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18 Cards in this Set
- Front
- Back
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5' Cap
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Alternative Splicing
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process by which the exons of one pre mRNA are spliced together in different combinations, generating two or more different mature mRNAs from a single pre-mRNA
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Cleavage/ Polyadenylation Complex
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large, multiprotein complex that catalyzes the cleavage of pre mRNA at the 3' poly A site and the initial addition of adenylate A residues to form the poly A tail
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Cross-Exon Recognition Complex
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large assembly including RNA binding SR proteins and other components that helps delineate exons in the pre-mRNAs of higher eukaryotes and ensure correct RNA splicing
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Exosome
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large exonuclease-containing complex that degrades spliced out introns and improperly processed pre-mRNAs in the nucleus or mRNAs with shortened poly A tails in the cytoplasm
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FG-nucleoporins
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proteins on the inner surface of the nuclear pore complex with globular domain that forms part of the pore structure and random coil domain of hydrophilic amino acids punctuated by short repeats
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Group 1 introns
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Group 2 introns
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mRNP exporter
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a heterodimeric protein that binds to mRNA- containing ribonucleoprotein particles (mRNPs) and directs their export from the nucleus to cytoplasm by interacting transiently with nucleoporins
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Nuclear Pore Complex
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large, multiprotein structure, composed largely of nucleoporins, that extends across the nuclear envelope; ions and small molecules freely diffuse through NPCs; large proteins and ribonucleoprotein particles are selectively transported through NPCs with the aid of soluble proteins
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Poly A Tail
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pre-mRNA
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precursor messenger RNA; the primary transcript and intermediates in RNA processing
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RNA editing
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unusual type of RNA processin in which the sequence of a pre-mRNA is altered
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RNA splicing
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a process that results in removal of introns and joining of exons in pre-mRNAs
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short interfering RNAs (snRNAs)
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small nuclear RNAs (snoRNAs)
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one of several small, stable RNAs localized to the nucleus; five snRNAs are components of the spliceosome and function in splicing pre-mRNA
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spliceosome
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large ribonucleoprotein complex that assembles on a pre-mRNA and carries out RNA splicing
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SR Proteins
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