Lisa Heme -1- 13

Front 1

Microctyic anemia
Normal FE and TIBC, and FEP
Hi Retic count;

Back 1

Thalassemia
HPSM, target cells ~ w/ what

Hint 1

beta thal

Front 2

Microctyic anemia
Normal FE and TIBC
Hi FEP, retic count nl or low;
HA, lethargy, constipation

Back 2

Lead Poisining;
what's on x-ray;
what level is of concern and what do you do?

Hint 2

lead lines;
> 10, ? recheck - find out
Lead > 10: level of concern; 20-24: determine source of lead, evaluate Fe status; 25-44: remove lead source: chelate

Front 3

Microcytic anemia
Low serum FE, Hi TIBC

Back 3

Iron Defeiciency
- Diet, blood loss, menses, ulcer, varices, GI, malabsorption, pregnancy

Front 4

Rare AD
ANC < 3000 (nl range 3,000-5000)
Q 21 days, fever, x 1 week, then rises again
stomatitis, oral/GI uclers, skin infx, PNA, sepsis

Back 4

congenital Neutropenia

Front 5

Loss of genes:
1 --> ?
2-
3-
4-

Back 5

Hgb H: Loss of genes:
1 → SILENT carrier, ‘
2→ mild alpha thal
3→ Hemoglobin H
4→ Hemoglobin Barts/incompatible w/ life

Front 6

< 4 yo, > URI/AGE; what bug ~ with
- pale,; HGB 5-9; anemic
-HPSM, vomiting, abd pain,
bloody diarrhea; dehydration

Back 6

~ E.coli 0157:H7 (meat/pools); HUS
-Labs: Low plt (vs HSP!!!- nl PLT) , Hi WBC, Nl clotting studies;
-BURR/Helmet cells
-what's treatment

Hint 6

fluid/lytes/avoid anbtx

Front 7

define ANC

Back 7

WBC x % Neutrophils: Nl range: 3,000-5,000;
# < 3,000 = neutropenia

Front 8

Physiol drop in HCt by month 2-3 (8-10 wks) ; even in premie
-what's cause? and treatment

Back 8

Anemia of NB: Low EPO production
no tx unless cardiovascular compromise

Front 9

Hi Ferritin; but Low Fe;
Microcytic anemia or Nl MCV
Low TIBC, hi ferritin

Back 9

Chronic illness: plenty of stored ron but not getting to BM

Front 10

> 6 mo, BF infants; or cow’s milk;
Low Fe ; low hgb (<6) ; HI FEP
Low ferritin, Hi TIBC

Back 10

Iron def anemia,
what's common cause and peak?

Hint 10

> 6 mo, BF infants; or cow’s milk;
Tx: Fe, cont until ferritin Nl (< 12 mo)
pk: 6mo -3 y

Front 11

hair on end”, HPSM, thick bones;
-deficiency of beta globin due to mutation in both beta globin gene

Back 11

Major: “beta Thal;
what's complx and tx

Hint 11

Tx: chronic transfusion;
Complx: cholelithiasis, hemosiderosis (iron dep in heart, liver, pancreas)

Front 12

Hi Hgb F, and S

Back 12

Sickle cell anemia

Front 13

What will decrease Fe absorption in small intestine

Back 13

Oxylates

Front 14

What’s best parameter to determine adequacy of Fe replacement therapy

Back 14

increase in ferritin

Front 15

what's nuclear remnan that, suggest functionoal asplenia, extra medullary hematopeoiesis or marrow replacement by malignancy

Back 15

Howell Jolly bodies:

Front 16

what are Heinz bodies and what's associated w/ it?

Back 16

aggregated Hgb ~ thalassemia, G6PD def

Front 17

Basophilic stippling? and ~

Back 17

aggregated ribosome’s ~ thallesemia, unstable HB, iron deficiency (lead poisoining

Front 18

what are Schistocytes and ~ with?

Back 18

fragmented cells/fibrin strands: microangiopathic hemolytic anemia (HUS/TTP, DIC)

Front 19

Macrocytic anemia w/ megaloblastic changes ~ with what?

Back 19

nuclear dysmaturity, hyperseg polys due to B12/folate deficiency

Front 20

What's cause of Macrocytic anemia w/o magalobalstic changes and ~ ?

Back 20

bone marrow failure syndromes: DBA, Fanconi’s, aplastic anemia, preleukemia-myelodysplastic; drugs, chronic liver diz, hypothyroidism

Front 21

What are Giant platelets and ~ ?

Back 21

reticulocytes, seen in peripheral destruction w/ subsequent marrow compensation

Front 22

PE: Hypotrophic thenar eminence, Absent thumbs
short
~ syndrome

Back 22

Fanconi’s

Front 23

Angular stomatitis

Back 23

Iron deficiency

Front 24

Triphalangeal thumbs, short

Back 24

DBA (thumb looks like 5th finger)

Front 25

Hyperpigmentation

Back 25

Fanconi’s

Front 26

Anemia @ 3-6 mo suggests ?

Back 26

hemoglobinapthy or thalessemia syndrome

Front 27

Hb F ~ which globin chains

Back 27

alpha2, gamma2

Front 28

what to watch out for for patients w/ chronic blood transfusions

Back 28

Iron overload, need to start chelation therapy to remove excess iron or will get hemosiderosis (buildup in liver) and hearts

Front 29

Alpha2, beta 2

Back 29

Hgb A, ? human

Hint 29

Normal adult Hb

Front 30

Alpha2 delta 2

Back 30

A2

Hint 30

Hi in Beta Thal

Front 31

Alpha2 gamma2

Back 31

F

Hint 31

Major Hb in Fetal life

Front 32

Beta 4

Back 32

H

Hint 32

ALPHA thal, unstable, non-functional

Front 33

Gamma4

Back 33

Bart’s

Hint 33

Alpha Thal – NB period, unstable, nonfxnal

Front 34

O2 Dissociate curve LEFT shifting causes?

Back 34

Hb F, fetal life, alkalosis, low 2,3 DPG

Front 35

O2 Dissociate curve RIGHT shifting causes?

Back 35

Acidosis (Bohr effect), hypoxia: HI 2,3 DPG, sepsis, hi altitude,

Front 36

? anemia Hi ferritin, Low Fe, Low TIBC

Back 36

Chronic Illness

Front 37

? anemia has Low ferritin, High TIBC

Back 37

Iron Deficiency