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15 Cards in this Set

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thrombolytic problems?
tamoxifen
for ER (+) B/C only?
tamoxifen
treat chemo-induced neutropenia?
filgrastim, sargramostim (CSF analogs)
inhibits DHFR, thymidylate synthetase, transformylase?
MTX
non-cancer uses of MTX?
psoriasis, RA
how does leucovorin work/
inhibits MTX pathway in normal cells to prevent damage to them. (mtx not very specific)
inhibits thymidylate synthase with a ternary complex?
5-FU
inhibits DNA poly, fragmentation, apoptosis?
Ara-C
2 that inhibit purine synthesis?
6-thioguanine, 6-mercaptopurine
which causes hepatotoxicity?
6-MC
inhibits adenosine deaminase and ribonucleotide reductase?
pentostatin
used for HCL?
pentostatin
decrease dose with kidney DX?
pentostatin
quinones that intercalate into DNA?
D/D
antagonizes testosterone at androgen receptors?

desensitizes pituitary gland to testosterone?
flutamine

leuoprolide