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7 Cards in this Set

  • Front
  • Back
1. Primary screening test for HIV
2. Common test to confirm above positive result
3. Importance in timing of screening tests
1. ELISA for HIV-1 Abs (RULE OUT - lots of false pos, low threshold)

2. Western blot assay (RULE IN - lots of false neg, high threshold)

3. Abs may not be detectable for 1-2 mo after infection
5 possible benefits to tx of acute HIV infection
1. decrease acute dz severity

2. alter viral set point

3. reduce mutation rate

4. preserve immune fxn

5. reduce risk of transmission
5 possible risks of tx of acute HIV infection
1. drug toxicities

2. earlier drug resistance

3. limit future tx options

4. potential for indefinite tx

5. adverse effects on QOL
3 ways to dx AIDS
HIV + with:
1. CD4 < 200

2. CD4/CD8 < 1.5

3. AIDS indicator condition
Preferred regimen for PCP & Toxoplasmosis prophylaxis in AIDS pts
TMP-SMX
1. 1st choice prophylaxis for MAC in AIDS
2. When should prophylaxis be discontinued?
1. azithromycin

2. when CD4 > 100
3 ART regimens for previously untx'd HIV pts
1. 1 NNRTI + 2 NRTIs

2. 1 PI + 2 NRTIs

3. 3 NRTIs