Mcb 3020C 3

Front 1

In an examination of the antimicrobial properties of a chemical substance, the exposure indicated by the arrow produced the above data with respect to viable bacterial cells and intact bacterial cells determined by microscopic counts. How would the substance be characterized?

Back 1

Bacteriolytic

Front 2

This type of drug blocks peptidoglycan cross-linking

Back 2

Beta-lactam drugs such as Penicillin or Carbapenem

Front 3

This type of drug is a growth factor analog that inhibits folic acid synthesis

Back 3

Sulfa drugs such as sulfarilamide

Front 4

This type of drug prevents successful cell division by impairing DNA replication. It inhibits the DNA gyrase enzyme.

Back 4

Quinolones such as Ciprofloxacin.

Front 5

Bacteremia is a term used to

Back 5

indicate the presence of bacteria in the blood

Front 6

Which type of vaccine is the most effecitve for inducing lifelong immmunity?

Back 6

Attenuated live vaccine

Front 7

Which of these would be a common mechanism for dissemination of antibiotic resistance genes among bacteria?

Back 7

plasmid

Front 8

Pickling is a type of food preservation utilizing

Back 8

weak acid

Front 9

Is regular flushing of urine a possible form of protection against infection by pathogens that may enter the mouth?

Back 9

No.

Front 10

The coliform organisms such as E. coli klensiella and erterobater are used as water quality indicators because

Back 10

they are found in animal intestinal tracts and can indicate fecal contamination

Front 11

Which of these is a dangerous strain of bacteria that is essentially resistant to all current antibiotics?

Back 11

Methicillin Resistant Staphylococcus Aureus. (MRSA)

Front 12

Aminoglycosides and tetracyclines all target a similar cell structure, albeit in different ways. Which structure is targeted?

Back 12

Ribosomes.

Front 13

Which of the following modes of treatment would be used to demonstrate a heat sensitive food product such as uncooked meat?

Back 13

Gamma irradiation

Front 14

Which of these organisms or groups of organisms is commonly utilized to produce fermented foods particularly using dairy foods?

Back 14

Lactic acid bacteria

Front 15

Which of these is a key component of a direst ELISA or EIA diagnostic test?

Back 15

Capture of antigens in the well of a test plate using fixed antibiotics.

Front 16

Which of these environments on the human body is typically sterile?

Back 16

lower lungs

Front 17

The coagulase enzymes and toxins produced by some staphylococcus aureus strains are considered examples of

Back 17

virulence factors

Front 18

Lymphocytes that recognize and kill infected host cells are

Back 18

cytotoxic T cells

Front 19

Cells that ingest foreign cells, digest them, and present the antigens to lymphocytes are

Back 19

macrophage

Front 20

Cells that will kill host cells not displaying any major histocompatibility complex structure

Back 20

Natural Killer cells

Front 21

Upon exposure to antigen, these cells are triggered to divide and begin producing antibodies against the antigen

Back 21

B Cells

Front 22

As a physician, you are interested in determining the presence of antibodies to a particular pathogen in a patient's serum for what primary reason?

Back 22

It indicates the patient has been infected by the pathogen and made an immune response to it. 

Front 23

Which of the following would be an enzyme that would give resistance to the type of antibiotics shown above?

Back 23

Beta lactamase

Front 24

This prokaryotic genus is the most prolific producer of antibiotics

Back 24

Streptomyces

Front 25

What is defined as: a decrease or loss of virulence to a pathogen?

Back 25

Attenuation

Front 26

What is an enzyme that is found in tears and degrades cell walls of many bacteria?

Back 26

Lysozyme

Front 27

During the process of antibody production, a foreign antigen is presented by a ___________ to a _____________ then the presenting cell is triggered to differentiate into antibody producing cells and memory cells

Back 27

B cell; T helper cell

Front 28

The bacteria that are commonly found on the skin are adapted to this environment in that they 

Back 28

are resistant to dessication (drying out) and salt

Front 29

One reason that NASBA technology is different from the PCR is

Back 29

NASBA reactions take place at a single temperature

Front 30

Which of these is a step that a bacterial pathogen usually needs to complete to be able to cause disease in a host?

 

A: Find nutrients

B: Adhere to host cells

C: Penetrate epithelial cells

D: all the above

Back 30

D: all the above

Front 31

What is the process of the destruction of infected host cells by the body's own T cells as a result of pathogen derived antigens present on the outside of the infected cell

Back 31

Cell mediated immunity

Front 32

An organism that only causes disease in the absence of normal host immune function is called an

Back 32

opportunistic pathogen

Front 33

How is it that PCR is able to detect one specific pathogen and not another bacteria or virus

Back 33

The primers used in a PCR assay target a specific gene sequence from the pathogen

Front 34

True or False? Humans are born with a normal microbial flora they acquire while in the uterus

Back 34

False

Front 35

True or False? A common indicator used in growth dependent diagnostic methods with differential media is a change in pH due to fermentation of a substance.

Back 35

True.

Front 36

True or False? The low pH of the stomach kills many potential intestinal pathogens

Back 36

True

Front 37

Enteric bacteria like E. coli are considered normal flora inhabiting the bladder in men and women

Back 37

False.

Front 38

True or False? In drinking water treatment, flocculation and filtration are used to remove protozoan cysts while chemical disinfection primarily targets bacteria and viruses.

Back 38

True.

Front 39

An example of a drug that would be selectively toxic against bacteria without harming mammalian cells could be

Back 39

an enzyme that inhibits cell wall synthesis

Front 40

The most common types of bacteria found as normal flora of the skin are

Back 40

gram positive cocci and rods like staphylococcus or bacillus

Front 41

When only an antigen derived from a pathogenic organisms is used as a vaccine such as the case for hepatitis B vaccine this describes what type of vaccine?

Back 41

A subunit vaccine.

Front 42

Cryptosporidium parvum oocysts are highly resistant to

Back 42

chlorine