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17 Cards in this Set

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What are some of the causes of prerenal azotemia?
hypovovolemia (dehydration, burns, diuretics, vomiting, hemorrhage)
Hypotension (shock, renal artery stenosis)
third spacing fluids (
intravascular volume depletion
decreased CO (CHF,
Low albumin (nephrotic syndrome)
What are the lab values consistent with prerenal azotemia?
Bun:creatinine ratio
urine Na
FeNa
urine osmolality
urine specific gravity
Bun:creatinine ratio: 20:1
urine Na: low
FeNa: < 1%
urine osmolality: high
urine specific gravity: high (> 1.010
What effects does ACE inhibitors have on the renal system.
What pt are prone to having this problem
-can cause a prerenal failure due to dilation of efferent arterioles
-pt at risk: elderly, diabetics, hypertensive
T or F
You cannot get renal failure by the obstruction of only a single kidney if pt has both kidneys in place
TRUE
What are some of the causes of postrenal azotemia?
bladder cancer
prostate hypertrophy (most common)
bilateral renal disease
neurogenic bladder
What are the 2 major causes of ATN
Ischemic
Toxic injury
What are the 3 phases of ATN?
Prodrome: acute injury
Oliguric (<400ml/hr) or Anuric (<100ml/hr)
Postoliguric- diuretic phase
What are values consistent with ATN?
BUN:creatinin ratio
urine Na
urine osmolality
BUN:creatinin ratio: 10:1
urine Na: high
urine osmolality: < 350
How can you tell the difference between prerenal and ATN on lab values?
Urine osmolarity:
Urine Na
FeNa
Urine sediment
Prerenal:
Urine osmolarity: > 500
Urine Na: < 20
FeNa: < 1%
Urine sediment: scant

ATN
Urine osmolarity: < 350
Urine Na: > 40
FeNa: > 1%
Urine sediment: brown pigmented granular cast
What are the symptoms ass. with allergic interstitial nephritis?

What are the drugs?
-fever
-rash
-eosinophile in urine
Drugs: penicillins, NSAIDS, PPI, sulfa drugs, diuretics
What test is important to order when a pt presents with rhabdomyolysis?
EKG or potassium level (peaked T waves)
-Acidosis and hyperkalemia can lead to arrhythmia
What is the tx for hyperkalemia?
calcium chloride
calcium gluconate
What are the metabolic disturbances that can occur in rabdomyolysis?
hyperphosphatemia
hyperkalemia
hypocalcemia
hyperuricemia
What is an important disease that can occur after angioplasty?
What are some of the physical findings?
Atheroembolic disease

-esinophilia
-low complement levels
-bluish discoloration of fingers and toes
-livedo reticularis
Can NSAIDS cause renal failure and if so by what mechanism?
YES
-interstitial nephritis
-direct toxic effect on tubules
-papillary necrosis
-glomerulonephritis

(most pt will have underling renal problems)
A pt presents with very acute flank pain, hematuria, pyuria and fever. Cultures grew no organism
What could be the cause?
Papillary necrosis
-seen in: sickle cell, DM, chronic phyelo, NSAID use

Best test: CT scan
If a pt with underlying renal disease and needs a CT scan what can you do?
Hydration 1-2 liters of normal saline over 12 hrs

Bicarbonate or N acetyl cystine