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13 Cards in this Set

  • Front
  • Back
3 factors that can affect urine specific gravity
1. glucose
2. protein
3. contrast media
Importance of:
1. alkaline urine pH (2)
2. acidic urine pH (1)
1. increased salicylate excretion, phosphate & calcium stones

2. cystine & uric acid stones
3 types of persistent proteinuria
1. overflow: prox tubule overwhelmed from overproduction of protein

2. tubular: tubulointerstitial damage allows smaller proteins to get through

3. glomerular: increased filtration of macromolecules
RBC urine casts are found in what 3 dss?
1. glomerulonephritis
2. ischemia
3. malignant HTN
WBC urine casts are found in what 3 dss?
1. tubulointerstitial inflam
2. acute pyelonephritis
3. transplant rejection
Granular (muddy brown) urine casts are indicative of what kidney dss?
acute tubular necrosis
Waxy urine casts are found in what type of renal ds?
chronic renal failure
4 general causes of BUN:Cr > 10:1
1. decreased perfusion

2. increased urea load

3. obstruction

4. decreased muscle mass
1. Relationship b/t plasma Cr & GFR
2. Relationship only holds in what situation?
1. inversely proportional

2. kidneys in a steady state fxn
Cockroft-Gault formula for CrCl
(140 - age) x weight
___________
72 x SCr

* x 0.85 if female
MDRD equation for estimating GFR
186 x (SCr)^-1.154 x (age)^-0.203

* x .742 if female
** x 1.21 if AA
1. What is cystatin C?
2. What happens to it in kidney?
3. Compare to serum creatinine in estimating GFR
1. protein produced by nucleated cells

2. filtered & metabolized in tubules

3. cystatin C levels do not change by diet, serum levels rise w/ smaller drop in GFR than SCr
How do you calculate fractional excretion of Na (FeNa)?
UNa x PCr
__________
PNa x UCr