on sputum exam |
Nocardia
|
|
|
Mgmt for
Severe symptomatic hyponatremia. And what to watch out for... |
1) Hypertonic saline
2) Central pontine myelinosis from too rapid increase in serum osmolality |
|
|
Dx
What is low in macrocytic anemia when there is peripheral neuropathy? |
Cobalmin (Vit B12)
id est not Folate which can correct the anemia but not the neuropathy |
|
|
Dx
Progressive dyspnea and hypoxia in AIDS patient |
Pneumocystis jiroveci
|
|
|
Dx
Vertigo, tinnitus, vomiting, nystagmus |
Meniere's disease
|
|
|
Tx for
Meniere's disease |
Salt restriction and caffeine, nicotine, and alcohol avoidance
|
|
|
Dx
Loud S1 and mid diastolic rumble |
Mitral stenosis
|
|
|
Dx
Clotting history with lupus signs |
Antiphospholipid antibody sx (lupus anticoagulant positive which is actually a hypercoagulable state)
|
|
|
Dx study for
Lupus anticoagulant |
Russel viper venom test
|
|
|
Which way does PTT move in lupus anticoagulant
|
PTT increases (paradoxically bc hypercoagulable)
|
|
|
Drug whose side effect profile is
Nephrotoxicity, hyperkalemia, hypertension, gum hypertrophy, hirsutism |
Cyclosporine
|
|
|
Drug whose side effect profile is
Nephrotoxicity, hyperkalemia, hypertension, |
Tacrolimus
|
|
|
Drug whose side effect profile is diarrhea, leukopenia, hepatotoxicity
|
Azathioprine
|
|
|
Drug whose side effect profile is bone marrow suppression
|
Mycophenolate
|
|
|
Tx for
Aortic dissection |
Antihypertensives
|
|
|
Mgmt for
Targetoid lesions and malaise, HA, muscle pain, and joint pain |
Doxycycline for Lyme (not testing necessary)
|
|
|
Dx
Weight loss, gynecomastia, testicular atrophy, telangiectasias |
Chronic liver disease
(hyperestrogen state due to reduced clearance by ****** liver) |
|
|
Dx
Hx of sudden cardiac death with syncopal episodes and hearing impairment |
Long QT
|
|
|
Tx for
Long QT |
Beta blockers
|
|
|
Dx
Hypercalcemia and stomach ulcer |
Hyperparathyroidism and zollinger-ellison sx suggestive of MEN1
|
|
|
Diagnostic criteria for ARDS
|
1) Acute respiratory distress in setting of predisposing condition sepsis, pneumonia etc
2) Bilateral infiltrates 3) Normal PCWP |
|
|
Dx
Normal FEV1/FVC with decreased DLCO |
Interstitial lung disease
|
|
|
Clopidogreal indications post STEMI
|
1) Post UA/NSTEMI for 12 months
2) Post PCI 30 days for bare metal and 12 months for DES |
|
|
Dx
Contralateral half body pain and temperature loss with cranial nerve defect |
Lateral medulla
|
|
|
Dx
Contralateral half body paralysis and proprioception and vibratory loss |
Medial medulla
|
|
|
Dx study for
Cough, mucopurulent sputum, hemoptysis that responds to abx |
High resolution CT scan for Bronchiectasis
|
|
|
Terrible T's of anterior mediastinal mass (4)
|
1) Thymoma
2) Teratoma 3) Thyroid cancer 4) Terrible Lymphoma |
|
|
Dx
Anterior mediastinal mass with elevated alpha feto protein and elevated beta human chorionic gonadotropin |
Nonseminomatous germ cell tumor
|
|
|
Dx
Anterior mediastinal mass with elevated beta human chorionic gonadotropin |
Seminoma
|
|
|
Dx
Prolonged PT before a prolonged PTT |
Vit K deficiency
|
|
|
Dx
Grid test looks like curved lines |
Macular degeneration
|
|
|
Dx
Parkinson like rigidity, psychosis, hallucinations, confusions, REM disorder, parkinson sx worse with neuroleptic (anti-psychotics) |
Lewy body dementia
|
|
|
Dx
Early diastolic murmur |
Aortic regurg
|
|
|
DEXA screening recs
|
1) Women over 65
2) Women 60-64 if risk of fracture |
|
|
Yellow fever vaccine is for what countries
|
Sub saharan africa and S America
|
|
|
Vaccines in HIV
|
1) Tdap every 10 years
2) Pneumovax (revaccinate in 5 years) 3) Flu annually 4) Hep A and B 5) Meningococcus if asplenic or in college/military 6) HPV (only in high risk individuals) 7) H Flu (only if not given in infancy) 8) MMR and varicella if CD4 over 200 |
|
|
Recs for treated cervical neoplasia
|
1) Pap smear +/- colposcopy +/- curretage every 6 months until 3 negative results in a row
2) Then resume normal screening for age |
|
|
AAA rec
|
ULTRASOUND OF ABDOMEN in all men 65-75 who ever smoked
|
|
|
Pressure ulcer preventino
|
Repositioning every 2 hours
|
|
|
Mammography frequency
|
Every 2 years from 50-75 years old
|
|
|
Pneumovax recommendations
|
1) Everyone over 65
2) Adults under 65 with cardiovascular, pulmonary, hepatic, renal, diabetes, or immunosuppressin 2a) Under 65 need a booster over 65 |
|
|
When colonoscopy starts for 1st degree relative
|
10 years before their onset
|
|
|
Give hep B vaccine and Ig if exposed with no known immunization history
|
.
|
|
|
Vaccines for hepatic disease
|
1) Tdap
2) Flu 3) Pneumovax 4) Hep A and B |
|
|
Bladder cancer screening in at risk population
|
Not recommended ever
|
|
|
Dx
Onion skin appearance with moth eaten mottled appearance on bone xray |
Ewing's sarcoma
|
|
|
Which metal causes type IV hypersensitivity
|
Nickel
|
|
|
Auto-Antibodies in scleroderma (2)
|
1) Anti-Topoisomerase
2) ANA |
|
|
Mgmt for
Familial colonic polyposis |
Procto-colectomy
|
|
|
Dx
Hematuria, deafness, and fhx of renal failure |
Alport's syndrome
|
|
|
Pain mgmt in past drug abuser
|
Opioids (do not deny despite history)
|
|
|
Most common complication of PUD
|
Hemorrhage
|
|
|
Dx
Dysphagia, CP, food regurgitation, dilated esophagus, bird's beak deformity |
Achalasia
|
|
|
Dx
Normal Ca, normal alk phos, low phosphate, and normal vit D with rickets |
X-linked hypophosphatemic rickets
(phosphate wasting) |
|
|
Aphasia localized an infarct to where?
|
Cortex usually on the Left side (dominant side given R handed)
|
|
|
Dx
Back pain, anemia, renal dysfunction, elevatd ESR |
Multiple myeloma
|
|
|
Dx
High alk phos, normal liver tests, hearing loss |
Paget's disease
|
|
|
Dx
Intense, focal back pain without neurological symptoms not relieved by rest |
Vertebral compression
|
|
|
Dx
Apophyseal joint arthritis |
Ankylosing sponylitis
|
|
|
Dx
Intervertebral disc degereneration |
OA of the spine
|
|
|
Dx
Falling into chairs, can't raise arms above head, light tremors |
Hyperthyroid
|
|
|
Most common type of kidney stone
|
Calcium oxalate
|
|
|
Dx
Hip pain in setting of corticosteroids Mgmt? |
Avascular necrosis of femoral head
Mgmt - needs MRI |
|
|
Dx
Circumferential narrowing of distal esophagus with dysphagia |
Peptic stricture
|
|
|
Dietary recs for kidney stones (4)
|
1) decreased protein and oxalate
2) Decreased Na 3) Increased fluid 4) Increase Ca |
|
|
Dx
PAinful, rubbery nodule on eyelid Mgmt? |
Chalazion
Mgmt - Biopsy |
|
|
Dx
Mucoid, Gram negative rod |
Klebsiella
|
|
|
Dx
Weakness, weight loss, skin color changes |
Hemachromatosis
|
|
|
How to diagnose follicular cancer of thyroid from just adenoma
|
Invasion of capsule
|
|
|
Dx
Mucopurulent urethral discharge, no bacteria on culture |
Chlamydia
(think gonorrhea if purulent discharge) |
|
|
Dx
Hypersegmented neutrophil |
Megaloblastic anemia
|
|
|
Increased metabolite differences in Vit B12 and Folate deficinecy
|
Vit B 12 deficiency: Increased homocysteine AND methlymalonic acid
Folate deficiency: Just Homocysteine elevated |
|
|
Dx
Motor hemiparesis of face, arm, and leg without other neurologic deficits |
Internal capsule
|
|
|
Dx
Hemiplegia, aphasia, hemineglect |
Middle cerebral artery
|
|
|
Dx
Contralateral weakness of lower extremities mostly, emotional disturbance |
Anterior cerebral artery
|
|
|
Dx
Contralateral hemiplegia with Ispilateral cranial nerve involvement |
Vertebrobasilar system (brain stem)
|
|
|
Most likely cancer in asbestosis
|
Bronchogenic carcinoma
(Not mesothelioma!) |
|
|
Dx
Ascending paralysis, areflexia, 3-4 weeks after URI or gastroneteritis, CSF shows albumino-cytologic dissociation |
Guillan barre
|
|
|
Tx
Guillain Barre |
IV Immunoglobulins and plasmapharesis
|
|
|
Dx
Pruritis, tense bullae, uriticarial plaques, with IgG and C3 along basement membrane zone |
Bullous pemphigoid
|
|
|
Dx
Follicular conjunctivitis with neovascularization of conjunctiva |
Trachoma (chlamydia thrachomatis infection)
|
|
|
Side effect of Anti thyroid meds in grave's disease
|
Agranulocytosis and allergy
|
|
|
What causes orthostatic hypotension in elderly?
