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20 Cards in this Set
- Front
- Back
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the most common symptom of _____is pain
a. soft tissue sarcoma b. ALL c. Bone tumors d. AML |
bone tumors
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the most common occurign soft tissue sarcoma is
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malignant fibrous histocytoma
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The type of leukemia which represents 80% of all childhood leukemia cases and 20% of adult leukemias is
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ALL
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bone tumors occur most commonly in what age group
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adolescence
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teh most common leukemia occuring in the western hemisphere and primarily occuring in the elderly >70 years
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CLL
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___is the most common site of occurance of soft tissue sarcomas
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lower extremity
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the tx plan often includes use of Bulsufan, hydroxyurea, interferon, and allogeneic bone marrown transplants which is the only curative therapy and radiation therapy reserved for palliation
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CML
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each of the following are correct statements concerning bone tumor except
a. in children often occurs in areas of rapid growth especially in the distal femur and proximal tibia b. most common malignant lesion in bone are osteosarcoma c. second most common primary bone tumore is chondrosarcoma d. most common malignant lesion is in the bone is metastatic |
"most common malignant lesion in bone are osteosarcoma"
FALSE B/C MOST COMMON BONE LESION IS METS! |
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___is the only leukemia not associated with radiation
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CLL
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rdiation therapy may play a role in teh tx of which of the following bone tumors
a. chondrosarcoma b. osteosarcoma low grade c. soliatary plasmacytoa d. high grade osteosarcoma |
solitary plasmacytoma
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sequence the common tx process used to tx ALL in peds
1. CNS tx 2. Consilidation and maintance 3. Remission induction 4. Intensification |
3,4,1,2
remission induction, intensification, CNS tx, Consilidation and maintance |
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Which of the following are correct regrading tx of soft tissue sarcoma?
1. standard of care is to tx w/combined surgery and RT approach w or w/o chemo 2. high grade tumors may be tx'd w/ preoperative dose of 45-50Gy to fild w/5cm margin on the tumor mass 3. bolus skin or superficial tissue involved 4. common beam energy is 15-18MV 5. High grade tumors may be tx'd with a post-op dose of 64.8-70.2 Gy using shrinking field techniquue w/10cm margin around surgical scar to initial volume to 40-50Gy then CD w/5cm magin to 55.8-59.4 then second CD to 64.8-70.2 w/2cm margin 6. leave at least 1cm strip of skin untreated if treating an extremity tumor to reduce lymphedema |
1,3,5,and 6 are correct
for 2: margin should be 8-10cm |
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a block in differentiation of hematopoietic or lymphopoietic cells leading to accumulation of immature blasts forms in the blood, BM, and extramedullary sites are associated with
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ACUTE leukemia
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previous radiation exposure has been linked with each of the lfollowing bone cancers EXCEPT
a. fibrosarcomas b. osteogenic sarcomas c. ewings sarcoma d. chondrosarcomas |
all linked to previous RT exposure except ewings sarcomas
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Splenic irradiation has been used to reduce lymphocyte load in patients with CLL, decrease spleen size and pain with doses of :
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.25-1Gy/fx to total dose1-12Gy
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which of the following tumors are derived from mesenchymal tissue
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soft tissue sarcoma
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sarcomas tend to spread most commonly through
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blood
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complications/side effect of pneumonitis and pulmonary fibrosis is associated with
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Bleomycin
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doses of 50-70Gy with prolonged fractionated tx schedules are often required when txing each of the following bone tumors EXCEPT:
a. ewings sarcoma b. solitary plasmacytoma c. metastatic carcinoma d. fibromascomas |
metastatic carcinomas
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the role of RT in the tx of leukemia has been used for each of teh following EXCEPT
a. TBI for BMTs b spleen often leads to absocopal effect in circulating blod elements c. primary modality since it is a radiosensitive tumor d. whole brain irradiation and or testicular irradiation to tx leukemic infiltrates into sanctuary sites |
all correct except " primary modality since it is a radiosensitive tumor"
leukemias are blood cancers therefore it would be CHEMO |
