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15 Cards in this Set
- Front
- Back
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thrombolytic problems?
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tamoxifen
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for ER (+) B/C only?
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tamoxifen
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treat chemo-induced neutropenia?
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filgrastim, sargramostim (CSF analogs)
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inhibits DHFR, thymidylate synthetase, transformylase?
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MTX
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non-cancer uses of MTX?
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psoriasis, RA
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how does leucovorin work/
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inhibits MTX pathway in normal cells to prevent damage to them. (mtx not very specific)
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inhibits thymidylate synthase with a ternary complex?
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5-FU
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inhibits DNA poly, fragmentation, apoptosis?
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Ara-C
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2 that inhibit purine synthesis?
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6-thioguanine, 6-mercaptopurine
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which causes hepatotoxicity?
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6-MC
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inhibits adenosine deaminase and ribonucleotide reductase?
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pentostatin
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used for HCL?
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pentostatin
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decrease dose with kidney DX?
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pentostatin
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quinones that intercalate into DNA?
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D/D
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antagonizes testosterone at androgen receptors?
desensitizes pituitary gland to testosterone? |
flutamine
leuoprolide |
