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18 Cards in this Set

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Leukocytes develope from ________________ in the_________
Pluripotent stem cell
bone marrow
Sequence of maturation of granulocytes
Myleblast
Promyelocyte
Myelocyte
Metamyelocyte
Band Neutrophil
Segmented neutrophil
Phagocytic system
Neutrophils
Eosinophils - parasites
Macrophages (tissue only)
Less specific phagocytosis
Sequence of maturation of Agranulocytes
Lymphocytes:
Lymphoblast
Proplymphocytes
Lymphocytes
Monocytes:
Monoblast
Promonocyte
Monocyte
Physiologic Leukocytosis
Young, excited fearful animals
Mild neutrophilia wo left shift
Mild lymphocytosis
uncommon in k9, common in cats and horses
caused by stress
Stress Leukocytosis
corticosteroid therapy
stress, pain, extreme change in temp.
neutrophilia wo left shift
lymphocytopenia
eosinopenia
+-monocytosis
more common in cats than dogs
Inflammatory Leukocytosis
infections
neutrophilia w/ left shift
bacterial, protzoal, fungal and viral infections
degree of neutrophilia; localized pus has greater response than pyo
Non-Inflammatory leukocytosis
Physiologic leukocytosis
stress leukocytosis
Neutrophilia
inflammation
stress/corticosteroids
excitement
leukemia
bacterial infection
Neutropenia
severe bacterial infection
viral infections
panleukopenia
K9 parvo
K9 hep
immunosuppresants
neoplasia
Lymphocytosis
excitement
leukemia
lymphosarcoma
post vaccination
viral/bacterial infection
Lymphocytopenia
stress/corticosteroids
acute systemic disease
immuno deficiency
Monocytosis
chronic inflammation
stress/corticosteroids
Eosinophilia
intestinal parasites
HW
hypersensitivity
Eosinopenia
stress/corticosteroids
Basophilia
HW
allergic respiratory disorders
OCCURS with Eosinophilia
Neutrophils
Phagocytic - engulf and destroy bacteria and other particles
survives up to 10 hrs in blood;1 day in tissues
cells more immature than myleocytes are unable to engulf partical matter
Lymphocytes - 2 types
gut-associated - plasma cells
produce antibodies
thymic-associated - cellular immunity responsible for graft rejection and hypersenstivity reaction