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35 Cards in this Set
- Front
- Back
Most estrogen patches apply twice weekly. What are the exceptions?
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1) Estradiol TS (generic, Mylan)
2) Climara (once a week) 3) Climera Pro (once a week) |
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What is the MOA of Plavix?
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ADP inhibitor
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What class of...
- Argatroban (adjust for liver) - Lepirudin (Refludan)-> adj. for renal function - Bivalirudin (Angiomax)--> adjust for renal function |
Direct thrombin inhibitors (DTI)
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What class of
- Abciximab (Repro) - Eptifibitide (Integrilin) - Tirofiban (Aggrastat) |
Glycoprotein IIb/IIIa
(Must be give with heparin and aspirin) |
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What class of
- Streptokinase (STK) - Anistreplase (APSAC) - Urokinase (Abbokinase) - Alteplase (Activase) - Reteplase (Activase) - Tenecteplase (TNKase) |
Thrombolytics and Fibrinolytics
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Meperidine (Demerol)has XXX effect (maybe useful in patients with bradycardia).
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XXXX --> anti-cholinergics
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What are the 5 major risk factors for CHD?
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1. Cigarette smoking
2. HTN, or on Anti-HTN meds 3. Low HDL 4. Family history 5. Age (m>45, f>55) |
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Which HMG CoA reductase inhibitor needs take with FOOD and take at PM?
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Lovastatin (Love FOOD at night) Mevacor
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Which HMG CoA reductase inhibitors need to take at PM?
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1) Lovastatin
2) Fluvastatin 3) Simvastatin |
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What are the 2 statins no renal adjustment?
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1. Lipitor
2. Fluvastatin (Lescol) 2C9 inhibitors |
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What are the CI in using combined OC pills?
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1. age > 35 and smoking
2. DVT 3. Breastfeeding 4. Breast cancer |
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What are estrogen pharmacology?
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1. Endometrial proliferation
2. Inhibits ovulation by suppressing release of FSH and LH 3. Accelerate ovum transport, decreased fertilation |
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What are progestin pharmacology?
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1. Suppress ovulation by decreased LH
2. Thicken cervical mucus 3. Endometrial transformation |
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What is the unique about Triphasil (EE/P) combination?
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EE: 30/40/30 mcg
Levo: 0.05/0.075/0.125 mg Both (EE/Levo) change three times |
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What 3 oral birth control pills can be used for acne?
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1. Ortho-Tricyclen
2. Estrostep Fe 3. Yasmin |
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What is the unique formulation about Mircette?
EE/desogestrel (20 mcg/0.15 mg) for 21 days, placebo x 2 days; and EE 10 mcg for 5 days |
Used for menstrual migraines, mood swings associated with estrogen withdrawal
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What is the monitoring parameter Yasmin and Yaz?
Yasmin EE (30 mcg) for 21 days Yaz EE (20 mcg) for 24 days |
K+ level (drospirentone blocks aldosterone receptors--> increased Na/H2O excretion --> Increased K+ retention
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Seasonale vs. Seasonique
(EE 30 mcg/ levo 0.15 mg for 84 days) |
No placebo in Seassonique
(7 days in Seasonale) |
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What are indications for MINI-pills? (progestin only)
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1. smokers
2. Breastfeeding 3. people who are CI to estrogen and migraine sufferers |
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List few examples of Mini-pills (Norethindrone 0.35 mg)
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1. Camila
2. Errin 3. Micronor - No placebo pills - Must take at the same time every day |
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Ortho Evra Patch
(more estrogen exposure than oral OCP) |
Apply once a week for 3 weeks
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Nuva-ring
(Fertility returns 19 days after ring is removed.) |
1 ring for 3 weeks
(no Sunday starts. Day 1 to day 5 during menstrual cycle) |
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Depo Provera can be given IM or SQ. Give Q3 months.
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IM: 150 mg Medroxyprogesterone acetate
SQ: 104 mg |
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Mirena (Intrauterine device)
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last for 5 years
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Implanon (implants birth cnotrol device)
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for 3 years
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Too much estrogen in birth control pills.
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1. Bloating
2. INcreased BP 3. Breast tenderness |
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Too much progestin in birth control pills.
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1. Fatigue
2. Change mood |
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Adverse efects of Thiazide diuretics.
1. Hypovolemia 2. electrolytes a) b) 3. Metabolic: increased c) d) e) 4) dermatologic: rash and photosensitivity |
a) Hypo: K, Na, Mg, Cl
b) Hyper: Ca c) Blood glucose d) Lipid e) Uric acid |
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Thazide diuretics should use cautionsly in...
A) B) C) |
A. Diabetes
B. Gout C. CrCl< 30 ml/min (except for Metalozone and Indapamide) |
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ACE inhibitors inhibit Bradykinin breakdown. What the side effects from ACEi are due to Bradykinin?
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1. Cough
2. Angioedema 3. Rash 4. Loss of taste |
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ARBs: Angiotensin receptor Blockers.
MOA: A Dosage: B |
A. Block AT1 receptors
B. QD dosing |
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Verapamil and Diltiazem are sustrators and inhibitors of ????.
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P450 3A4
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List 3 BB drugs can be used in HTN urgency.
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1. Captopril
2. Clonidine 3. Labetolol |
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What is Anti-HTN DOC for pregnant women?
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Methyldopa
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Tekturna (Aliskiren)
A. MOA: B. Adverse effects: C. Take before or after meals (Fatty meals decreased absorption) |
A. MOA: direct renin inhibitor
B: Diarrhea |