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86 Cards in this Set

  • Front
  • Back

Epidermis

Outer layer of epidermis

Stratum Corneum

Second sublayer of epidermis

Basal layer

3rd sublayer of epidermis

Dermis

Second layer of skin, also called Corium, directly below epidermis, composed of living tissue

Keratin

Basal skin cells form this as they migrate toward the stratum corneum to replace cells a they slough off

Melanocytes

Basal cells that produce melanin

Albino

Unable to produce melanin

Sebaceous gland

Oil gland in dermis.

Sudoriferious gland

Sweat gland in dermis

Subcutaneous layer

Also called hypodermis, binds the dermis to underlying structures, composed of adipose and connective tissue. Stores fat, insulates and cushions body, and regulates temps.

Axillae

Armpits

Sebum

Oily secretion from sebaceous gland

Ductules

Small ducts, when sebaceous ductules are blocked acne can result

Androgens

Sex hormones that regulates secretion of sebum

Androgen

Hormone, testosterone and androsterone that stimulate development of male characteristics

Stratum Germinativum

Another name for Basal layer

Adip/o, Lip/o, Steat/o

Fat

Lipocele

Hernia containing fat

Adiposis

Abnormal accumulation of fat

Cutane/o, Dermat/o, Derm/o

Pertaining to the skin. (Ex. Dermatoplasty, subcutaneous, hypodermic)

Hidr/o, sudur/o

Relating to sweat. (Ex. Hidradenitis - inflammation of sweat gland, sudoresis - profuse sweating)

Icthy/o

Dry, scaly

Kerat/o

Horny tissue, hard, cornea (keratosis- increase - used primarily with blood cells)

Melan/o

Black. Melanoma - black tumor

Myc/o

Fungus, fungi

Onych/o, ungu/o

Nail. (Ex. Onychomalacia - softening of nails; Ungual - pertaining to nails)

Pil/o, Trich/o

Hair. (Ex pilonidal hair in a nest, trichopathy - disease involving hair)

Scler/o

Hardening; sclera (white of eye)

Seb/o

Sebum, sebaceous (ex seborrhea)

Squam/o

Scale. (Ex squamous - scaly)

Xen/o

Foreign; strange (ex. xenograft - Foreign transplantation)

Xer/o

Dry (ex. Xerostomia - dry mouth)

Primary and secondary lesions

Initial reaction to pathology and changes to primary lesions

Macule

Flat pigmented 1cm or less diameter

Papule

Elevated lesion ex wart, nevus, eczema

Vesicle

Elevated, fluid filled lesion less than 0.5 cm (ex. Chicken pox, poison ivy)

Nodule

Solid lesion deeper than papule, extends into dermal area (ex. Tumor)

Pustule

Elevated, fluid filled lesion, less than 1cm diam (ex. Acne, furuncle, scabies)

Tumor

Elevated, solid lesion, larger than 2 cm extending into dermal and subcutaneous layer. (Ex. Lipoma, steatoma)

Wheal

Elevated, solid lesion, with localized skin edema, varies in size shape and color, itchy (ex. Hours, insect bites, urticaria)

Bulla

Elevated, fluid filled lesion, vesicle or blister smaller than 1cm in diameter. (Ex. Second degree burns, poison oak, ivy)

Excoriations

Secondary depressed lesion, scratch marks or traumatized abrasion of epidermis (ex. Scratches, thermal or chemical burns)

Fissure

Depressed secondary lesion, slit or crack, extends into dermal layer caused by continuous inflammation or drying.

Ulcer

Secondary depressed lesion, open sore extending to dermis. (Ex. Pressure sore, basal cell carcinoma)

Alopecia

Hair loss

Anaplasia

Loss cellular differentiator and of function

Grade I tumor

Tumor cells well differentiated, close resemblance to tissue of origin, and retaining some function

Grade II tumor

Tumor cells moderately or poorly differentiated

Grade III and Grade IV Tumor

Cells poorly differentiated, only remote similarity to tissue of origin, greatly increased mitosis


Recognition of tumor tissue origin is difficult, extreme variation in size and shape of tumor cells

Tumor-Node-Metastasis (TNM) System

T: Size and invasiveness of the primary tumor


N: area lymph nodes involved


M: metastasis of the primary tumor

TX

Primary tumor cannot be evaluated

T0

No evidence of tumor

Tis

Stage 1, carcinoma in situ, indicating the tumor is in a defined location with no invasion of surrounding tissues

T1, T2, T3, T4

Stage 2, primary tumor size and extent of local invasion, where do you one is small with minimal Invasion and T4 is large with extensive Invasion into surrounding organs and tissues

NX

Regional lymph nodes that cannot be evaluated

N0

Regional lymph nodes that showed no abnormalities

N1, N2, N3, N4

Stage 3, degree of lymph node involvement and spread to Regional lymph nodes, where N1is less involvement with minimal spreading and N4 is more involvement with extensive spreading

MX

Distant metastasis that cannot be evaluated

M0

No evidence of metastasis

M1

Stage 4, presence of metastasis

Squamous cell carcinoma

Predisposing factors for this including exposure carcinogens hereditary diseases such as xeroderma pigmentosum and albinism, and presence of lesions such as actinic keratosis and Bowen disease

Cellulitis

Diffuse acute infection of skin and subcutaneous tissue

Chloasma

Pigment discoloration of skin, usually yellowish brown patches or spots

Comedo

Typical small skin lesion of acne vulgaris, caused by accumulation of keratin, bacteria, and dried sebum plugging an excretory duct

Dermatomycosis

Fungal skin infection

Ecchymosis

Skin discoloration, irregularly formed hemorrhagic area with blue to black to greenish or yellow, bruise.

Eczema

Chronic inflammatory characterized by erythrma, papules, vesicles, pustules, scales, crusts, and scabs accompanied by pruritis. Atopic dermatitis.

Erythema

Redness of skin caused by swelling of capillaries

Eschar

Dead matter sloughed off, especially after a burn

Impetigo

Bacterial skin infection characterized by isolated pustules that become crusted and rupture

Lentigo

Small brown macules especially on face and arms brought on by sun exposure, usually in middle-aged or older people

Keratosis

Secondary of epidermis or any horny growth on skin, such as a callus or wart.

Pediculosis

Lice infestation

Petechia

Minute pinpoint hemorrhage under the skin. Smaller ecchymosis

Pruritis

Intense itching

Psoriasis

Chronic skin disease characterized by circumscribed red patches covered by thick dry silvery adherent scales caused by excess development of basal layer of epidermis

Tinea

Fungal skin infection. Also ringworm

Scabies

Contagious skin disease transmitted by mites, commonly through sexual contact

Purpura

Any type of bleeding disorders characterized by Hemorrhage into the tissues, particularly beneath the skin or mucous membranes

Urticaria

Allergic reaction of the skin characterized by eruption of pale red elevated patches called wheals or hives

Verruca

Warts

Vitiligo

Localized loss of skin pigmentation characterized by milk white patches

Fulguration

Tissue destruction through high-frequency electric current

Photodynamic therapy

Procedure in which cells selectively treated with an agent called a photosensitizer are exposed to light to produce a reaction that destroys the cells. Used to treat cancer actinic keratosis and macular degeneration

Mohs

Layers of cancer containing skin progressively removed and examined until only cancer-free tissue remains

Culture and sensitivity C&S

Laboratory tests to identify sensitivity of a bacterium to antibiotic drugs