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12 Cards in this Set

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What is the fundamental morphological unit of cardiac muscle?
Sarcomere
TRUE/FALSE - The heart generates tension via the shortening of its muscular fibers, which is manifest as the ejection of a volume of blood.
False - heart generates pressue not tension
Describe the concept of Preload.
Preload is the force necessary to stretch the relaxed muscle to its initial length.
Why is Preload important?
The degree of initial stretch effects the muscle's ability to stretch upon stimulation.
TRUE/FALSE - Maximal Resting Sarcomere length is around 2.2 microns
True
Diastolic ventricular function can be thought of as chamber compliance or distensibility. What are the major determinants of compliance?
The active process of muscular relaxation and the passive elastic properties of the left ventricle which define the intrinsic stiffness of cardiac muscle are the major determinants.
Describe isotonic contractions.
An isotonic contraction is a contraction which occurs with no load on the muscle in which developed force is negligible and velocity of shortening is maximal.
Describe isometric contractions.
An isometric contraction occurs when the muscle is stimulated to contract against a load and no shortening occurs so that developed force is maximal and velocity of shortening is negligible
Afterload is determined largely by (blank) and impedance to (blank).
PVR and ventricular ejection
TRUE/FALSE - Contractility is a change in cardiac function independent of variation in AL & PL.
True
Describe the concept of Afterload.
The tension, force or stress (force per unit of cross-sectional area) acting on the fibers in the ventricular wall after the onset of shortening.
Cardiac Output = HR x ?
Stroke Volume