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17 Cards in this Set
- Front
- Back
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allogenic
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in transplantation denotes tissue, particularly stem cells from either bone marrow or blood, that are from the same species but are antigenically distinct
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anergy
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immunodeficient condition characterized by lack of or diminished reaction to an antigen or group of antigens
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antigen
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a substance that elicits an immune response
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autoimmunity
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an inappropriate immune reaction to self-proteins; the immune system no longer differentiates self from nonself with respect to these substances
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autosomal recessive disease
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disorders that result from mutations of two gene pairs (homozygous) on a chromosome
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cell-mediated immunity
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immunity that is initiated through specific antigen recognition by T lymphocytes, macrophages, and natural killer cells
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cytokines
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soluble factors secreted by white blood cells and a variety of other cells in the body that act as messengers among cells of the immune system, endocrine, and nervous systems
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gene therapy
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treatment of genetic disorders by replacing or repairing defective or missing genes with normal genes
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heterozygous
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the presence of one recessive and one dominant allele at a given chromosomal location
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homozygous
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a trait produced by identical or nearly identical alleles at a given chromosomal location
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human leukocyte antigens
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system that consists of a series of linked genes that occur together on the sixth chromosome in humans and is used to assess tissue compatibility
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humoral immunity
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antibody-mediated immunity
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hypersensitivity reaction
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the result of an immune system that is overreactive against foreign antigens or fails to maintain self-tolerance, resulting in tissue damage
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immunocompetence
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the ability of the body's immune system to identify and inactivate or destroy foreign substances
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immunodeficiency
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inadequate protection of the body by the immune system
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immunosuppressive therapy
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therapy that inhibits immune function and is prescribed for patients to treat autoimmune disorders and to prevent transplant rejection; immunosuppression is a serious side effect of cytotoxic drugs used in cancer chemotherapy
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monoclonal antibodies
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homogeneous populations of identical antibody molecules produced by specialized tissue cell culture lines
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