|
Decreased sensitivity of baroreceptors
|
|
|
Mgmt
AKI due to possible urinary retention |
Straight cath (not US for residual volume)
|
|
|
Mgmt
Esophagitis in HIV |
Fluconazole empiric tx for candidiasis
If refractory then upper endoscopy for CMV |
|
|
Mgmt
Solid testicular mass |
Radical removal of testis and cord
|
|
|
Prophylaxis for splenectomy
|
1) Pneumovax, h flu, meningococcus vaccines before surgery
2) Daily oral PCN for 3-5 years after |
|
|
Dx
Painless hematuria |
Bladder mass
|
|
|
People with hemachromatosis are suscpetible to what organism
|
Listeria
|
|
|
Dx
Progressive proximal weakness with elevated serum creatinine kinase |
Myositis and dermatomyositis
|
|
|
Tx for
Myositis |
Steroids
|
|
|
Tx for
Gastroparesis |
Metoclopramide (prokinetic)
|
|
|
Mgmt
Rapidly developing (over 3 months) male characteristics in woman |
Hormone producing tumor
Serum testosterone --> ovarian source Serum Testosterone and DHEAS --> Adrenal source |
|
|
Dx
Fever, rash, occipital or posterior cervical LAD, and arthritis |
Rubella
|
|
|
Findings in OA
|
1) Crepitus
2) Bony enlargment 3) Bony tenderness 4) Stiffness without warmth 5) Over 50 yo Need 3 for a diagnosis |
|
|
Strongest risk factor for stroke
|
HTN
then smoking and DM |
|
|
Traveler's diarrhea
|
E coli
|
|
|
Dx
Back pain on trauma with ankylosing spondylitis |
Vertebral fracture
|
|
|
Tx
Parkinson's |
Trihexyphenidyl
|
|
|
How to diagnose parkinson's
|
Physical exam:
Tremor Rigidity Bradykinesia |
|
|
Dx
HCG and AFP elevated |
Nonseminomatous tumor
|
|
|
Acute Migraine tx
|
Prochlorperazine, chlorpromazine, or metoclopramide
|
|
|
Auto antibody in Primary biliary sclerosis
|
Anti-mitochondrial Ab
|
|
|
Dx
Autoimmune destruction of intrahepatic bile ducts with cholestasis |
Primary biliary sclerosis
|
|
|
Lite's criteria for Exudate
|
1) Total protein ratio more than 0.5
2) LDH ratio more than 0.6 3) LDH greater than 2/3 of upper limit of normal |
|
|
Dx
Decreased breath sounds on left after intubation |
Accidental intubation of tight main stem bronchus
|
|
|
Renal complication of Hepatitis
|
Membranoproliferative glomerulonephritis
|
|
|
Causes of pulsus paradoxus (3)
|
1) Cardiac tamponade
2) Tension pneumothorax 3) Severe asthma |
|
|
Dx
Vertigo, vomiting, and occipital headache |
Cerebellar stroke
|
|
|
Mgmt
Hot potato voice and deviated uvula |
Aspiration of abscess
|
|
|
Dx
Large basophilic cells (atypical lymphocytes) with negative monospot |
CMV
|
|
|
Dx
Down and out eye with ptosis in diabetic |
Ischemic CNIII palsy
|
|
|
Mgmt
Pyelonephritis |
BCx Then empiric Abx then if refractory US
|
|
|
Dx
Wedge shaped consolidation on CT scan of lungs |
Pulmonary embolism
|
|
|
Respiratory monitoring in Guillain barre
|
Bedside Vital Capacity
|
|
|
Dx
40 yo male with back pain that is worse in morning and improves during the day |
Ankylosing spondylitis
|
|
|
Tx for
Acute cholangitis |
Supportive care and Abx
Then ERCP for biliary drainage and or to remove stone |
|
|
Dx
Chronic hematomas and joint swelling |
Hemophilia
|
|
|
Dehydration: Crystalloids or colloids
|
Crystalloids
|
|
|
Tx for
Cellulitis with systemic signs |
IV Nafcillin
|
|
|
Tx for
Multiple sclerosis |
Interferon-beta
|
|
|
Dx
Seizure without LOC or amnesia |
Simple partial seizure
|
|
|
Dx
Seizure with LOC, aura, and autamatisms |
Complex partial seizure
|
|
|
Dx
Seziure with LOC, tonic clonic activity |
Partial seizure with secondary generalization
|
|
|
Mgmt for
Cat bite |
Amox clav for pasteurella
|
|
|
Dx
Polyuria in sickle cell trait or disease |
Hyposthenuria
|
|
|
3 Mechanical complications post MI
|
1) MR due to papillary muscle rupture
2) LV free wall rupture 3) Interventricular septal rupture |
|
|
Dx
Hypothyroidism, HAs, bitemporal blindness |
Craniopharyngioma
|
|
|
Dx
ST elevation in II, III, and AVF |
Right Coronary Artery occlusion
|
|
|
There are no pathologic changes in IBD!!
|
!
|
|
|
PPD cutoffs
|
1) Healthy people: 15 mm
2) 10mm for immigrants, drug users, high risk employees, diabetics 3) 5 mm for HIV, recent exposure to TB, TB on CXR, immunosuppressed PTs |
|
|
Tx for
Latent TB |
Isoniazid for 6 months
|
|
|
Tx for
Active TB |
Iszoniazid, INH, rifampin, pyrazinamide for 8 weeks then 4 more months of isoniazid and rifampin
|
|
|
Essential tremor
|
Absent at rest but present with intentional movement
|
|
|
Tx for
Essential tremor |
Beta blockers
|
|
|
Urinary side effects of antihistamines
|
Anticholinergic effect causes detrussor inactivity
|
|
|
Tx for
Gastric MALT without metastases |
Triple H pylori regimen
(omeprazole, clarithromycin, and amoxicillin) |
|
|
Dx
Dyspnea, fatigue, and peripheral edema following viral infection |
Dilated cardiomyopathy due to viral myocarditis
|
|
|
Mgmt
For 1st degree heart block |
No tx
|
|
|
Dx
Medial knee pain without positive valgus stress test |
Anserine bursitis
|
|
|
Mgmt
Recurrent attcks of focal neurological sx at non predicatable intervals |
MRI for MS
|
|
|
Dx
Initial presentation of impaired gait, dementia, and urinary incontinence |
Normal pressure hydrocephalus
(Alzheimer's will have more memory and visuospatial impairments) |
|
|
Dx
Nephrotic syndrome in children with Hep B |
Membranous glomerulonephritis
|
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Electrolyte impairments in alcoholism
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Hypokalemia with exacerbating hypomagnesemia
also hyphophosphatemia |
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Dx
Pain and stiffness in the neck, shoulders, and pelvic girdle with morning stiffness and elevated ESR |
Polymyalgia rheumatica
|
|
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Tx for
Polymyaglia rheumatica without giant cell arteritis |
Low dose prednisone
|
|
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What drug to avoid in preexisting lung disease
|
Amiodarone (causes lung toxicity)
|
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Dx study for
Suspected vasovagal syncope |
Tilt table testing
|
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Dx
Thin walled cavities on CXR in pneumonia |
Staph aureus
|
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Dx study for
Aortic dissection |
Trans Esophageal echo (Not TTE)
or CT with contrast |
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If anemia despite EPO tx in CKD what's the Tx?
