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15 Cards in this Set
- Front
- Back
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cholinergics divided into two categories
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direct acting cholinergic agonist
indirect-acting cholinesterase inhbitors |
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what's direct acting used for
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decrease intraocular pressure in open angle glaucoma
initiate smooth muscle in bowel and urinary tract after sx tx of AD |
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indirect cholinergic used for
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inhibit destruciton of ach
myastemia gravis glaucoma reversal of neuromuscular blockade initiation of sm muscle activiy following sx AD - mainly |
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where does choline come from
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serine in diet
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agents affecting storage of Ach
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vesamicol
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botulism primary site of action is on the ---- nerve terminal and inhibits relaase of ---
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cholinergic
Ach |
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tetrodoxtoin blocks ----
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Na
se: cv and resp |
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saxitoxin caused by
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karenia brevis
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brevetoxins are depolarizing substances that open voltaage gated ---- ion channels
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Na
leads to uncroled Na reflux upper resp tract irritation, nasal congestion, cough, wheezing, sob |
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M1 is located in:
M2: M3: M4: |
M1: neural
M2: cardiac M3;: glandular M3 inhibits camp thru G1 and acts on K |
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used to diagnose asthma
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b methyl choline
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bethanechol chloride resistant to -----
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hydrolysis
so it hangs around longer |
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bethanechol is --- so it's permanently charged so no BBB
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quaternary
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behtanechol only activates
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M1, 2, 3, 5 in periphery
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uses of musarinic
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peptic ulcers
dilate pupils paralyze ciliary muscle control asthma |
