Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
14 Cards in this Set
- Front
- Back
|
what is the purpose of ritonavar? what is the suffix of a protease inhibitor? NS5A replication complex inhibitor? NS5B polymerase inhibitor? |
not active, just increase levels of other HCV meds previr asvir buvir |
|
|
What are the generic components of epclusa? what is it approved for? what is a major drug interaction with Harvoni and epclusa? what does it cause? |
sofosbuvir, ledipasvir, velpatasvir all HCV genotypes amiodarone bradycardia |
|
|
what is the boxed warning for all direct acting antivarials (drugs with suffix described previously? what are the generic components of viekira pak? what are the colors and dosing of the tablets? major drug interactions with what? what specific drugs are contraindicated? |
reactivation of HBV paritaprevir, ritonavir, ombitasvir and seperate dasabuvir triple drug one is pink and given QD dasvbuvir is beige and given BID 3a4 inducers and 2c8 (dasabuvir) inducers and inhibitors lovastatin, simvastatin, ethinyl estridiol |
|
|
what are the generic components of zepatier? what drug are the contraindications? |
elbasvir and grazoprevir strong 3a4 inducers or OATP1b1 inhibitors |
|
|
what are all direct acting antivirals contraindicated in? Other than cyp stuff, what is a major drug interaction with harvoni and epclusa? |
strong 3a4 inducers H2RAs and PPI decrease concentrations |
|
|
what is the brand name for inhaled ribavirin? what is a boxed warning for ribavirin? Can you get pregnant while on this drug? |
Virazole, used for respiratory syncytial virus hemolytic anemia if G6PD deficiency no it is a teratogen, two modes of contraception, and avoid pregnancy 6 months after discontinuing |
|
|
what has liver disease is interferon used to treat? boxed warnings for interon? what are the major side effects of interferon? |
HBV and HCV neuropsychiatric, autoimmune disease, infections myelosuppression, flu like syndrome, CNS effects |
|
|
what are the nucleoside/tide reverse transcriptase inhibitors used to treat? when do all NRTIs get dose adjusted? what is a boxed warning for all NRTIs? |
HBV and HIV, need to test for HIV to prevent resistance crcl below 50 lactic acidosis and hepatomegaly with steatosis |
|
|
generic of viread? generic of vemlidy? major side effects of tenofovir? major side effect of adefovir? |
tenofovir disoproxil furmarate tenofovir alafenamide renal tox, osteomalacia, decrease bone mineral density, fanconi syndrome renal impariment/tox |
|
|
major side effect of telbivudine? what drugs have boxed warning for liver damage? when should a hepatotoxic drug be d/ced? |
CPK acetaminophen, isoniazid, nevirapine, NRTIs, tipranavir, valproic acid if LFTS are 3 times UNL |
|
|
what drugs are use to prevent alcoholic relapse? what is the benefit of using octreotide in liver disease? brand name for octreotide? |
naltrexone, acamprosate, disulfram it is a selective splanchnic vessel constrictor sandostatin |
|
|
brand for nadolol? brand for propranolol? what are some side effects of lactulose? what antibiotics are used to treat hepatic encephalopathy? |
corgard inderal flatulence, diarrhea rifaximin and neomycin and metronidazole |
|
|
brand name for rifaxmin? major side effect of neomycin? major side effect of metronidazole? |
Xifaxan neurotox and nephrotox peripheral neuropathies |
|
|
what is the typical drug therapy for ascites? what are the treatments for hepatorenal syndrome? |
spirnolactone alone or in combination with furosemide, furosemide is never used alone albumin, octreotide, and midodrine (alpha 1 agonist) all to improve perfusion of the kidney |
