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31 Cards in this Set

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This is a chronic inflammatory disease that presents with progressive spine stiffness. It is most often seen in young adults with an onset of 20-30 y.o., inflammation around enthesis causing fibrous or bony bridging of joints is seen. It responds to NSAIDS.
Ankylosing Spondylitis
This occurs at the intervertebral disc margins. The apophyseal joint capsue insertion on the bone is affected, as well as teh ligamentous insertions on the spine.
Ankylosing Spondylitis
What are the primary sites of disease in ankylosing spondylitis?
Sacroiliac Joints

Apophyseal Joints
Many patients with ankylosing spondylitis are positive for this genetic marker?
HLA-B27
What are two major signs of ankylosing spondylitis?
Pain radiates to gluteal region and proximal posterior thigh.

Morning back stiffness that improves with activity, sometimes this pain will disrupt sleep.
This is the most frequent extraarticular manifestation of ankylosing spondylitis?
Acute Anterior Uveitis
How does acute anterior uveitis, associated with ankylosing spondylitis, present?
Severe eye pain, redness, photophobia, blurry vision, increased lacrimation. Immediate referral to ophthomologist is required.
What is a physical exam test that can be used to diagnose ankylosing spondylitis?
Schober's Test
What physical exam findings will you have with ankylosing spondylitis?
Pain with palpation of the following:
SI joint
Spinal/paraspinal region
Ischial tuberosities
Iliac crests
Costovertebral/Costochondral junctions
Achilles tendon/Plantar fascia

Reduced lateral flexion, extension, and rotation of the back.
What is the most prevalent sign of ankylosing spondylitis on X-Ray?
Bamboo Spine appearance
What is the TX for ankylosing spondylitis?
NSAIDS - start with period NSAID use but may need to progress to continual therapy.

Replace NSAIDs with COX-2 Inhibitor (celecoxib) if NSAID unsuccessful
This is a narrowing of the spinal canal, compressing the nerve roots. Primarily effects the lumbar region but can effect any region of the spinal column. Effects mostly older people. Is characterized by back pain and "neurogenic claudication".
Spinal Stenosis
There are two types of Lumbar Spinal Stenosis, what are they?
Acquired

Congenital
This is the most common type of lumbar spinal stenosis, it is caused by degenerative disease, trauma, post-spine surgery, metabolic or endocrine disorders, Paget's disease.
Acquired Lumbar Spinal Stenosis
This is lumbar spinal stenosis that presents at an early age (30-40 y.o.) and is caused by achondroplasia or is idiopathic.
Congenital Lumbar Spinal Stenosis
The signs and symptoms of this are as follows:

Neurogenic Claudication

Aching pain originating in the low back, that radiates to the buttocks and upper legs. It worsens with walking and standing. Relief with sitting, lying or bending forward.
Lumbar Spinal Stenosis
With this you can see leg neuropathy such as numbness, parasthesias, weakness, "spaghetti legs", wide gate "walking like a drunk soldier".
Lumbar Spinal Stenosis
What imaging studies are used for diagnosing Lumbar Spinal Stenosis?
MRI

CT Myelography good alternative in patients unable to have MRI
What are the non surgical TX for spinal stenosis?
Physical Therapy
Weight Loss
NSAIDS
Epidural Injections
What are the surgical options for lumbar spinal stenosis?
Laminectomy - Removal of lamina and spinous process adjacent to impinged nerve.

Laminotomy - Only a portion of the lamina is removed.
The key characteristics are that it produces a siciatic type pain, there are clear physical exam findings that suggest disc impingement on nerve roots. Most common site for this is at L4-L5 or L5-S1.
Herniated Disc Disease
With this there is a degeneration of the outer layers of the intervertebral disc, weaking of the anulus fibrosus, and tearing and fissure formation of the anular layers.
Herniated Disc Disease
This usually has a distinct time of onset, ie it is not gradual. There is a sharp, burning, stabbing pain that radiates down posterior or lateral aspect of the leg to below the knee. Often numbness and tingling. Pain worsens with sitting or bending, relief with standing or lying.
Herniated Disc Disease
This is what a person with herniated disc disease does when they are in pain and want to try to avoid impinging a nerve root.
Sciatic list
What are the physical exam findings with herniated disc disease?
Difficulty heel walking

Decreased SAR with great toe dorsiflexion

Straight leg raise test - pt feels pain at less than 80 degrees of leg being raised, when foot is dorsiflexed there is more pain.
What is the gold standard for imaging herniated disc disease?
MRI
What is the TX for herniated disc disease?
Conservative Therapy - Bed rest 2-7 days, exercise - strengthening of abdominal and back muscles, weight loss. Injections - lidocaine at trigger points or areas of localized pain.
This results from a compression of cauda equina nerve roots by a lesion:
Traumatic Injury
Lumbar disc herniation
Abscess
Spinal epidural hematoma
Tumor
Late stage ankylosing spondylitis

Presenting symptoms:
Non specific back pain
Urine or stool incontinence
Saddle paresthesia
Cauda Equina Syndrome
What are the exam findings associated with cauda equina syndrome?
Pain with palpation of the lower back

Diminished or absent DTRs

Loss of light touch in perineum

Poor anal sphincter tone
What imaging is best to diagnose cauda equina syndrome?
CT scan
What is the best TX for cauda equina syndrome?
Emergency surgical removal of impinging lesion

Permanent nerve damage can ensue if not corrected surgically