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15 Cards in this Set
- Front
- Back
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What breaks down dietary triglycerides to free fatty acids and monoacylglycerol?
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Pancreatic Lipase
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What converts chylomicron triglycerides to free fatty acids and glycerol?
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Lipoprotein lipase
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What lipolyzes adipose triglycerides into free fatty acids and glycerol?
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Adipose lipase
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What happens to the products of the pancreatic lipase?
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they cross the mucosal cell membranse and are then used to synthesizechrylomicron (a lipoprotein) triglycerides
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What happens to the free fatty acids and glycerol produced by lipoprotein lipase?
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The free fatty acids cross the adipocyte cell membranes into adipose cells. The adipocytes use these fatty acides (with a new glycerol-3P derived from adipose glycolysis) to synthesize adipocyte triglycerdies
The glycerol goes to the liver |
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What happens to the free fatty acids and glycerol produced by the adipose lipase?
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the free fatty acids leave the adipocytes and are bound to albumin for transport to the bloodstream, enter beta oxidizing cells, cross into these cells mitrochondria and are catabolized there
The glycerol goes to the liver |
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Where does the glycerol go from the triglyceride lipolysis (fed or fasted)?
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The liver
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Why does all the glycerol go to the liver from triglyceride lipolysis?
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This assures that glycerol from triglyceride breakdown is recycled into triglycerdides only if it is not needed by the liver
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Where is the glycerol rephosporylated to glycerol-3-phosphate?
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Only in the liver
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Why can the glycerol only be rephosphorylated to glycerol-3-phosphate in the liver?
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Because only the liver has glycerol kinase to catalyze the process
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What does glycerol kinase do in the fed state?
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Catabolize glycerol-3-p for energy via glycolysis, or it can be rephosphorylated and used for hepatic triglyceride synthesis
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What happens in the fasted state to glycerol-3-P?
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all of it is converted to glucose via gluconeogenesis
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What controls the pancreatic lipase?
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the amount of triglyceride ingested
food ingestion leads to pancreatic secreation of digestic enzymes |
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What activates the lipoprotein?
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insulin
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What activates adipose lipase?
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via a phosphorylation process, by glucagon and epinephrine
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