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43 Cards in this Set
- Front
- Back
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Methacholine |
Diagnosis of Bronchospasms |
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Carbachol
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glaucoma Eye Surgery |
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Bethanechol
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urinary retention and atony of muscles |
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Pilocarpine
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0.5% solution in treatment of Glaucoma
muscuranic-specific
S.E.: sweating, salivation & gastric secretion |
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physostigmine
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Glaucoma Treat overdoses of anticholinergics Investigational in Alzheimers
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neostigmine
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Post surgical atony of muscles improve myasthenia gravis, ptosis and diplopia
longer DOA than Physostigmine not affected by pH |
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Pyridostigmine |
Tx of myasthenia gravis
1/5th as toxic as Neostigmine
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edrophonium |
Diagnosis of myasthenia gravis |
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ambenonium |
Tx of Myasthenia Gravis (alternative to neostigmine or pyridostigmine) |
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demacarium
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Tx of open/wide angle glaucoma |
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tacrine
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Alzheimer's |
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donepezil
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Alzheimer's; dementia |
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rivastigmine
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Alzheimer's |
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Isofluorophate |
Glaucoma |
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echothiophate |
Glaucoma |
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atropine |
Mydriatic/cycloplegic agent duration refraction studies in iritis and uveitis
suppress toxicity from organophosphate |
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scopolamine |
Motion sickness |
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Homatropine
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Mydriatic/cycloplegic property |
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ipratropium
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Asthma, COPD |
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Tiotropium |
Asthma, COPD |
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Clidinium |
Antispasmodic & antisecretory
with chlordiazepoxide (tranquilizer) for peptic ulcer and GI secretory disease |
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Dicyclomine |
antispasmodic effect on GIT smooth muscle irritable bowel syndrome
affinity for M1 and M3 > M2 & M4 |
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Glycopyrrolate |
Hyperhidrosis and sialorrhea
with Neostigmine to balance heart rate
asthma &COPD
affinity for M1 > M2 & M3
In high doses, can block gang. & NMJ receptors |
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Propantheline |
Antispasmodic & antisecretory |
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Diphenhydramine |
Antihistaminic agent; allergies
alleviates some PD symptoms
S.E: drowsiness & CNS depression |
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Benztropine |
Management of PD
minimizes sialorrhea, oculogyric crisis & muscular cramps
as potent as atropine
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Biperiden |
Useful for idiopathic and induced PD
alleviates akinesia, rigidity and tremors
spastic disorder e.g. spinal cord injury, cerebral palsy & multiple sclerosis
more affinity for M1 |
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Procyclidine |
improves rigidity or bradykinesia |
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Trihexyphenidyl |
All forms PD
reduces mydriasis and sialorrhea
Binds M1
half of atropine's potency - safe! |
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Isopropamide |
peptic ulcers
long DOA |
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Darifenacin |
antidiuretic
M3 selective |
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Ethopropazine |
PD; antidyskinetic
improves tremors, sialorrhea, rigidity & oculogyric crisis |
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Papaverine |
Raynaud's Disease
lacks potency
inhibits hydrolisis of cAMP & cGMP
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Nicotine |
Stimulant at low dose
Gang. Blocker @ high dose |
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Hexamethonium |
Hypertension
strong gang. blocker; weak curariform activity
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Decamethonium |
Hypertension
Weak gang. blocker; strong curariform activity |
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Trimethaphan |
Hypertension
administered by IV |
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Mecamylamine |
Hypertension
absorbed in GIT
Both comp. and non-comp. inhibitor
S.E. orthostatic hyprtension
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Tubocurarine |
Adjunct in gen. anesthesia
administered by IV
reversed by neostigmine and edrophonium |
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Atracurium |
skeletal muscle relaxant for short surg. procedures
2.5X as potent as tubocurarine
reversed by pyridostigmine, neostigmine and edrophonium |
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Doxacurium |
skeletal muscle relaxant surg. procedures > 90 mins |
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Pancuronium |
skeletal muscle relaxant DURING surgery
Effect increased by gen. anestetics
acts on nicotinic receptor and in ion channel
5X as potent as tubocurarine |
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Succinyl |
skeletal muscle relaxant DURING surgery
used in intratracheal intubation and endoscopic procedures
unstable in alkaline solution (should not be mixed with thiopental sodium)
Effect not reversed by AChE inhibitors |
