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13 Cards in this Set

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heteroxenous life cycle
life cycle in more than 1 host-invert/vert
What are the stages in the life cycle of a leishmania?
1. Amastigote-when in vertebrate tissues
2. Promastigote-when in gut of fly
infected
internal

ex. trypanosome
infested
external

ex. fly larvae
suprapylaria
midgut before moving anterior
peripylaria
develop in hindgut
L. Tropica
L. Major
tropical diseases that cause oriental sores.

cutaneous leishmaniasis
lesion
abnormal pathology
L. donovani
causes Kala-Azar or Dum Dum Fever, distributed in Africa and India

Pathogenisis and Chronic Disease
pathogenesis
onset of causing disease
What is the life cycle of L. donovani?
The infected fly bites the human, parasites are engulfed by macrophages (out of vascular) which are killed by parasite. The cycle continues where macrophages burst and infect others till the reticuloendothelial (moncyte & macrophage) system is severly damaged. Human suffers annemia and death
Dermal leishmanoid
develops in 5-10% of infected humans in India. It causes disfiguring
L. Braziliensis
S. America, causes the disease called espundia (mucocutaneous leishmaniasis)

causes ulcers