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22 Cards in this Set

  • Front
  • Back
What are the five most important thing for a patient who is facing death?
Comfort

Sense of control / dignity

Relieving burden on loved ones

Strengthening and completing relationships with significant others

Avoiding prolongation of dying
What is the pneumonic and the meaning of the letters in regards to taking a pain history?
P lace: Where?
A mount: How much?
I ntensifiers: Worse?
N ullifiers: Better?
E ffects: Medication effect/side effect? Effect on QOL?
D escription: How does it feel?
What are the various types of pain?
Nociceptive
Somatic
Inflammatory
Visceral

Neuropathic

Mixed

Acute, chronic, chronic with acute
What is the pneumonic and its meaning in regards to the rational approach to pain management?
T reat treatable causes
O ptimize analgesic medications
N on pharmacological modalities
I nvasive procedures
What are the various non-pharmacologic means of dealing with pain?
Heat and cold
Massage
Physical Therapy
TENS
Distraction/Relaxation/Music Therapy/Meditation
Acupuncture/Energy Work
If a patient is suffering from constant pain, it is best to do what in regards to their opiods?
If patient is taking a short acting opioid, make sure to prescribe a sustained release opioid to provide constant 24 hour pain control.
A patient who is tolerant to the effect and side effects of one opioid may not be equally tolerant to the effects and side effects of another opioid.
Incomplete Cross Tolerance
This is an example of how to conver to a new opioid.

Decrease equi-analgesic dose by 1/3 to 1/2 because of incomplete cross tolerance

240 mg oral morphine – 80mg = 160 mg oral morphine/24 hours

New dose: SR Morphine 80mg po q12h
Decrease equi-analgesic dose by 1/3 to 1/2 because of incomplete cross tolerance

240 mg oral morphine – 80mg = 160 mg oral morphine/24 hours

New dose: SR Morphine 80mg po q12h
What are three common sustained released opioids?
Oxycodone SR 80 mg q12h
Morphine SR 80 mg q12h
Duragesic 125mcg/hr patch q72h
How do you determine the PRN dose?
Each PRN dose should equal
10-15% of the 24 hour dose of sustained-release or transdermal opioid
What is used to manage neuropathic pain?
Opioids-particularly methadone
Adjuvants: Tricylic antidepressants-amitriptyline, nortriptyline, desipramine (10-150 mg qhs) Anticonvulsants-gabapentin 300 mg qhs to 300-900 mg TID, clonazepam 0.5-1.0 mg TID, carbamepine 200 mg po BID to QID
Lidocaine patches (Lidoderm 5%), intravenous lidocaine; Mexilitine
Non-pharmacologic-heat, ice, hypnosis, PT, massage, cognitive-behavioral
Corticosteroids
Pharmacokinetic Considerations:

Morphine is the standard
opioid
Active metabolite

Hydromorphone (Dilaudid)
Active metabolite

Methadone
Long and variable half life necessitates careful monitoring for sedation

Fentanyl
Liphophillic

Codeine
Analgesic ceiling effect
Morphine is the standard opioid
Active metabolite

Hydromorphone (Dilaudid)
Active metabolite

Methadone
Long and variable half life necessitates careful monitoring for sedation

Fentanyl
Liphophillic

Codeine
Analgesic ceiling effect
How do you TX constipation in a pain patient?
Tx prophylactically:
-stool softener (docusate 100mg BID),
-laxatives (senna 2 tablets or 10-15 ml syrup BID); lactulose or sorbital 15 ml BID, Miralax 17-30 gm po
-bisacodyl (Dulcolax) 10 mg suppository PR
-sodium phosphate or oil retention enema
What are some side affects of opiates?
Respiratory depression

Sedation:
-address other causes
-consider psychostimulants, methyl-
phenidate (Ritalin)

Urinary retention-stop tricylic antidepressants

Pruritus-antihistamine (diphenhydramine 25 mg QID)
How do you TX opiod induced constipation?
Tolerance does not develop

Aggressively prophylactic with scheduled doses of
Stool softener
Docusate
Mild stimulant laxatives
Senna
Miralax
Lactulose
Biscodyl

Avoid bulk forming laxatives like Metamucil (phsyllium), Citrucil (methylcellulose)

BeneFiber maybe reasonable option if patient wants to continue taking fiber
What are signs that death is near?
Sleeping more
Less responsive
Concentrated, low volume urine
Coolness of hands, arms, feet, legs
Mottling of skin
Loss of bowel and bladder control
Changes in breathing pattern
Withholding or withdrawing artificial hydration/nutrition is ethically justified if such interventions are ?
Ineffective or futile
Harmful
Disproportionately burdensome

Slowing of GI function leads to bloating, discomfort that worsens with artificial feeding

Circulation slows leading to accumulation of fluid in lungs, abdomen, limbs which may worsen with IV fluids
What are the changes in cardiac function before death?
Pulse may increase; blood pressure decreases
Accumulation of fluid in lungs, abdomen, limbs
Limbs feel cool and look bluish; mottled
Diaphoretic
Tachycardia should not be used as a sign of pain
As circulation to kidneys decrease before death, what may be seen?
Less urine; more concentrated
Failure to rid body of metabolic wastes leading to delirium
Lethargic or agitated state that develops over hours to days characterized by
Disorientation
Memory deficits
Inability to focus or pay attention
Occurs in up to 85% of patients at EOL
Reversible in up to 50%
Symptomatic treatment with medications that may be sedating
Delirium
What changes in respiration are seen before death?
Respirations may increase
Increasing muscle weakness leading to inability to cough, clear secretions (death rattle)
Respirations become irregular; sometimes gasping or “agonal”, apneic periods
Reassure family these are not a sign of patient distress
SUMMARY:

Palliative Care is an approach to care that should be available to all patients with life threatening illness

Skilled pain management is a foundation of palliative care and can be effectively applied with a few simple guidelines

Understanding the syndrome of imminent death and educating families on what to expect can be very helpful for them
SUMMARY:

Palliative Care is an approach to care that should be available to all patients with life threatening illness

Skilled pain management is a foundation of palliative care and can be effectively applied with a few simple guidelines

Understanding the syndrome of imminent death and educating families on what to expect can be very helpful for them