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40 Cards in this Set
- Front
- Back
NL WBC IS
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5,000-10,000
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TWBC INCLUDES
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GRANULOCYTES,, LYMPHOCYTES, & MONOCYTES
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60% OF ALL WBC'S ARE
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GRANULOCYTES
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93% OF ALL GRANULOCYTES ARE
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NEUTROPHILS
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CERTAIN DRUGS, DRUG TOXICITY,, DRUG HYPERSENSIVITY OR SOME, DISEASES
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CAUSES of neutropia
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MOST COMMON , CAUSE, IS
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IATROGENIC
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TWO TYPES OF DRUGS SUPPRESS GRANULOCYTE, PRODUCTION
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CANCER CHEMOTHERAPEUTIC DRUGS (ALWAYS), IMMUINOSUPPRESSIVE DRUGS
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LEUKEMIA, HIV, BONE, MARROW TUMORS
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DISEASES THAT SUPPRESS GRANULOCYTE PRODUCTION
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The faster the drop and the longer the duration of neutropenia
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the more danger that the patient will develop an infection
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1ST 2-3 DAYS PATIENT C/O
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FATIGUE, WEAKNESS, NON-\PRODUCTIVE COUGH, SORE THROAT
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neutropenia SYMPTOMS 1ST 2-3 DAYS MAY SEEM LIKE
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MINOR COMPLAINTS BUT CAN PROGRESS
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LATER PT. DEVELOPS ADDITIONAL SYMPTOMS
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FEVER, CHILLS, SEPSIS & SEPTIC SHOCK (IF UNTREATED)
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SYMPTOMS USUALLY NOT PRESENT WITH NEUTROPENIA
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CLASSIC SIGNS OF INFECTION , PURULENT DRAINAGE, REDNESS, SWELLNG
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CLASSIC SIGNS OF INFECTION ARE USUALLY NOT PRESENT, (PURULENT DRAINAGE, REDNESS, SWELLNG), D/T DIMINSHED
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PHAGOCYTIC RESPONSE
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CLASSIC SIGNS OF INFECTION ARE USUALLY NOT PRESENT, WBCS ARE MAJOR COMPONENT OF
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PUS
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SYMPTOMS WITH neutropenia THE TEMP (FEVER)
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MAY NOT BE OVER 100
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A TEMP. OF IS CONSIDERED TO BE AN INFECTION UNTIL, PROVEN OTHERWISE WITH NEUTROPENIC PT
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ANY
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What is the etiology of netrupenia?
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normal flora
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What is the treatment if a fever develops with a neutropenic pt?
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immediate antibiotics (within one hour)
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How are antibiotics used to treat neutropenic pt?
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combination
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Why are antibiotics used in combination with neutropenic pt?
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syngergistic effect
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What type of medication is used with antibitoic to treat neutropenic pt?
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aminoglycosides
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Give 2 examples of antibiotics used to treat neutropenic pts?
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cephalosporin & pnenicilliln
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What type of infusion may be given to treat neutropenic pt?
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granulocyte transfusion
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Give 2 examples of granlocyte conlong-stimulating factr (GCSF or GM-, CSF) that might be used to treat pt with neutropenia?
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neupogen, filgatrin
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What's the mortality rate of pts w/neutropenia that aren't , treated?
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80% die in one week
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What is a new prevention protocol with chemo pts to reduce , chance of getting neutropenic?
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give filgastrin 24 hrs after chemo
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Leukopenia is diagnosed when TWBC is ?
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<4000
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Leukopenia is diagnosed when neutrophil count is?
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500-1000
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Pt is at moderate risk with a TWBC of?
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4000
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Pt is at moderate risk with a neutrophil count of?
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500-1000
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Pt is at severe risk with a neturophil count of?
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<500
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Bone marrow characteristic found with leukpenia, when doing , diagnostic bone marrow aspiration?
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absence of granulocytes
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urine, muoth & throat cultures are postive for 2 things in pt. with , leukpoenia (neutropina/agranulocytosis)?
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postive for either bacteria or overgrowth of normal flora
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How are blood cultures done with leukopenic pt, for diagnostic , purposes
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serial blood clutures
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What s/b monitored when giving meds to neutropenic pt?
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WBC
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What should nurse being observing for with neutropenic pt
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fatigue
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Should the nurse encourage fluids in pts with neutropenia?
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yes - force fluids
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Giving GM-CSF is used in management of what type of pts?
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neutropenic
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Laminar air-flow & hepa air filters a re used in the management of , what type of pts?
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neutropenic
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