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31 Cards in this Set
- Front
- Back
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t(14;18) |
follicular lymphoma (BCL2 and Ig H) |
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CD10+ BCL-2+ CD19+ CD20+ |
follicular lymphoma markers |
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30% BCL-6 20% BCL-2 (14;18) 10% MYC clonal kappa or lambda |
diffuse large B cell lymphoma |
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CD15+ CD30+ CD45- CD20- EMA- |
Classical Hodgkin Markers |
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CD45+ CD20+ EMA+ D15- CD30- |
Non-lymphocyte Predominant Hodgkin makers |
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t(9;22) |
CML (BCR-ABL) ----> p210 or ALL ---> p190 |
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del(5q) |
myelodysplastic syndrome with thrombocytosis and macrocytic anemia and hypercellular marrow with megakaryocyte hyperplasia |
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CD34+ TdT+ |
ALL markers |
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t(11;18) |
20-50% of marginal zone MALT lymphoma (APl2-MLT) **lymphoepithelial lesions |
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t(11;14) |
mantle cell lymphoma (IgH and Cyclin D) |
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CD19+ CD20+ CD5+ Cyclin D+ clonal light chain |
mantle cell lymphoma markers |
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trisomy 12 |
20-30% of SLL/CLL |
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CD19+ CD20+ CD5+ CD23+ |
SLL/CLL markers |
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CD19+ CD20+ CD25+ CD11c+ CD103+ annexin |
hairy cell leukemia markers |
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BRAF V600E mutation |
hairy cell leukemia |
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BCL6+ CD19+ CD20+ CD10+ bcl2- |
Burkitt lymphoma markers |
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t(8;14) |
Burkitt lymphoma (c-myc) |
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t(2;5) |
anaplastic large T cell (ALK) hallmark cells |
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CD2+ CD5+ CD4+ CD30+ ALK+ |
anaplastic large T cell makers |
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CD3+ CD4+ CD8- |
mycosis fungoides (sezary syndrome) markers cutaneous |
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HTLV-1 and clover leaf/flower cells |
adult T cell lymphoma/leukemia |
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S-100, CD1a, langerin, Birbeck granules |
Langerhans Cell Histiocytosis |
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t(15;17) |
APL acute promyelocytic leukemia (PML-RARa) |
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t(8;21) |
RUNX1-RUNXT1 AML with neutrophilic maturation (favorable) no CD20 |
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inv(16) |
CBFb/MYH11 AML with monocyte/granulocyte differentiation and abnormal marrow esoinophils |
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t(6;9) inv(3) t(1;22) |
poor prognosis AML translocations |
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NPM1 mutation or CEBPA mutation |
AML with good prognosis unless also FLT3-ITD mutation |
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t(12;21) hyperdiploid t(9;22) t(4;11) t(1;19) hypodiploid |
ALL translocations, first 2 favorable |
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HLA-DR- CD34- |
APL makers |
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D816V mutation in KIT |
systemic mastocytosis |
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V617F mutation |
JAK2 |
