• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/134

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

134 Cards in this Set

  • Front
  • Back
A metabolic disease characterized by hyperglycemia due to the bodies inability to produce or correctly use insulin?
Diabetes (definition)
Can't convert food to energy which leaves the cells starved for energy and too much glucose in the blood?
Diabetes
Juevenile Onset DM
Insulin Dependent DM (IDDM)
Type I Diabetes
Adult Onset DM
Non-insulin Dependent DM (NIDDM)
Type II Diabetes
What produces hormones that are essential for the body to break down and use CHO, protein, and fat?
Pancreas
Cells produced by the pancreas in cluster groups are called?
The islets of Langerhans.
This type of cell produces glucagon and prevents glucose from falling below 70?
Alpha Cells
This type of cell produces insulin and moves glucose across cell membranes and into cell?
Beta Cells
This type of cell produces somotostatin?
Delta Cells
It's main function is to allow active transport of glucose into the cell through the cell membrane?
Insulin
Measures blood glucose in patient that hasn't eaten in a least 8 hours, most accurate in the morning, preferred due to low cost and convenience?
FPG (fasting plasma glucose)
99mg/dl or below
Normal FPG
100-125mg/dl
Pre-diabetic FPG
126mg/dl or above
Diabetic FPG
Persons fast for 8 hours before the test, plasma glucose is checked immediately before and two hours after client drinks a liguid containing 75 grams of glucose dissolved in water. If client has level >200mg/dl, test must be repeated on a different day to confirm diabetes diagnosis?
OGTT (Oral Glucose Tolerance Test)
139 mg/dl and under
Normal OGTT
140-199 mg/dl
Pre-diabetic OGTT
200 mg/dl and above
Diabetic OGTT
> 200 mg/dl and the presence of symptoms that would indicate diabetes?
Any random blood glucose level.
Polyuria (increased urination)
Polydipsia (Increased thirst)
Polyphagia (increased hunger w/unexplained weight loss)?
The three classic symptoms of diabetes or the 3 P's.
Other symptoms can include fatigue, blurred vision, and sores that do not heal.
Diabetes
How will a doctor confirm diabetes after noting the signs and symptoms?
Patient will come back the next day for either an FPG or an OGTT.
Autoimmune disorder from destruction of the beta cells?
Type 1 Diabetes
Absolute deficiency of insulin?
Type I Diabetes
Onset usually in children and adolescence, but can occur at any age?
Type I Diabetes
Genetic predisposition, can be triggered by viruses or chemicals in genetically predisposed clients?
Type I Diabetes
Must have exogenous insulin to survive?
Type I Diabetes
Will experience hyperglycemia and ketosis?
Type I Diabetes
Develops rapidly, frequent urination, excessive thirst, excessive hunger, weakness and fatigue, drowsiness, irritability, changes in vision, fruity breath, N/V, unexplained weight loss?
Signs and Symptoms of Type I Diabetes
Usually preventable and more common?
Type II Diabetes
Has an insulin deficiency but has some endogenous production?
Type II Diabetes
Cellular resistance to effect of insulin?
Type II Diabetes
Can occur at any age, frequently seen in middle age, but incidence in overweight children are increasing, pt's are usually obese and have a family hx?
Type II Diabetes
Non-ketotic Diabetes?
Type II Diabetes
Gradual hyperglycemia, may exist years before symptoms are noted, usually are found when the pt is seeking tx for another medical problem?
Type II Diabetes
Obesity, family hx, sedentary lifestyle, race, hx of large babies, gestational diabetes, HTN, HDL<35, Triglycerides>250, Metabolic syndrome?
Risk factors for Type II Diabetes
Insulin resistance, apple shaped body, low activity, increased BP, increased blood fat, gene-environment interactions, high risk diabetes and cardiac disease?
Metabolic Syndrome
Polydipsia, polyuria, blurred vision, fatigue, frequent vaginal yeast infections, poor wound healing, parasthesias, impotence?
Symptoms of Type II Diabetes
NO weight loss or fruity breath?
Type II Diabetes
Blood test with no special prep to determine the average blood glucose levels over the last 2-3 months?
Hbg A1C (Glycosylated hgb)
Monitors the amount of glucose attached to hgb molecule?
Hgb A1C
Used to determine effectiveness in treatment plan and at initial dx should be done at least q 3-6 mo.?
Hgb A1C
Has been associated with a reduction of microvascular and neuropathic complications?
Lowered A1C
Goal is <7% in diabetic pt's?
Hgb A1C
5% in non-diabetic pt's?
Normal A1C
Due to the mother's inability to produce enough insulin, an increased risk of complications, controlled with diet and insulin, person is at higher risk for type II if the ideal body weight is not maintained, 5-10% develop Type II diabetes?
Gestational Diabetes
First prenatal visit screen for hight risk pt's?
OGTT for pregnant women
Performed during 24-28 weeks, is a 2 hr test?
GTT (Glucose Tolerance Test)
Done to confirm gestational diabetes?
OGTT
Drinks a high glucose load after fasting and blood glucose samples are taken at hourly intervals every 4 hours?
OGTT
Two positive OGTT equals a diagnosis of?
Gestational Diabetes
Preprandial plasma glucose (fsbs before meal)?
70-130 mg/dl
Postprandial plasma glucose (fsbs after meals)?
<180 mg/dl
HgbA1C's should be what in diabetic pts?
<7%
BP should be what in diabetic pts?
<130/80
LDL's should be what in diabetic pts?
<100mg/dl
HDL's should be what in diabetic pts?
>40 mg/dl
Blood sugars between 110-126, will develop type II diabetes unless they change their lifestyle, should be screened anually?
Pre-diabetics
Insulin therapy, CHO controlled diet, exercise, checking blood sugar, sick day management, ketone checks in urine, foot care, eye care?
Tx for type I diabetes.
1st try diet modification, exercise and weight loss, if that doesn't work use oral mediations such as insulin?
Tx for type II diabetes.
High in fiber, lean protein, low fat dairy, vegetables and fruit, and samll amounts of sweets in moderation?
A diabetic diet
210 grams of CHO per day?
What the diabetic should consume in carbohydrates.
Oral

