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28 Cards in this Set

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What is the PS portion of the ANS? List components.
Craniosacral portion

CN III
CN VII
CN IX
CN X

Sacral spinal segments:
- S2
- S3
- S4
What is the sympathetic portion of the ANS? List components
Thoracolumbar portion

T1 - L2
ANS GVE innervates what three categories?
Smooth muscle
Cardiac muscle
Glands
Sympathetic outflow synapses at what type of ganglions?
Paravertebral ganglion

or

Prevertebral ganglion
Parasympathetic outflow synapses at what type of ganglions?
Intramural ganglion
What NT's are used in sympathetics?
Preganglion - ACh

Postganglion - NE
What NT's are used in parasympathetics?
Preganglion - ACh

Postganglion - ACh
The effect of NT on a target cell is determined by what?
The nature of the target cell receptors

and

Particular signal transduction mechanism that is linked
List sympathetic receptor types and describe each.
1. Alpha (EXCITATORY)

alpha 1 and alpha 2 subtypes

2. Beta (INHIBITORY)

beta 1 and beta 2 subtypes

3. Neuropeptide Y

- Vascular SM contraction
- Inhibition of NE release
- Potentiation of Epinephrine

4. ACh

Muscarinic - M1
PS stimulation of muscarinic ACh receptors does what?
PS nerve effects
Stimulation of Sympathetic alpha 1 receptors does what?
Vasoconstriction in

Viscera and Skin
Stimulation of Sympathetics beta 1 receptors does what?
Increase HR and contractability
Stimulation of Sympathetics beta 2 receptors does whta?
Dilation of bronchioles in lung
List the PS receptor types and describe each.
1. Nicotinic

Linked to skeletal muscle and cholinergic synapses in autonomic ganglia

2. Muscarinic

- M1 (EXCITATORY)
- M2 (INHIBITORY)
Describe the depolarizing physiological process associated with the nicotinic ACh receptors.
EXCITATION

Binded ACh allows

Na+ in
K+ out

from sodium/potassium channels
Describe the hyperpolarizing physiological process associated with the Muscarinic ACh receptors.
INHIBITION

ACh binds

G-protein coupled receptors influence

K+ channels to open

K+ out
Describe the depolarization physiological process associated with the Muscarinic ACh receptors.
EXCITATION

ACh binds

G-protein coupled receptors influence

K+ channels to close

K+ cannot get out
Hyperpolarization of the muscarinic ACh receptors does what?
Slower heart rate
Depolorization of the muscarinic ACh receptors does what?
Cause SM contraction in GI
Locate the preganglionic cell bodies of CN III.
Midbrain

Edinger-Westphal nu.
Locate the postganglion cell bodies of CN III.
Ciliary ganglion
Locate the preganglionic fibers of CN III
Within CN III
Locate the preganglion cell body of CN VII.
Pons

Superior Salivatory nu.
Locate the preganglionic fibers of CN VII.
Greater petrosal nerve
(to pterygopalatine ganglion)

Chorda Tympani
(to submandibular ganglion)
Locate the postganglionic cell bodies of CN VII.
Pterygopalatine ganglion

Submandibular ganglion
Locate the preganglionic cell bodies of CN IX.
Medulla

Inferior Salivatory nu.
Locate the preganglionic fibers of CN IX.
Tympanic branch of IX

Tympanic plexus

Lesser Petrosal nerve
Locate the postganglionic cell bodies of CN IX.
Otic ganglion