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12 Cards in this Set
- Front
- Back
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What is Therapeutic Index?
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Estimates the margin of safety of a drug
Measures the Effective Dose (ED) and Lethal Dose (LD) in 50% of people |
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What is the significance of a low therapeutic index?
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Has a narrow margin of safety.
A small safety range between the ED and the LD. The closer the ratio is to one the greater the risk to toxicity |
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High Therapeutic Index
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Wide margin of safety
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What is the normal range for Creatinine Clearance
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85-135 ml/min
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What is the normal Creatinine Clearance for elderly patients?
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60 ml/min
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What size needle would you use for an Intradermal (ID) injection?
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25-27 g, 3/8 - 5/8 inch
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What size needle for a subcutaneous (subQ) injection?
How much solution per site would you inject? |
25-27 g, 1/2 - 5/8 inch
0.5-1 ml per site |
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What site would you use to inject Heparin or Lovenox?
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Abdomen only
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Which has a faster absorbtion rate, subQ or IM?
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IM has faster absorption than subQ
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What size needle would you use for an Intramuscular (IM) injection?
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20-23 g, normally 1.5 inch
Obese may need 3 inch needle Thin may need 1/2-1 inch needle |
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How much solution would you inject into the deltoid muscle (IM)?
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No more than 1 ml
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How much solution would you inject (IM) in other sites?
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Normal well developed adult can get 3ml per site
Elderly/Thin pt 2 ml per site |