|
Iron supplements
|
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Tx for
Hepatic fulminant failure (defined as hepatic encephalopathy within 8 weeks of onset of acute liver failure) |
Liver transplant
|
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Tx for
Hep C with detectable viral load and evidence of damage (LFTs) |
Combined interferon and Ribvarin
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Dx
Vague, headache, n/v and closed air space |
Carbon monoxide poisoning
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Dx
High bp, hypokalemia, metabolic alkalosis, mild hypernatremia, and very low plasma renin activity |
Primary Hyperaldosteronism
|
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Indications for Aortic valve replacement
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1) Symptomatic AS
2) Pts with AS that need CABG 3) AS patients with LV systolic function or valve area less than 0.6 |
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Dx
Large amount of blood in urine on dipstick by few RBCs on microscopy |
Rhabdomyloysis
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Dx
Chronic hepatitis, grey green rings in eyes |
Wilson's disease aka
Hepatolenticular disease |
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Dx
Pain radiating to back, Leukocytosis, markedly elevated serum amylase and lipase |
Acute pancreatitis
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Tx for
Acute pancreatitis |
Conservative tx of analgesics, fluids, and NPO
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Mgmt
Aseptic meningitis of suspected HSV |
Start acyclovir and get cultures later
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Mgmt
Acute GI bleed with ABC jeopardy |
1) Fluids
2) Protect airway with intubation 3) Upper GI endoscopy to find/stop bleeding |
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Dx
Fever, lethargy in settin of chirrhosis and ascites |
Spontaneous bacterial peritonitis
(usually superimposed on liver failure from cirrhosis) |
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Mgmt
Fever, lethargy in settin of chirrhosis and ascites |
Paracentesis
(positive fluid culture and PMNs more than 250 = Spontaneous bacterial peritonitis) |
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Dx
Arteriosclerotic lesions of afferent and efferent renal arterioles |
HTN
|
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Dx
Increased intracellular matrix, basement membrane thickening, and fibrosis |
Diabetic microangiopathy (nephropathy)
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Dx
Leukemia with nonspecific esterase positive |
Acute monocytic leukemia
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Dx
Hypercalcemia in a patient bedridden with truama Tx? |
Immobilization and high bone turnover in healing lead to osteoclast activity
Tx - bisphosphonates |
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|
Dx
Curtain fall vision loss, flashes of light, and floaters |
Retinal detachment
|
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Dx
Shin rash with bilateral lympadenopathy of lungs |
Inflammatory granulomas (sarcoid)
|
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Tx for
Strep viridans bacterial endocarditis |
Ceftriaxone or IV penicillin
|
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Side effect of Herceptin (trastuzumab)
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Cardiotoxicity
|
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Dx
Renal disease in diabetes |
Microangiopathy
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Dx
Blood and thunder fundoscopic exam: optic disc swelling, retinal hemorrhage, dilated veins, cotton wool spots |
Retinal vein occlusion
|
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Dx
Curtain fall vision loss, pallor of optic disc, cherry red fovea, boxcar segmentation of retinal veins |
Central artery occlusion (amareurosis fugax)
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Dx
Small cell lung cancer, with muscle weakness |
Eaton lambert syndrome (autoantibodies to voltage gated Ca channels)
|
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Dx
IV drug user with mutliple nodules in lungs |
Staph aureus vegetation embolizations
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Mgmt
Bleeding in liver failure |
Fresh frozen plasma
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Mgmt
Suspected melanoma |
Excisonal biopsy
(if deeper than 1 mm on biopsy need sentinel lymph node study) |
|
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Dx
Painless hematuria in young black male |
Sicke cell trait
|
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Microcytic anemia with low ferritin
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Iron deficiency anemia
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Most common cause of low iron deficiency
|
GI Bleed
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Low TIBC in the setting of normal ferritin
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Anemia of chronic disease
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Tx Iron deficiency anemia
|
Ferrous sulfate
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Acute tenosynovitis
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Gonorrhea (gonnococcal arthritis)
|
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Poly joint swelling with flexio
|
Tenosynovitis
|
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Sheeps, dogs Infection
|
Echinococcosis
|
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Biliary obstruction (infection)
|
Ascariasis
|
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Severe granulomatous rxn, hepatosplenomegaly, portal htn
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Schistosomiasis
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Popcorn calcifications in round solitary nodule
|
Hamartoma
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Temporal headache, scalp tenderness, sisx of giant cel arteritis
|
Temporal arteritis
|
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Hives with jaundice
|
Hep B
|
|
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Asymptomatic low grade hi PTH and hi Ca
|
No Tx
|
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Iatrogenic Hemolysis in G6PD deficiency
|
Sulfa drugs (e.g. trimethoprim sulfa)
|
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Most common cause of UTI
|
E. coli
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|
|
Dermatitis, dementia, diarrhea (vitamin deficiency)
|
Pellagra aka niacin deficiency
|
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CV dz (high output failure), neurologic (wernicke-korsakoff sx) Vitamin deficiency
|
Beriberi aka Thiamine (B1) deficiency
|
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Macrocytic anemia. Vitamin deficiency
|
B12 deficiency. Etio pernicious anemia, gastrectomy, ileal abnormalities
|
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Osteomalacia in adults, rickets in children. Vitamin Deficiency
|
Vitamin D deficiency
|
|
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Ecchymotic rashes around hair follicles, bledding gums
|
Vitamin C deficiency
|
|
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Microcytic anemia with low ferritin
|
Iron deficiency anemia
|
|
|
Most common cause of low iron deficiency
|
GI Bleed
|
|
|
Low TIBC in the setting of normal ferritin
|
Anemia of chronic disease
|
|
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Tx Iron deficiency anemia
|
Ferrous sulfate
|
|
|
Acute tenosynovitis
|
Gonorrhea (gonnococcal arthritis)
|
|
|
Poly joint swelling with flexio
|
Tenosynovitis
|
|
|
Sheeps, dogs Infection
|
Echinococcosis
|
|
|
Biliary obstruction (infection)
|
Ascariasis
|
|
|
Severe granulomatous rxn, hepatosplenomegaly, portal htn
|
Schistosomiasis
|
|
|
Popcorn calcifications in round solitary nodule
|
Hamartoma
|
|
|
Temporal headache, scalp tenderness, sisx of giant cel arteritis
|
Temporal arteritis
|
|
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Hives with jaundice
|
Hep B
|
|
|
Asymptomatic low grade hi PTH and hi Ca
|
No Tx
|
|
|
Iatrogenic Hemolysis in G6PD deficiency
|
Sulfa drugs (e.g. trimethoprim sulfa)
|
|
|
Most common cause of UTI
|
E. coli
|
|
|
Dermatitis, dementia, diarrhea (vitamin deficiency)
|
Pellagra aka niacin deficiency
|
|
|
CV dz (high output failure), neurologic (wernicke-korsakoff sx) Vitamin deficiency
|
Beriberi aka Thiamine (B1) deficiency
|
|
|
Macrocytic anemia. Vitamin deficiency
|
B12 deficiency. Etio pernicious anemia, gastrectomy, ileal abnormalities
|
|
|
Osteomalacia in adults, rickets in children. Vitamin Deficiency
|
Vitamin D deficiency
|
|
|
Ecchymotic rashes around hair follicles, bledding gums
|
Vitamin C deficiency
|
|
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Drinking vitamin deficiencies
|
Vit C and B1 (thiamine)
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Elevated amylase, elevated lipase, pain radiating to back, “sentinel loo” (air in small bowel LUQ)
|
Acute Pancreatitis
|
|
|
Fever, tonsilar exudate, cervical LAD, no cough
|
Strep Infection (usually pyogenes)
|
|
|
Most common causes of exudative (bacterial) URI
|
Strep pyogenes
|
|
|
50% of AIDS patients have this electolyte abnormality
|
Hyponatremia
|
|
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Acute Tx of hemorrhage
|
1st Saline, 2nd place large bore catheters while blood matching
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Diarrhea in AIDs, Eti and Dx
|
Cryptosporidium or Isospora, AFB stain of stool
|
|
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Gram positive diplococci in PNA
|
Strep Pneumo (pnemococcus)
|
|
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Reduced breath sounds, decreased tactile fremitus
|
Effusion
|
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Reduced breath sounds, increased tactile fremitus
|
Consolidation
|
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Tx for migraine
|
Ergotamine or -Triptans
|