Supports hepatic glucose, decreases intestinal glucose absorption, increases tissue response to insulin, does not increase insulin production (so no chance of hypoglycemia), risk of lactic acidosis if poor renal function, do not use if vomiting, x-ray dye or surgery?
Oral

Biguanide: Glucophage or metformin.
Oral

Delays CHO digestion and glucose absorption, after meal glucose peaks are not as high, give with first bite of each meal, bloating flatulence, and diarrhea, hypoglycemia, gradually increase dose to minimize side effects?
Oral

Alpha-Glucosidase Inhibitors: Acarbose (Precose), Miglitol (Glyset)
Oral

Makes muscle cells more sensitive to insulin, decreases glucose from the liver, need to watch liver function very carefully, teach client to report brown urine, do not use if patients have heart failure (Class III-IV), can increase fluid retention, no hypoglycemia risk, can make birth control ineffective?
Thiazolidinediones: Rosiglitazone (Avandia) and Prioglitazone (Actos)
Oral

Promotes insulin secretion by the pancreas, give within 1-30 minutes of meal, do not give if meal skipped, hypoglycemia, headache?
Oral

Meglitanides: Repanglinide (Prandin), Nateglinide (Starlix)
Oral

Blocks enzyme known as dipeptidyl peptidase IV-thereby prolonging the stimulation of insulin production, give daily with or without food, check renal function before beginning therapy, headache, upper repiratory infections?
Oral

