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8 Cards in this Set

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Magnesium Sulfate Classification
Magnesium Sulfate Mecahanism of Action
-Second most plentiful intracellular cation. Essential for the activity of many enzyme systems and plays an important role with regard to neurochemical transmission and muscular excitability
-some effects on nervous system similar to those of calcium
-Increased conc in extracellular fluid causes depression of CNS, has direct depressant effect on skeletal muscle
-Low conc in extracellular fluid results in increased acetylcholine release and increased muscle excitability that can produce tetany
Magnesium Sulfate Mecahanism of Action--SA Node and effects on blood vessels
-slows rate of SA Nodal impulse formation. Higher conc produce cardiac arrest in diastole
-causes vasodilation by direct action on blood vessels
Magnesium Sulfate Indications
-Polymorphic VT with prolonged QT interval
-Rhythm control of AFib < 48 hours duration
Magnesium Sulfate Dosing
-Torsades (pulseless): 1 to 2 g
-Torasdes (pulse)or Afib with rapid ventricular response: 1 to 2 g
Magnesium Sulfate Precautions
-caution in patients recieving digitalis
-Caution in impaired renal function
-caution with preexisting heart blocks
Magnesium Sulfate Contraindications
-Respiratory depression
Magnesium Sulfate Special Considerations
-Flushing, sweating
-bradycardia, AV block
-Respiratory depression
-Drowsiness, decreasing LOC
-diminished reflexes or muscle weakness, flaccid paralysis
-Antidote = Calcium