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Prophlaxis for migraines
|
CCBs
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Tx Tension headache (normal headache)
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NSAIDs
|
|
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Cause of kidney stone with pyloneprhritis
|
Proteus mirabilis (makes urine basic leading to stone), Tx is acidic diet, urease inhibitor, and abx
|
|
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Most common GI sx of Scleroderma
|
Esophageal dysfunction (densely fibrotic esphagus)
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Lung kidney things
|
Goodpastures, Wegners, or Churg-strauss
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Lung-kidney dz, with C-ANCA or P-ANCA
|
Wegners C-ANCA, and Churg-Struass = P-ANCA
|
|
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Lung-kidney dz, with hemoptysis, and linear desposition of IgG in glomerulus
|
Good pastures
|
|
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Most common precipitating factor in status epilepticus
|
Drug Non-compliance
|
|
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Hypoxemia, hypoglycemia hypotenstion, hyperthermia
|
Status epilepticus
|
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Sleep apnea with CO2 retention
|
Pickwickian (obesity hypoventilation syndrome)
|
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Morbid obesity, HIV infection, or heroin abuse with nephrotic syndrome
|
Focal segmental glomerulosclerosis
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Diabetic nephropathy
|
Kimmelstiel wilson disease
|
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Childhood nephrotic sx
|
Minimal change diease
|
|
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Crescent shaped cells accumulate in bowman’s capsule
|
Crescentic glomerulonephritis
|
|
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Frank proteinuria
|
Nephrotic Syndrome
|
|
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RBCs and protein in urine
|
Nephritic Syndrome
|
|
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When to use cryoprecipitate
|
DIC, von Willebrand,"", and Hemophilia A
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|
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Most common cause of pericarditis
|
Renal failure (when BUN over 100), treat with HD
|
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Hep A IgM and IgG tells you what
|
IgM acute infection, IgG chronic infxn
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Mitral obstruction by mass in atria
|
Myxoma
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Oral ulcers, genital ulcers, arthritis
|
Bechet’s Sx
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Medullary carcinoma thryoid RF
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MEN
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Papillary carcinoma thryoid RF
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Radiation
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Prolonged QT Tx
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Alkalemic process (like hyperventilation) or bicarb
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|
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Cheesy white exudate on oropharynx in AIDS
|
Thrush from Candida albicans
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Most common cause of HIV retinitis
|
CMV
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Human bite infection
|
Mixed aerobic and anaerobic bacteria
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|
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Dog bite infection
|
Pasteurella multocida (penicilin sensitive)
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Most associated with polymyalgia rheumatica
|
Temporal arteritis
|
|
|
Giving nitroprussides causes hypoxia why?
|
V/Q mismatch from non-specific pulm vasculature dilation, preventing vasoconstriction of poorly perfused areas
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Rapidly progressive respiratory distress
|
ARDS
|
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Neurologic findings separated by time and location.
|
Multiple Sclerosis
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Sensory hearing loss, facial nerve palsy, cerebellar dysfunction, headache
|
Acoustic neuroma
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Initial Tx for Endocarditis
|
Get BCx first, then broad spectrum Abx (to not screw up BCx)
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Tx severe aplastic anemia
|
Bone marrow transplant
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Hives with pigmented spots, that wheal with blunt object stroking.
|
Systemic mastocytosis (too many mast cells)
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Tx for Supraventricular arrhythmia
|
Verapamil (or Class III)
|
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Most common cause of ring enhancing lesions in AIDS in brain
|
Toxoplamosis and Lymphoma (if abx resistant)
|
|
|
Acute angled, branching septated fungus
|
Aspergillus
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|
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Pseudohyphal mycelia with budding yeast cells
|
Candida
|
|
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Owl Eyes
|
Hodgkins lymphoma
|
|
|
Owl eyes + intranuclear and cytoplasmic inclusion bodies
|
CMV
|
|
|
Fever, headache, anemia, elevated ESR
|
Temporal Arteritis
|
|
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Tx Arterial Temporitis
|
Prednisone
|
|
|
Most common cause of chronic pancreatitis
|
Alcoholism
|
|
|
Anti mitochondrial Antibodies
|
.
|
|
|
If no EKG changes with angina, do it with exercisez
|
.
|
|
|
Every diabetic should be on what besides insulin
|
ACE-i
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|
|
Ectopic production ACTH causing cushing
|
Small cell carcinoma of lung
|
|
|
Side effects of amiodarone
|
Pulmonary fibrosis (10%), Prolonged QT (1%), skin discoloration common
|
|
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MS CSF findings
|
Oligoclonal IgG bands, mildly increased protein
|
|
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Tx for cerebral edema following stroke
|
Prednisone
|
|
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Tx to increase penumbra salvage after stroke
|
CCBs, Barbiturates, and NMDA antagonists
|
|
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Cause of abx associated pseudomembranous colitis
|
C Diff
|
|
|
Complication of C Diff pseudomembranous colitis
|
Colonic perforation
|
|
|
Linear burrow holes
|
Scabies, mineral oil Tx
|
|
|
Phenytoin
|
Folate deficiency
|
|
|
Vanillymandeic acid
|
Pheochromocytoma
|
|
|
Rapid shift of Na with fluids causing neurologic damage
|
Central pontine myelinolysis
|
|
|
Stress (hospitilzation) gastritis
|
Acute erosive gastritis with ulcers
|
|
|
Acute htn crisis Tx
|
Nitroprusside
|
|
|
Main complication of hepatic adenoma
|
Rupture into peritoneal cavity
|
|
|
Initial Tx for acute Gout
|
Indomethacin (NSAID) or colchicine (2ndary), prednisone if refractory, and allopurinol long term
|
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Sinus, lung, skin, and kidney dz
|
Wegners
|
|
|
Days of rest for musculoskeletal injury
|
3 days at most
|
|
|
Which Abx cause ATN/AIN
|
Aminoglycosides (e.g. gentamycin) cause ATN, Penicillins cause AIN
|
|
|
RNP
|
Mixed connective tissue dz
|
|
|
c-ANCA
|
Wegner’s
|
|
|
dsDNA
|
Lupus
|
|
|
p-ANCA
|
microscopic polyarteritis
|
|
|
Scl-70
|
Systemic sclerosis
|
|
|
Traumatic brain bleed, lucid interval
|
Epidural bleed
|
|
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LOC, worst headache of life, vomiting
|
Subarachnoid
|
|
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Putamenal or caudate lobe, basal ganglia, LOC, vomiting
|
Hypertensive bleed
|
|
|
Flat emotional affect, language disturbances with dementia
|
Pick dementia
|
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44. Pseudogout= positive bifrengint rhomboids whereas negative befringent needle is gout
|
.
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45. lepromatous leprosy (aggresive) is diff from tb leprosy (milder form, treated w depsone)
|
.
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46. severe sharp chest pain radiating to back and shoulder is classic symptom for aortic dissection
|
.
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47. homeless, alcoholic (aspiration pneumonia) is classically anaerobic (TB is classically in upper lung lobes)
|
.
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48. MRI of brain for not typical cerebral problem s
|
.
|
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49. pneumonia: decreased tactile fremitus over the right hemithorax
|
.
|
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50. sarcoid
|
.
|
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Mononucleosis
|
Splenomegaly + LAD, Heterophil is another name for monospot test, which is positive. Atypical lymphocytes on on blood smears
|
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CLL
|
B lymphocytosis, lymphadenopathy, if only those two, no treatment. First line treatment is chlorambucil. If that fails use fludarabine. Bone marro transplant is reserved for very young patient.
|
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|
DM I
|
Associated w HLA DR3 and DR4
|
|
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Alcoholic Hepatitis
|
AST/ALT is greater than 2
|
|
|
Huntington
|
Familial, irritiablity, restessness, diff. concentration, and onset between 30-50. Autosomal Dominant
|
|
|
Hypervolemia
|
Can cause hyponatremia
|
|
|
Narrow Angle Glaucoma
|
Red Eye, extreme pain, blurred vision with halos most frequent in Asians. Test this with tonometry to test pressure.
|
|
|
Pneumonia in AIDS patients
|
Bacterial pneumonia is the most common form if AIDS patients. MAI causes a wasting systemic disease not like pneumonia. TB has crhonic or subactue, with cough fever and drenching night sweats. PCP only in severe CD4 count depression.