DDP-4 Inhibitor: Sitagliptin Phosphate (Januvia)
Humalog (Lispro)?
Rapid acting injectable insulin
Novalog (Aspart)?
Rapid acting injectable insulin
Apidra (Glulisine)
Rapid acting injectable insulin
Regular insulin?
Short acting injectable insulin
NPH?
Intermittent acting injectable insulin
Lantus (Glargine), Levemir (Detemir)?
Long acting injectable insulin
Hypoglycemia and Hyperglycemia are what in diabetes?
Complications of diabetes.
Blood glucose <60?
Hypoglycemia
Insulin errors, diet, exercise, alcohol and drugs?
Causes of hypoglycemia
Happens most commonly at insulin's peak?
Hypoglycemia
These pt's should carry hard sugar candy or glucose tabs always?
Hypoglycemia pt's
Reactions such as headache, hunger, tremors, diaphoresis, apprehension, pallor?
Mild S/S of hypoglycemia
Reactions such as irritability, trouble concentrating, behavioral changes, slurred speech, and difficulty walking?
Moderate S/S of hypoglycemia
Reactions such as disorientation, loss of consciousness, inability to respond, and seizures?
Severe S/S of hypoglycemia
Give a form of quick sugar 10-15 gm for a mild reaction, 2-4 glucose tablets, 1/2 cup of orange juice (if no renal problems) 4-5 pieces of hard candy, 6 oz. regular pop, or 2 tbsp of cake icing?
Treatment of hypoglycemia
Use glucose paste, subcutaneous glucagon or D5O IV push.
Treatment of hypoglycemia if pt can't swallow.
Stay with the person and recheck glucose in 10-15 minutes, if still low then treat again. If not time for meal, take a snack with protein. Use episode to teach and to find out what wen wrong and correct it. Avoid frequent episodes. May need to adjust meds if occuring frequently?
Treatment of hypoglycemia
Swelling of fat tissue from injection of insulin. Dimpling or bumpy scar tissue?
Lipodystrophy
Injection of cold insulin, failure to rotate sites, allergic reaction, uneven insulin absorption?
Causes of Lipodystrophy
Hypoglycemia at night (undetected) and body responds with epinephrine and glucagon so patient wakes with an elevated sugar?
Somogyi Effect (Rebound Hyperglycemia)
Check 3AM sugar and sleep hapits of pt, if 3AM sugar is low, then decrease evening insulin dose or increase food intake at bedtime?
Somogyi Effect (Somogyi Effect/Snack)
Nighttime release of growth hormone, cortisol, and catecholamines, elevated glucose at 0500-0600?
Dawn Phenomenon
More insulin for the overnight period, eat bedtime snack with protein and limit carbs, exercise later in the evening, eat breakfast, check 3AM glucose?
Dawn Phenomenon (Dawn/Do)
Result of undiagnosed type I diabetes?
DKA (Diabetic Ketoacidosis)
Too little insulin, too much food intake, stress, illness (with vomiting can occur in just a few hours), infection, can cause coma and death if not treated, onset is usually slow (4-10 hours)?
Causes of DKA (Diabetic Ketoacidosis)
Insufficient insulin results in an inability to metabolize glucose, body breaks down fat and muscle for fuel, fat burns for energy resulting in ketosis, ketone bodies accumulate in the blood, hydrogen exchanged for potassium, elevated serum osmolality created by large volumes of glucose in the serum?
DKA (Diabetic Ketoacidosis)
Elevated glucose levels in the renal tubules: precipitate osmotic diuresis, with losses of water, Na+, Cl-, and K+?
DKA (Diabetic Ketoacidosis)
Inadequate volume replacement followed by significant dehydration and electrolyte deficits?
DKA (Diabetic Ketoacidosis)
Pulmonary and renal compensatory mechanisms triggered by these deficits?
DKA (Diabetic Ketoacidosis)
Lungs: attempt to eliminate excess acids through deep and rapid respirations (Kussmaul's respirations) to compensate for increase in ketones?
DKA (Diabetic Ketoacidosis)
Kidneys: attemp to increase acid excretion in urine?
DKA (Diabetic Ketoacidosis) ketonuria
Thirst or a very dry mouth, frequent urination, high blood glucose (sugar) levels, high levels of ketones in the urine, constantly feeling tired, dry or flushed skin, N/V or abdominal pain, a hard time breathing (short, deep breaths), fruity odor on breath, a hard time paying attention, or confusion?
Symptoms of DKA (Diabetic Ketoacidosis)
Elevated serum glucose (>300 mg/dl), symptoms of FVD (increased HR, Low BP, etc.), Increaed serum ketone level, positive urine ketones (moderate to severe), ABG's (Metabolic acidosis), Labs (initially normal to hyperK+ to hypoK+, elevated BUN due to dehydration)?
Diagnostic findings of DKA (Diabetic Ketoacidosis)
Aggressive fluid replacement and K+ replacement, regular or humalog insulin IV bolus, then a regular insulin gtt, blood sugar Q1hr, when fsbs <200-250, start IVF with D5NS, watch electrolytes especially K+, monitor heart, neuro and renal function, teaching to prevent future problems?
Treatment of DKA (Diabetic Ketoacidosis)
HHNK typically occurs in what type of diabetes?
Type II Diabetes
