Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
recognition
|
B cell receptors bind to antigen, take in and digest antigen, then display epitopes on its MHC-II protein
-After costimulation by Th cell, divide repeatedly, differentiate into plasma cells, produce antibodies specific to that antigens atibodies |
|
Attack
|
antibodies bind to antigen, render it harmless, "tag it" for destruction
|
|
antigens bind
|
t specific complementary receptors
|
|
Th cells bind
|
to antigen presented on surface of B-Cell and releases interlukens
|
|
plasma cells full of
|
rough ER
|
|
Humoral Immunity Process
|
present > check >D.check >clone >turn into plasma or memory cells
|
|
difference between humoral and cellular
|
in humoral you dont need a macrophage, the B cell does it on its own.
|
|
in humoral
|
the end cell just releases a protein, the cell itself doesnt do anything
|
|
antibody structure
|
stem region-doesnt change
light/heavy chain changes through every protein |
|
antibody diversity
|
-immune system capable of as many as 1 Trillion different antibodies
|
|
somatic recombination
|
DNA segments shuffled and form new combinations of base sequences to produce antobody genes
|
|
somatic hypermutation
|
B cells in lymph nodules rapidly mutate creating new sequence
|
|
humoral immunity
ATTACK |
Neutrolization
compliment fixation agglutination precipitation |
|
neutrolization
|
antibodies mask pathogenic region at antigen
|
|
compliment fixation
|
antigens bond to LgM or lgG, antibody changes shape, initiate complement binding; primary defense against foreign cells, bacteria
|
|
Agglutination
|
Antibody has 2-10 binding sites, binds to multiple enemy cells, immobilizing them
|
|
Precipitation
|
antibody binds antigen molecules (not cells) : create antigen-antibody complex that precipitates, phagocytized by eusonophils
|