|
|
|
Membranous Glomerulopathy
|
Hep B is the most common infection cause, with syphyillis a second. Most common renal complication in AIDS is focal segmental. C3 refers to IgG which is found in membranoproliferative. IgA is in Berger disease, with flu like symptoms.
|
|
|
Acromegaly
|
Tested after a glucose supression test. People have fluctuating baselines, so you want to try and balance that out by supressing glucose. THEN you do MRI and or CT.
|
|
|
Secondary amenohrea
|
Most Common Pregnancy. Once rule out pregnancy, then CT.
|
|
|
Renal Cell Carcinoma
|
Flank Pain, Hemature, and Abdomina mass. Can cause hematurea, weigh loss. and history cigarette smoking.
|
|
|
Charcot Triad
|
Jaundice, fever, RUQ: cholangitis, Cholecystitis rarely give you fever.
|
|
|
Indirect Billirubinemia
|
Hemolysis (, spherocytosis etc). Cihhrosis only causes diret.
|
|
|
Diabetes and Hypertension
|
Give them an ACE is first line
|
|
|
Hypercholesterolemia
|
most common cause ia defect in the LDL receptor (look up class scheme for memorizing the rest).
|
|
|
Trichinosis
|
Is the nematode, common from boar, bear, pork, or horse. You get muscle invasion, intestinal stage with diarrhea, and blood eosinophilia, elevated creatine kinase. Chagas is caused by trypanosomiasis.
|
|
|
Metabolic Acidosis
|
Need to have Ph standards and also responding appropriately with a respiratory alkalosis.
|
|
|
Aluminum hydroxidde
|
Caused by aluminium containing antacids. Calcium carbonate can cause a hyperphosphatemia.
|
|
|
Alcoholism
|
Associated with carbohydrate deficient transferrin levels.
|
|
|
NSAID use
|
misoprostal supposedly helps, questionable
|
|
|
Mycoplama Pneumonia
|
Erythematous painful papules on the tympanic membranes, and cold agglutinins which precipitate on colloing is pathognomonic for Mycoplasma. Treatment is erytromycin.
|
|
|
Meniere’s Disease
|
Vertigo, Tinnitus, and feeling of swelling.
|
|
|
CREST syndrome
|
only have thicknede skin on theri hadn and face, as opposed to more diffuse.
|
|
|
Reflex Esophagitis
|
Squamous to Columnar metaplasis and goblet cells, is a garrets esophagus. Long fingers is also Barrets.
|
|
|
HOCM
|
Initial therapy is beta blockers, or CCBs.
|
|
|
Central Pontine Myelonlysis
|
demylenination from volume shifts
|
|
|
Hypeparathyroidism
|
Most common casue of hypercalcemia in patients.
|
|
|
Erythema Multiforme
|
Variety of morphologies, sudden onset, also target lesion.
|
|
|
Erythema Migrans
|
Lyme
|
|
|
Suspected Biliary obtruction
|
Start with ultrasound
|
|
|
Ankylosing Spondylitis
|
Early onset, before 40, and involvemtn of sacroilliac joints.
|
|
|
Why would Bacterial endocarditis blood screen be negative
|
BC they got antibiotics before doing teh culture
|
|
|
Steatosis
|
Most common causes are alcohol use, obesity, or DM.
|
|
|
Radial Palsy
|
Triceps, brachioradialsi, wrists, and finger and thumb extensors
|
|
|
PBC
|
Assocaited with antimicrobial autoantibodies
|
|
|
PSC
|
Most associated with Ulcerative Cholitis.
|
|
|
Anti Smooth Muscle
|
Autoimmune chronic hepatitis
|
|
|
Clinically Following Ascites
|
Follow their PT, which is a proxy for synthetic capability. Bleeding time is a marker of platelet function.
|
|
|
Hypothermia
|
helps chances for better outcomes. Sedation is also useful, but only if hypothermia doesnt work. Hyperventilation is only indicated by if there is ICP.
|
|
|
Malignant Hyperthermia
|
Patient was given succinylcholine, which can cause muscular contracture.
|
|
|
Takayasu Arteritis
|
Inflammation of aortic arch or branches, frequently pulseless, can cause ischemia to brain
|
|
|
Wegeners
|
C-Anca
|
|
|
Atopic Dermatitis
|
Is Eczema
|
|
|
Nummular Eczema
|
Coin Shaped Lesions, scaly crust
|
|
|
Seborrheic Dermatitis
|
Scaly oily dandruss rash on the scalp and eyebrows.
|
|
|
Paget Disease
|
Mostly older, Heavy osteoclastic and osteopblastic, coarsely woven, thrick, heavily cacifed but weak. Frontal bossing, bow legs
|
|
|
Schistosomiasis
|
Infective larvae are excreted by snails and penetrate through skin or mucous membrane. Recurrent hematuria and predisposes to squamous cell carcionma. Search for OVA.
|
|
|
Pyelonephritis
|
Start IV ampicillin and gentamycin
|
|
|
Von Willebrand disease
|
Factor VIII deficiency, will extend PTT. Factor VII extend PT. Factor IX will extend PTT, is hemophila B. Hemophilia A is also a IIX deficiency, prolongs PTT< and is x linked.
|
|
|
Fat Emobolism
|
Dyspnea, tachypnea, tachycardia, with diffuse bilateral inflitrates consistent with ARDS and a self limiting petechial rash.
|
|
|
DKA
|
Osmolar diueres: leads to volume depletion, need volume, need insulin, and D5W.
|
|
|
AtlantoAxial joint
|
Upper motor neuron symptoms, so it must be above the heart.
|
|
|
Digoxin Toxicity
|
DIG is renally excreted
|
|
|
Scurvy
|
Vit C deficiency: bleeding from teh gums, capillary fragility, petehia, eccymoses, poor wound healing,
|
|
|
External Otitis- necrotizing/malignant
|
Most Commonly caused by pseudomonal aeruginosa. Cipro is the treatment of choice.
|
|
|
Anti-centromere antibodies
|
Specficially to the CREST variant of systemic sclerosis. Calcinosis, Reynauds, Esophageal dysmotility, Sclerdacyly, telangectasia
|
|
|
Rebound Tendernes and rigid abdomen
|
Describing perforation or its in the peritoneal space.
|
|
|
Pseudogout
|
rhomboidal positive birefringent crystals , Gout is negative needles
|
|
|
Burkitts Scan
|
Starry SKy, Africa
|
|
|
Follicular Small Cleaved Cell lymphoma
|
Waxing and Waning lymphadenopathy,
|
|
|
Ankylosing Spondylitis
|
Seronegative spondyloarthropathy, make sex, young, sacroillitis, large joing arthritis, aortic regurgitattion, low back pain
|
|
|
Menetrier Disease
|
Thickened Gastric folds, low acid secretion, protein loss and edema, weight loss
|
|
|
Scrufulla
|
TB infection in the neck
|
|
|
Positive TB
|
On isoniazid if seropositive for 6 months and have contacts with people with TB
|
|
|
Acute Gout Therapy
|
NSAIDS, then colchicine, then steroids
|
|
|
Caroli Disease
|
Associated wtih biliary cirrhosis, adn can develop hepatic fibrosis. Dilation of intrahepatic bile ducts
|
|
|
Crigler Najjar
|
Inherited enzymatic abnormality of the liver that causes hyperbilirubinemia
|
|
|
Dubin Johnson
|
Enzymatic disorder that causes dark grey liver and hyperbilirubinemia
|
|
|
Gilbert Syndrome
|
Asymptomic hyperbilirubinemia
|
|
|
Rotor Syndrome
|
hyperbilirubinemia without liver discoloration
|
|
|
Malaria
|
Should be looked for in blood smears. They have waxing and waning fevers (three day disease), blood smears should be examined every 8 hours during and between febrile attacks Treatment for malaria is chloroquine.
|
|
|
Myelophthisic Anemia
|
Small schistocytes, fragment, red cells. Happens when your bone marrow cavity is taken over by tumor, fibrosis, or other things.
|
|
|
Hypochromic Macrocytes
|
Folate defiency, vitamin B12, and thalassemia
|
|
|
Ringed Sideroblasts
|
Sideroblastic anemia, problem with erythrocyt maturation adn utilization iron
|
|
|
Cholecystitis
|
Symptomatic, treat with lap coli
|
|
|
Anal Cancer
|
HPV
|
|
|
Neutrophilic predominant
|
Baterial, Lymphocytic (less bacterial)
|
|
|
CEA
|
Colon Cancer. AFP liver, ovary, and testicular Cancer.
