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18 Cards in this Set

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For euvolemic men, what does the hemoglobin concentration have to be?
< 13 g/dL
For euvolemic women, what does the hemoglobin concentration have to be?
<12 g/dL
What are three conditions that can cause anemia in the elderly?
malignancy, infection, and gastrointestinal bleeding.
What are the initial tests to diagnose anemia?
Hemoglobin, hematocrit, red blood cell count, reticulocyte count, WBC count and differential platelet count.
What is the MCV with normocytic anemia?
80-100 fL
What is the MCV with microcytic anemia?
< 80 fL
What is the MCV with macrocytic anemia?
> 100 fL
What are the primary causes of normocytic anemia?
Blood Loss

Early micro/macrocytic anemia
What are the primary causes of microcytic anemia?
Inadequate iron

Inadequate heme synthesis

Inadequate globin synthesis: Thalassemia minor
What are the primary causes of macrocytic anemia?
Reticulocytosis

Alcoholisim

Lipid disorders - liver disease, hypothyroidism, hyperlipidemia

Hypothyroidism

Folate or B12 deficiency
Blood loss that results in anemia is most often from?
the gastrointestinal or GU tract.
Iron deficiency imnplies chronic?
occult blood loss
This is the most common normocytic anemia, but becomes microcytic in later stages?
Anemia of chronic disease
This is normal or elevated in anemia of chronic disease as a result of inflammation or cancer?
serum ferritin
Serum ferritin reflects iron stores, and a level of ? is diagnostic of iron deficiency.
< 10 ug/L
Elderly patients are especially susceptible to fluid overload, and each unit of red blood cell transfusion should be given?
slowly over 4 hours if the patient is not acutely bleeding.
Apart from giving red blood cell transfusion, what might be necessary to give a patient?
diuretics
This includes quality of life in cancer patients undergoing chemotherapy who have anemia of chronic disease with Hgb concentrations <10 g/dL
Erythropoietin treatment