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30 Cards in this Set
- Front
- Back
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Humoral Immunity |
Ab mediated |
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Cellular Immunity |
T cell mediated |
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Humoral immunity defends against |
Bacteria & toxins, circulating viruses |
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Cellular immunity defends against |
fungi, tissue transplants, helminthes, protozoa |
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Natural immunity |
acquired through normal life experiences |
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Active/natural immunity |
Dev. on own, ex infection |
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Passive/natural immunity |
person to person, ex. breastfeeding |
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Artificial immunity |
produced purposefully medical procedure/immunization |
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Active/artificial |
vaccines |
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passive/artificial |
immune globulin therapy |
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Antigens are ? generators |
Ab |
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Most Ag are ? |
proteins/long carb |
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Abs are ? made in response to Ag |
proteins |
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Antibody affinity |
strength with which ab binds to ag at given binding site |
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These are too small to stimulate Ab production, are coupled with another large carrier molecule (protein) |
Hatpens |
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Ex. of hapten |
penicillin |
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MHCs Class I |
specific to individual, Organ transplants found on all nucleated cells |
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MHCs Class II |
required for T cell communication, Found only on APCs |
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IF an Ag originates from cytoplasm, they are blinded to class I MHCs and presented to ____________________ |
CD8+ T Cells (endogenous) |
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If an Ag comes from outside the cell, they are binded to Class II MHCs and presented on ______________________ (T helper cells) |
CHD4+ (exogeneous) |
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The surface cell receptor for HIV |
CD4 |
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Super antigen that causes TSS |
Staphylococcal enterotoxn B |
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super antigens work by |
releasing MASSIVE amount of cytokines |
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T dependent --> produces ? |
B cells with memory |
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T independent --> ? |
Produces ab's with low affinity for ag, and NO memory B cells are formed |
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IgG |
Most common antigen in blood, can cross placenta, half life = 23 days, Y shaped |
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IgM |
Pentamer, First Ab produced during infection that agglutinates microbes, invloved in ABO blood typing |
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IgA |
Dimer, most abundant in body, breast milk, prevents attachment to Mucousal surfaces |
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IgD |
Monomer, Ag receptor on B cells |
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IgE |
Monomer, tightly bound to mast cells & basophils, elevated in response to parasite infection or allergic reaction |