|
|
|
Atypical Pneumonia
|
Mycoplasma pneumoniae, chlamydia, coxiella burnetti. THe interstial patter is what characteristics.
|
|
|
Magnesium Deficiency
|
Malabsorption, or kwashiorker, . CHronic alcoholism is another cause of magnesium deficiency.
|
|
|
Hemochromatosis
|
hepatomegaly, arthlargias, skin hyperpigmentation. HFE protein mutation.
|
|
|
Treatment of Prolactinoma
|
is bromocriptine
|
|
|
Hypertensive Hemorrhage
|
MOst common in putamen, but if the symptoms are cerebellar, then its cerebellum. Putamenal hemorrhage usually leads to contralaeral hemiparesis, hemianesthesia, and hemianopia
|
|
|
Basal Cell Carcinoma
|
Most common cause, pearly, rolled edges. Melanoma pigmentation. For squamous stuck on appearance, not ulcerated.
|
|
|
OSA
|
Poor nightitme sleeping, day time sleepiness
|
|
|
Prostatic Hyperplasia
|
If IV contrast posioning, its going to be within 24 hours, not a week.
|
|
|
Alcoholic aspiration pneumonia
|
Klebsiella
|
|
|
Inferior MI
|
RCA occlusion
|
|
|
Coffee ground emesis, pain killers
|
gastric ulcers
|
|
|
quick onset food poisoning
|
Staph aureus, B cereus
|
|
|
most common cause of hemoptysis in adults
|
chronic bronchitis
|
|
|
Vit K def.
|
Abx can cause Vit K def, but also TPN
|
|
|
Hyperpigmentation and hypocortisol
|
Addisons
|
|
|
Constrictive Pericarditis
|
Increased venous distension on inspiration (kussmaul’s sign)
|
|
|
Radioactive Iodine Scan
|
only needed if there are symptoms of thyrotoxicosis. If there are no symptoms and there is a nodule for FNA to make sure its benign.
|
|
|
Brain Abscess
|
Afebrile, and can exhibit progressive neurologic symptoms
|
|
|
Psyllium
|
A bulking agent that you use before laxatives.
|
|
|
Aplastic Anemia
|
Fat in bone marrow.
|
|
|
Ramsay Hunt
|
Cranial Nerve 8 with shingles. Vesicles in the ear. Facial Palsay
|
|
|
Menieres Disease
|
One sided Tinnitus, Deaffness, and vertigo. Fullness
|
|
|
Pityriasis Rosea
|
Scaly lesion that involves the trunk, sometimes a christmas tree appearance
|
|
|
Pityrisasis Rubra pilaria
|
involves the hands and soles and does not produce a herald patch
|
|
|
Scabies
|
Small skin burrows in addition to papules, itching is prominent
|
|
|
Rovsing Sign
|
Acute pendicitis
|
|
|
Htn
|
Confirm within two months
|
|
|
Hypoparathyroidism
|
Feedback inhibition
|
|
|
Hungry Bone syndrom
|
Will happen days or weeks, with patients with hyperparathyroidism
|
|
|
Syphillis
|
Use penicillin, if theyre allergic use doxycycline.
|
|
|
alcohol cardiomyopathy
|
Leads to dilated. S3 is also indicative of dilated.
|
|
|
Antiphospholipid Antibody
|
Hypercoagulable (or anticardiolipin), can lead to thrombosis
|
|
|
Acute adrenal insufficiancy
|
It happens when you remove steroids, treate w IV hydrocortisone, adn then confirm diagnosis by measuring. confirm by measuring cortisol levels
|
|
|
Mesothelioma
|
Smoking is not a risk factor, Asbestos.
|
|
|
Tear Drop
|
Idiopathic myelofibrosis. The bone marrow is crying, also wil have bone marrow fibrosis `
|
|
|
Increased RBC mass
|
PVERA
|
|
|
Acetaminophen Entoxication
|
7 grams is necessary, unless you already have liver dysfunction
|
|
|
Medullary Carcinoma
|
Men 2a associated with medullary cancer, treat!
|
|
|
paracetomol
|
aspirin.
|
|
|
Antirheumatics
|
For disease progression, use Nsaids and steroids for symptom control
|
|
|
Neomycin
|
Lactulose is given classically to wash out the bateria, and neomycin, a poorly absorbed aminoglycoside, that allows it to destory the ammonia producing bacteria
|
|
|
Dig Toxicity
|
yellow green cast to the vision, also known as xanthopsia/verdopsia, bradycardia
|
|
|
Conn Disease
|
Primary hyperaldosteronism
|
|
|
Hashimoto thyroiditis
|
Goiter, antibodies against thyroglobulin, and with lymphocytes.
|
|
|
B thall
|
Do electrophoresis. RDW is less than 15%. In iron def. there is more deficiency, and RDW is greater than 15%
|
|
|
Kidneys plus HTN
|
ace inhibitor
|
|
|
Sickle Cell
|
Hydration and Narcotics
|
|
|
Howell Jolly Body
|
rbcs with their nucleus
|
|
|
Nephrotic syndrome
|
you lose anticoagulant proteins
|
|
|
Hodkins (stage IV)
|
Treat with chemo
|
|
|
G6PD
|
fava bean, done, heinz bodies, makes cells vuln. to cell damage
|
|
|
Pancreatic CAncer
|
Look at amylase, lipase
|
|
|
EPO in the setting of CKD, dialysis
|
can cause hypertension in 20% of cases
|
|
|
Effect on dexamethasone test and what it tells you.
|
Decrease ACTH secretion by pituitary only, so if ACTH or cortisol remains high, non pituitary source.
|
|
|
Startle myoclonus (jerks causes by loud noises)
|
Creutzfeld Jakob
|
|
|
Why is lung cancer screening not effective?
|
Even when primary tumors are detected, bc high rates of metastasis are usually already present
|
|
|
First treatment in hypercalemia
|
Restore volume. Hypercalemic pts are dehydrated, restoring improves GFR and Ca clearance.
|
|
|
Cough, fever, and yellow sputum in healthy person. Dx?
|
Acute bronchitis
|
|
|
First imaging in Diverticular Disease?
|
You want to do a barium enema, but you need an x-ray first to make sure there are no perforations first.
|
|
|
Insulin high, C-peptide low, insulin AB
|
Exogenous source of insulin.
|
|
|
Exposure to plants, chain of lesions. Dx?
|
Sporotrichosis
|
|
|
Tapping causes facial twitch. Dx?
|
Hypocalcemia (Chvostek sign)
|
|
|
Hyperpigmented, sharply marginates lesions on healthy person. Dx?
|
Melasma
|
|
|
Signs of cholestasis + antimitochondrial Ab. Dx?
|
Primary biliary cirrhosis
|
|
|
% HCV infection that becomes chronic
|
75% (HBV, 5-10%)
|
|
|
Patchy hypopigmentation of skin. Dx?
|
Vitiligo
|
|
|
Antihypertensive med that causes hyperkalemia
|
ACE inhibitors
|
|
|
Painful thyroid gland. DDx?
|
Subacute thyroiditis
|
|
|
Delayed carotid upstroke
|
Aortic stenosis
|
|
|
Hyperbilirubinemia with otherwise normal lab values & no other symptoms. Dx?
|
Gilbert’s syndrome
|
|
|
Slowly developing nodular lesion with central ulceration. Dx?
|
Basal cell carcinoma
|
|
|
Most important factor affecting long-term success of TIPS or liver transplant
|
Abstinence from alcohol
|
|
|
Diagnostic test for suspected pituitary adenoma
|
Serum prolactin (before head MRI)
|
|
|
Fungus in the Southwest US
|
Coccidioides immitis
|
|
|
Elderly patient with subacute onset of dementia, urinary incontinence, gait disturbance
|
Normal pressure hydrocephalus
|
|
|
Procollagen I deficiency
|
Osteogenesis imperfecta
|
|
|
Cryptococcal meningitis tx
|
Amphotericin B (the oral fluconazole)
|
|
|
Proximal weakness & elevated CPK
|
Polymyositis
|
|
|
Polymyositis tx
|
Corticosteroids
|
|
|
Cause of black pigment gallbladder stones
|
Hemolysis
|
|
|
Cause of brown pigment gallbladder stones
|
Infected bile
|
|
|
Elevated urinary 5-hydroxyindoleacetic acid (5-HIAA)
|
Carcinoid syndrome (5-HIAA = serotonin metabolite)
|
|
|
Elevated urinary vanillylmandelic acid (VMA)
|
Pheo (VMA = catecholamine metabolite)
|
|
|
MALT lymphoma tx
|
Antibiotics (to eradicate H pylori)
|
|
|
Positive direct Coombs test
|
Autoimmune hemolytic anemia (detects C’ or Ab on RBC)
|
|
|
Cold agglutinins
|
#ERROR!
