Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
|
Anesthetics with ester are degraded where?
|
Plasma
|
|
|
Anesthetics with amides are degraded where?
|
Liver
|
|
|
What local condition may prevent anesthesia
|
Acidosis limits the drugs ability to cross the lipid bilayer. Inflammation and repeat injections (a salt with HCL) may cause acidosis and limit effectiveness
|
|
|
SE of LA's
|
conduction failure, v fib like Class I antiarrhythmics
Vasodilation Excesses constriction or tachycardia if given with epi Sedation Hypersensitivity |
|
|
Injectible LA's
|
Bupivacaine
Mepivacain Lidocain Tetracaine (long) Procaine (short) |
|
|
For Ophthalmology
|
Tetracaine
|
|
|
Low water solubility so good for ulcerated surface and open wounds
|
Benzocaine
|
|
|
Procaine
|
ester
low potency slow onset short course of action |
|
|
the first LA
|
Procaine
|
|
|
Lidocaine
|
amide
more potent than procaine rapid onset and long action |
|
|
Mepivacaine
|
amide
longer duration than lidocaine no need for epi so good for elderly or those with cardio diseas |
|
|
Bupivacaine
|
amide
much more potent than procaine good for epidural anesthesia |
|
|
Good continuous epidural anesthesia
|
Bupivacaine
|
|
|
Does not require epinepherine so ideal for elderly or those with cardiovascular disease
|
Mepivacaine
|
|
|
Tetracaine
|
ester
much more potent than prcaine slow onset long duration |
|
|
Benzocaine
|
Active topically only
|
