Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
|
What is the effect of activating:
Gas? Gai? Gaq? |
Gas: Stimulates adenyl cyclase to produce cAMP
Gai: Inhibits adenyl cyclase Gaq: Activates phospholipase C (PLC) |
|
|
What is the response when epinephrine binds to an alpha-adrenergic receptor?
|
-activates Gaq
-which activates PLC -which hydrolyzes PI-4,5 bisP into 2 2nd messengers -> DAG & IP3 |
|
|
What is the response when epinephrine binds to a beta-receptor?
|
-activates Gas
-which activates adenyl cyclase -which takes ATP and makes cAMP and PPi (cAMP is a 2nd messenger) |
|
|
Name the enzyme that synthesizes cAMP
|
adenyl cyclase
|
|
|
Name the enzyme that hydrolyzes cAMP
|
phosphodiesterase
|
|
|
Name the enzyme that is activated allosterically by cAMP
|
protein kinase A
|