|
|
|
Loss of speech discrimination + tinnitus
|
Schwannoma of CN VIII (aka acoustic neurinoma)
|
|
|
Ascending paralysis
|
Guillain-Barre
|
|
|
2,5, and 10 LRs correlate to what additional post test probabilities
|
15%, 30% and 45%
|
|
|
Triple AAA screening
|
Male between 65 and 75 and ever smoked.
|
|
|
When to get pneumovax?
|
Everyone over 65. If active smoker, COPD, or asthma they should get it earlier.
|
|
|
Who can get live attenuated flu vaccine intranasally?
|
Less than 50, immuncompetent with no immunosuppressed contacts.
|
|
|
Who definitely needs Flu vaccine?
|
Everyone. And can be dead or attenuated unless immunosuprressed.
|
|
|
Who should get zoster vaccine?
|
All immunocompetent 60 and older regardless of prior hx.
|
|
|
Who gets Tdap?
|
All between 19-64 who haven’t gotten booster.
|
|
|
When to give Tdap immunoglobulin.
|
Patients with wound who do not have reliable Tdap hx.
|
|
|
Who doesn’t need Tdap?
|
If they had Tdap within 5 years, or have a clear wound and a Tdap within 10 years.
|
|
|
Who should get HVP vaccine?
|
All girls 9-26
|
|
|
Acceptable Colorectal screening options (4)
|
1. Colonoscopy every 10 years starting at 50
|
|
|
Syncope in heart failure with ischemia. Dx?
|
Vtach
|
|
|
Common cause of syncope, must check this test especialy in diabetics.
|
Orthostatics
|
|
|
Syncope with prodrome of nausea, light-headedness, and diaphoresis. Dx?
|
Vasovagal (situational/neurocardiogenic) syncope
|
|
|
Syncope with lack of prodrome. Dx?
|
Arrhythmia
|
|
|
Best diagnostic study for infrequent but recurrent syncope.
|
Loop recorder
|
|
|
Tx if first anti-depressant fails.
|
Another antidepressant.
|
|
|
Tx for suicidal ideation
|
Urgent inpatient admission
|
|
|
When bereavement becomes inappropriate and should be considered for SSRI
|
At least 2 consecutive weeks of depression 8 weeks after death of loved one
|
|
|
Hx of self harm, dysfuntional relationships, intense anger. Dx?
|
Borderline personality disorder
|
|
|
First line Tx for acute alcohol withdrawal.
|
Lorazepam (ativan)
|
|
|
Tx for acute cocaine intoxication
|
Benzos (lorazepam)
|
|
|
Why can’t you give B blockers to coacine ODs?
|
Selective beta blockers will block the sympathetic effects on heart, while the cocaine alpha vasoconstricts the vasculature. Can give non-selective beta blockers.
|
|
|
When to give haloperidol?
|
When psychosis present
|
|
|
Tx for drug induced seizure
|
Benzo (not anti-epileptic)
|
|
|
Tx to prevent relapse in alcoholism?
|
Naltrexone (also can be used for opioid addiction)
|
|
|
Tx for acute opioid overdose
|
Naloxone (narcan)
|
|
|
Tx for long term opiate addiction
|
Suboxone (buprenorphine)
|
|
|
Screening for alcoholism
|
CAGE
|
|
|
Initial tx for spinal stenosis. Refractory tx especially if neurologic impairment.
|
NSAIDs. Surgery for refractory.
|
|
|
Diagnostic study for back pain, with possible infection.
|
MRI bc can detect acute osteomyelitis changes that CT and x-ray can’t
|
|
|
Tx for acute non-specific low back pain.
|
NSAIDs or acetaminophen
|
|
|
Dx back pain, muscle weakness, bowel or bladder incontinence.
|
Spinal cord compression
|
|
|
Dx study Cancer patients with possible spinal cord compression
|
MRI of spine
|
|
|
Tx for cough variant asthma
|
Albuterol inhaler trial
|
|
|
Tx for chronic cough without CXR findings
|
Anti-histamine and decongestant
|
|
|
Diagnostic study for hemoptysis in healthy and cancer suspicion
|
Healthy - CXR
|
|
|
Tx for acute bronchitis
|
Symptom management (if over 3 weeks, get CXR)
|
|
|
Lung function improvement in COPD following smoking cessation.
|
Improved lung function (2%) and decreased rate of decline by half
|
|
|
Cardiovascular risk relation to smoking status
|
Pack years are irrelevant, but stopping smoking rapidly improves outcome within 5 years of cessation.
|
|
|
Tx for smoking cessation
|
First line - Verenicline
|
|
|
Indications for bariatric surgery
|
BMI over 35 with co-morbidities, or over 40 without comorbidities AND unsuccessful weight loss with diet and drugs.
|
|
|
Tx for pharmacologic treatment of obesity
|
Orlistat
|
|
|
Dx Nausea and vomiting following bariatric surgery
|
Stomal stenosis
|
|
|
Dx study Stomal Stenosis suspicion after bariatric surgery
|
Upper endoscopy
|
|
|
Dx for weight loss, lack of focal sx, lack of f/c/ns, and normal labs and imaging.
|
Re-evaluate in 6 months
|
|
|
Dx systemic weight loss, skeletal muscle dysfunction, osteoporosis, and depression with trouble breathing.
|
COPD
|
|
|
Tx for excessive menstrual bleeding
|
If considerable - medroxyprogesterone
|
|
|
If less - Oral contraceptives
|
.
|
|
|
Dx Oligomenorrhea, hirsutism, acne, alopecia
|
PCOS
|
|
|
Tx for menopausal sx
|
Estrogen replacement therapy
|
|
|
Dx for secondary ammenorrhea
|
Progestin withdrawal study
|
|
|
Initial Dx study for amenorrhea
|
FSH, TSH, and prolactin levels
|
|
|
Dx study for Abnormal uterine bleeding in over 35
|
Endometrial biopsy to diagnose most likely cause (endometriosis) and rule out cancer or hyperplasia
|
|
|
Dx well demarcated, rapidly spreading area of warmth, swelling, tenderness, and erythema.
|
Cellulitis
|
|
|
Dx erythematous, dry or greasy scales and crusts.
|
Seborrheic dermatitis (dandruff)
|
|
|
Dx Pink/red papules and thin plaques with scaling active borders and central clearing.
|
Tinea cruris
|
|
|
Acute, severe, reaction after drug use with erythematous macules and plaques involving mucus membranes but less than 10% of body.
|
Steven Johnson syndrome
|
|
|
Red Man Sx rxn to what?
|
Vancomycin
|
|
|
Dx targetoid lesions, with skin and mucusoal involvement
|
Erythema multiforme
|
|
|
Dx Spreading ring of erythema
|
Erythema migrans (Lyme)
|
|
|
Dx Subtle, fine, pink Blanching macules and papules that spreads centripetally
|
Rocky mountain spotted fever
|
|
|
Tx for shingles
|
Oral valcyclovir or famcyclovir
|
|
|
Dx erythema, telangiectasias, pustules, and sebaceous hyperplasia, that does not spare nasolabial folds.
|
Rosacea
|
|
|
Dx common, benign neoplasms that are black or brown, well demarcated, stuck on with waxy surface.
|
Seborrheic keratosis
|
|
|
Tx for non-inflammatory acne, mild inflammatory, or gross inflammatory
|
1) Benzoyl peroxide, salicylic acid, or retinoids
|
|
|
Dx acute, rapid wheal, superficial, itchy, discrete swelling, lasting less than 24 hours
|
Acute urticaria (chronic if more than 24 hours)
|
|
|
Dx study for isolated axillary lymphadenopathy that is immobile
|
Lymph node biopsy
|
|
|
New onset urinary incontince causes (DIAPERS)
|
Drugs
|
|
|
Dx study for Elderly hearing impairment
|
Whispered voice test
|
|
|
Dx study for Gait and balance problems
|
Get up and Go test
|
|
|
Tx for Urge urinary incontinence
|
Tolterodine or Oxybutynin (anticholinergics)
|
|
|
Dx Slow urinary stream, urinary hesitancy, and nocturia
|
BPH
|
|
|
Chlorthalidone is what class?
