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25 Cards in this Set
- Front
- Back
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what are the 6 components of the limbic system?
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1. hippocampal formation
2. mamillary bodies 3. ant thalamic nuclei 4. cingulate gyrus 5. amygdaloid nucleus 6. septal nuclei |
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what are the 3 functions of the limbic system?
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1. coordinates activity of the hypothalamus
2. it is the substrate for strong emotional experience and expression 3. forms long term declarative memories (hippocampal formation) |
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sham rage
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-rage behavior without any stimulus
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what brain areas modulate rage behavior?
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-hypothalamus is critical for expression of rage
-this behavior is modulated (dec) by cortical activity |
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what does general stimulation of the cingulate gyrus do?
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-dec breathing rate, HR, and BP
-alters peristalsis and dilates pupils |
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what does stimulation of ant cingulate gyrus do?
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-produces agressive behavior
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what is the amygdala a link between?
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-cortical structures that process sensory info and hypothalamic and BST effector systems
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what does the centromedial nuc project to?
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-visceral nuclei of the BST
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what is the centromedial nuc concerned with?
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-autonomic functions
-stimulation produces salivation, licking, and chewing |
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what does the basolateral nuc connect with?
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-thalamus and cerebral ctx
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where do the major efferents from the basolateral nucleus project?
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-to the hypothalamus via the stria terminalis
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what is the basolateral nucleus associated with?
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-arousal and inc attention
-strong stimulation produces rage and fear behavior |
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what subnucleus may be involved with learned behaviors related to fear?
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-the basolateral
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what are the three structures that comprise the hippocampal formation?
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-the subiculum
-hippocampus -dentate gyrus |
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what type of ctx are the hippocampus and dentate gyrus?
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-allocortex
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what type of neurons are in the dentate gyrus and where do they project?
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-granule cells
-project to pyramidal neurons in the hippocampus |
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what symptom is common in patients that have damage to hippocampal structures?
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-anterograde amnesia (cant form new, long term declarative memories)
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what is the major input to the hippocampal formation?
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-glutaminergic innervation from the entorhinal ctx
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what are the three major outputs of the hippocampal formation?
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-entorhinal ctx
-cingulate gyrus -fornix |
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what are the 2 bundles of the fornix?
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-precommissural: pyramidal axons from hippo proper to septal nuclei
-postcommissural: axons from subiculum to mamillary bodies |
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what are the three major connections of the septal nuclei?
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-hippo
-fornix -dentate gyrus |
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what do septal nuclei lesions produce?
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-transient rage
-hyperemotionality -hyperactivity -inc drinking |
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what does spetal nuclei stimulation produce?
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-pleasure rewarding effects
-slows HR |
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what is kluver bucy syndrome and what are some of its presentations?
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-damage to anterior/medial temporal lobes
-hyperphagia -hypersexuality -docility |
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amnestic confabulatory syndrome
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-bilateral infarction of the hippocampal formation
-anterograde amnesia |