Severe hyperglycemia (>600 mg/dl, has some insulin present, but not enough to metabolize glucose, characterized by hyperglycemia, hyperosmolarity (350-400), and osmotic diuresis, NO ketosis and ketonuria present, symptoms of severe FVD, dry flushed skin, may have fever, can have seizures or coma if not treated, caused by illness, stress, and infection?
Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNK)
IV fluid administration (6-20 liters of fluid in first 24-48hrs), IV bolus of regular or rapid acting insulin, then insulin gtt with regular insulin, fsbs hourly, electrolyte replacement therapy, change IVF to D5NS once fsbs<250 to prevent hypoglycemia, watch electrolytes especially K+, monitor heart, neuro and renal function, teaching to prevent future problems?
Treatment of Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNK)
Hot & Dry?
Sugar High
Cold & Clammy?
Need some candy
Lipid disorders, hypertension, increase atherosclerosis affects brain, heart earlier onset of stroke and CAD, PVD 5 times more likely to get gangrene, CHF 6 times more likely, all these lead to earlier mortality and morbidity?
Macrovascular complications
Genetic factors, age, and duration of diabetes?
Non-treatable factors of Macrovascular complications.
Smoking, HTN, Hypercholesterolemia, Hypertriglyceridemia, Hyperglycemia, Hyperinsulinemia, Obeisty?
Treatable factors of Macrovascular complications.
Problems with thickening of the capillary basement membrane, leading cause of blindness causes retinal hemorrhage and scar tissue, treated with laser, must see opthalmologist yearly, eyes must by dilated to test, more likely to develop glaucoma, increased risk of cataracts?
Retinopathy
Damage of glomerular capillaries, thickened basement membrane and leakings out of large protein molecules, leading cause of renal failure, starts shortly after diagnosis?
Nephropathy
Check kidney levels and 24 hour urine, usually will find consistent protein in the urine 3-7 years from dialysis, if microalbuminuria you are 10-20 years before dialysis?
Nephropathy
Tight glucose control, HTN control, watch for kidney infections, monitor creatinine clearances, low protein diet, limit exposure to IV dyes and other meds that could harm the kidneys, ACE drugs should be used cautiously in renal failure due to potential for increased K+?
Nephropathy prevention
Sensory paresthesias, burning pain, weakness and decreased sensation, can be an early symptom in type II diabetes, creates problems with foot ulcers as sores are not detected, teach to inspect feet daily, do not go barefoot, podiatrist to clip toenails, see Dr. for sores or cuts on feet?
Neuropathy
Affects involuntary body functions, including heart rate, blood pressure, perspiration, digestion and other processes such as: Orthostatic hypotension, urinary problems, sexual difficulties, gastroparesis, sweating abnormalities, sluggish pupil reaction, lack of warming signs of hypoglycemia?
Autonomic Neuropathy
Do not skip insulin or meds, stress of illness could require more insulin, check blood sugar often, at least q 4h and take your insulin or meds as ordered, take 10-15 g CHO every hour if can not eat, call doctor if diarrhea and vomiting >4 hrs, call if ketones in urine are moderate to large, call for fsbs>300 mg/dl?
Sick Day Instructions
Good control prior, stress may cause hyperglycemia, can have half daily dose, usually do not hold lantus, frequent sugars and insulin accordingly, keep<150 to promote wound healing, watch for healing problems, CV status, neurogenic bladder?
Surgery precautions
Less than 80 before meals?
Finger stick blood sugar goal.
Less than 6-7%?
HbgA1C every three months goal, every 6 months with good control.
Less than 128/74?
Blood pressure goal for diabetic patient.
Needs a lipid profile yearly?
The diabetic pt.
Urine for microalbumin yearly to r/o renal damage?
The diabetic pt.
Dilated eye exam opthalmologist yearly?
The diabetic pt.
Foot exams daily per self and per clinician every 6 months to a year?
The diabetic pt.
Shaking, tachycardia, sweating, anxious, dizzy, hunger, impaired vision, weakness, fatigue, headache, irritability?
S/S of hypoglycemia (low blood sugar)
Too little food, too much insulin or diabetes medicine, or extra exercise?
Hypoglycemia
Sudden and may progress to insulin shock?
Onset of hypoglycemia
Below 70 mg/dl, normal range 70-115 mg/dl?
Hypoglycemia
Orange juice, milk, hard candies, test your blood sugar, eat a snack within 30 minutes, you may need to call your doctor?
What to do for hypoglycemia.
Thirst, frequent urination, dry skin, hunger, blurred vision, drowsiness, nausea?
S/S hyperglycemia
Too much food, too little insulin, illness or stress?
Causes of hyperglycemia
Gradual, may progress to diabetic coma?
Onset of hyperglycemia
Blood sugar above 200 mg/dl, acceptable range: 115-200 mg/dl?
Hyperglycemia
Test blood sugar, if over 250 mg/dl for several test CALL YOUR DOCTOR?
What to do in hyperglycemia.