|
Hydrochlorothiazide diuretic
|
|
|
Target bp for T2DM?
|
130/80
|
|
|
Dx systemic htn, radial to femoral artery delay, and rib notching.
|
Coarctation of aorta
|
|
|
Stages of HTN and initial Tx
|
Stage 1 - 140/90 (HCTZ)
|
|
|
Lateral epicondylitis (tennis elbow)
|
lateral elbow pain on wrist extension.
|
|
|
Rheumatoid
|
PIP is always rheumatoid. Heberdeens nodes are DIP, bouchards are PIP
|
|
|
Trochanteric Bursitis
|
Localized hip pain, and resisted abduction of the hip worsens the pain
|
|
|
Positive McMurray Test
|
Meniscal Tear
|
|
|
Anserine Bursitis
|
Focal tenderness on the upper, inner tibia, about 5 cm distal to the medial articular line of the knee
|
|
|
Rotator Cuff Tendinitis
|
Think baseball pitcher, subacromial tenderness, pain reaching overhead or lying on shoulder
|
|
|
Adhesive capsulitis
|
decreased ROM, stiffness not pain or weakness
|
|
|
Torn Rotator Cuff
|
positive drop arm test (cant smoothly drop arm)
|
|
|
Polymyalgia Rheumatica
|
15% of people w this have temporal arteritis. 50% of people with temporal arteritis have polymyalgia rheumatica. Pain with neck shoulders and hips. Treat w methotrexate as a steroid sparing agent.
|
|
|
Tx for Community acquired septic arthritis with G+ cocci
|
Vancomycin (cover for possible MRSA)
|
|
|
Tx for Gonoccocal septic arthritis (G- cocci)
|
Ceftriaxone
|
|
|
Acute monoarthritis
|
Is septic until proven otherwise. Need to do arthrocentesis.
|
|
|
Dx Pain in the absence of fever and leukocytes in patient with prosthetic joint
|
Prosthetic joint infection (sic)
|
|
|
Treatment of GOUT
|
Indomethacin (is an NSAID), then colchicine and steroids
|
|
|
Changing Gout therapy
|
Initiating or changing allopurinol levels must be done w prophylactic nsaids, colchicine, or steroids to avoid an acute attack
|
|
|
Pseudogout
|
Positive birefringent rhomboids
|
|
|
OA
|
pain that worsens w activity, relieved by rest, key is that thereis no erythema or warmth. First line therapy is PT
|
|
|
De quervain tenosynovitis
|
pain on palpation of distal aspect of radial styloid. finkelstein test is positive.
|
|
|
Dx Chronic pain at base of thumb with positive grind test
|
OA of thumb
|
|
|
OA
|
First line is acetaminophen + PT, if that fails, then use NSAIDS
|
|
|
Dx joint space narrowing, subchondral sclerosis, osteophyte formation
|
OA
|
|
|
Dx study for suspected RA (best sensitivity)
|
X-ray, look for erosions of cartilage, joint space narrowing
|
|
|
Start TNF alpha, then what?
|
Check tuberculin skin test. Why? Reactive TB
|
|
|
Tx for RA (3)
|
1) Initially NSAIDs and DMARDs (methotrexate) hepatoxicity is possible, use hydroxychloroquine then
|
|
|
HLA-B27
|
Ankylosing Spondylitis
|
|
|
Dx oligoarticular arthritis involving lower extremities in setting of IBD
|
Enteropathic arthritis
|
|
|
When there is an explosive onset of psoriasis
|
Think the Hivvy
|
|
|
Most commonly systemic illness in pts. with anterior uveitis
|
reactive arthritis, ankylosing spondyltitis, and sarcoidosis
|
|
|
Dx of Ankylosing spondylitis
|
MRI of sacroilliac joints
|
|
|
Anti DS DNA
|
SLE
|
|
|
Antiribonucleoprotein antibody
|
Mixed connective tissue diease
|
|
|
AntiSSA SSB (ro-la)
|
sjogrens, (also in subactute cutaneous lupus)
|
|
|
Anti topoisomerase (anti scl 70),
|
scleraderma
|
|
|
Drug Induced lupus treatment
|
Seen with methotrexate use, stop the drug, treat w prednisone to control pleuritis and synovitis associated
|
|
|
Lupus Nephritis
|
Treat with high dose corticosteroids, and ACE inhibitors
|
|
|
Comorbidities of polymyositis and dermatomyositis
|
ILD with progressive fibrosis and secondary PAH.
|
|
|
Dx Diffuse pain on both sides of body, above and below waist, as well as axial skeletal pain.
|
Fibromylagia
|
|
|
Tx of Raynauds
|
CCBs (amlodipine)
|
|
|
Polyarteritis Nodosa
|
Necrotizing inflammation of the medium sized or small arteries. Fever, msk, affects the kidneys, causes htn,
|
|
|
Dx HA, temporal artery tenderness, acute visual loss, dever, milad anemia.
|
Giant cell arteritis
|
|
|
Tx for Giant cell arteritis
|
Immediate corticosteroid Tx even before diagnostic testing
|
|
|
Abdominal Fat pad aspiration
|
AL amyloidosis diagnosis
|
|
|
Dx CP with exertion, Trop negative, EKG negative
|
Stable angina
|
|
|
Dx CP even at rest or unpredictable/increasing, Trop negative, no ST elevation
|
Unstable angina
|
|
|
Dx CP even at rest or unpredictable/increasing, Trop positive, no ST elevation
|
NSTEMI
|
|
|
Dx CP even at rest or unpredictable/increasing, Trop positive, ST elevation
|
STEMI
|
|
|
Need 2 of 3 of these to Dx acute pericarditis
|
1) Pleuritic CP (worst when supine)
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Tx for STEMI
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Percutaneous angioplasty and stent placement (unless PCI more than 3 hrs away, then do thrombolysis within 12 hrs)
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Dx CP with predictable relation to exercise relieved with nitroglycerin
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Stable Angina pectoris
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Dx Acute hypotension, clear lung fields, elevated central venous pressure (Right precordial ST elevations)
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Right ventricular MI
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Tx for Esophageal noncardiac CP
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Empiric proton pump inhibitor
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Most common cause of marked bradycaria and manifests as absence of atrial ventricular association
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3rd degree heart block
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Dx palpitations, sweating, tremulousness, dyspnea, CP, nausea, dizziness, numbnees.
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Panic attack
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Tx for recurrent panic attacks
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SSRI (paroxetine) and CBT
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Dx Severe headache, diaphoresis, palpitations
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Pheochromocytoma
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Dx Progressive prolongation of PR interval
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Mobitz type I (2nd degree AV block)
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Tx for Stable angina (initial medical)
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1) ASA
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Dx CP, dyspnea, leg edema, elevated CVP, tachypnea, and tachycardia
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PE
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Dx study for suspected PE
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CT Pulmonary angiography (PE protocol)
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What does normal wall motion on ECHO during CP allow you to do?
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Exclude coronary ischemia and infarction.
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Dx study for atypical CP with normal resting EKG
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Exercise stress EKG test
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Dx Narrow complex, regular tachycardia, absent p waves, but sawtooth baseline
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Aflutter
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Dx Either symptomatic sinus bradycaria, OR tachy-brady sx
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Sick sinus syndrome
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Dx PR interval greater than 200 ms
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1st Degree AV Block
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1. Tactile fremitus decreased and dullness to percussion over area; rales, crackles or bronchial breath sounds; egophony, bronchophony, and whispered pectoriloquy: Pneumonia PE findings
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2. Fever, productive cough, elevated WBCs, hypoxemia, new lung infiltrate → Pneumonia
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3. Lobar consolidation in pneumonia → Strep pneumo
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4. Interstitial infiltrates in pneumonia → Mycobacterium pneumia or Pneumocystis carinii
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5. Cavitary pneumonia → anaerobes, gram negative, or tuberculous pneumonia
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6. Pleural effusion → Strep pneumo
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Dx
Pruritis after bathing |
Polycythemia vera
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Leukesterase means what?
Nitries mean what? |
Leukesterase = infection of UTI
Nitrites = enterobacter infection |
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Dx
Spasticity, bulbar symptoms, hyperreflexia, fasciculations |
ALS
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Tx for
HA, nausea, eye pain, vision loss, redness in eye |
Dx is acute glacucoma
Tx is Mannitol, acetozolamide, pilocarpine, +/- Timolol |
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Dx
Fever, hypotension, generalized erythema, desquamation |
Toxic shock syndrome
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