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20 Cards in this Set

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What does staining with MPO indicate?
Granulocytes
What does staining with NSE indicate?
Monocytes
What does staining with PAS indicate?
Erythrocytes and lymphocytes
Leukemia:
t(15;17)
Promyelocytic
PML-RAR - treat with ATRA
Leukemia t(8;21)
Myeloblastic w/maturation
Leukemia:
inv(16)
Myelomonocytic
Also gum involvement
Markers for B cell ALL
CD19, CD20, CD10 (CALLA), HLADR-
Markers for T cell ALL
CD2, CD3, CD7
(CD2 is also seen in APML)
What translocations are commonly seen in B-ALL?
t(8;14)
t(1;19)
t(9;22) - worse prognosis
t(8;22)
t(2;8)
t(4;11) - bad - also biphenotypic AML
t(17;19)
What translocations are commonly seen in T-ALL?
t(11;14), t(1;14), t(10;14)
Lymphoma:
Trisomy 12
Del 13q14
Del 11q22-23
SLL/CLL
Lymphoma:
CD19, 20, 5, 23+
SLL/CLL
Lymphoma
t(11;14)
Mantle Cell Lymphoma (worst prognosis)
Lymphoma
CD23-
MCL
Lymphoma
t(14;18)
Follicular Lymphoma
Back to back follicular growth, no white spaces, centroblasts and centrocytes
Follicular Lymphoma
t(14;18)
Lymphoma
t(11;18), Trisomy 3
Marginal Zone Lymphoma (MALToma)
Does not respond to abx when there is this abnormality)
Lymphoma
t(8;14)
Burkitt's
Starry sky appearance
Associated with EBV, jaw lesion
Lymphoma:
Loss of CD2, 3, 5, 7
Peripheral T cell lymphoma
Lymphoma:
t(2;5)
Anaplastic Large Cell Lymphoma
Stains for ALK protein