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25 Cards in this Set

  • Front
  • Back
what are the 6 components of the limbic system?
1. hippocampal formation
2. mamillary bodies
3. ant thalamic nuclei
4. cingulate gyrus
5. amygdaloid nucleus
6. septal nuclei
what are the 3 functions of the limbic system?
1. coordinates activity of the hypothalamus
2. it is the substrate for strong emotional experience and expression
3. forms long term declarative memories (hippocampal formation)
sham rage
-rage behavior without any stimulus
what brain areas modulate rage behavior?
-hypothalamus is critical for expression of rage
-this behavior is modulated (dec) by cortical activity
what does general stimulation of the cingulate gyrus do?
-dec breathing rate, HR, and BP
-alters peristalsis and dilates pupils
what does stimulation of ant cingulate gyrus do?
-produces agressive behavior
what is the amygdala a link between?
-cortical structures that process sensory info and hypothalamic and BST effector systems
what does the centromedial nuc project to?
-visceral nuclei of the BST
what is the centromedial nuc concerned with?
-autonomic functions
-stimulation produces salivation, licking, and chewing
what does the basolateral nuc connect with?
-thalamus and cerebral ctx
where do the major efferents from the basolateral nucleus project?
-to the hypothalamus via the stria terminalis
what is the basolateral nucleus associated with?
-arousal and inc attention
-strong stimulation produces rage and fear behavior
what subnucleus may be involved with learned behaviors related to fear?
-the basolateral
what are the three structures that comprise the hippocampal formation?
-the subiculum
-dentate gyrus
what type of ctx are the hippocampus and dentate gyrus?
what type of neurons are in the dentate gyrus and where do they project?
-granule cells
-project to pyramidal neurons in the hippocampus
what symptom is common in patients that have damage to hippocampal structures?
-anterograde amnesia (cant form new, long term declarative memories)
what is the major input to the hippocampal formation?
-glutaminergic innervation from the entorhinal ctx
what are the three major outputs of the hippocampal formation?
-entorhinal ctx
-cingulate gyrus
what are the 2 bundles of the fornix?
-precommissural: pyramidal axons from hippo proper to septal nuclei
-postcommissural: axons from subiculum to mamillary bodies
what are the three major connections of the septal nuclei?
-dentate gyrus
what do septal nuclei lesions produce?
-transient rage
-inc drinking
what does spetal nuclei stimulation produce?
-pleasure rewarding effects
-slows HR
what is kluver bucy syndrome and what are some of its presentations?
-damage to anterior/medial temporal lobes
amnestic confabulatory syndrome
-bilateral infarction of the hippocampal formation
-anterograde amnesia