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16 Cards in this Set
- Front
- Back
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life of a stem cell
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stem cells in red bone marroe mature in thymus or bone marrow. then deployed to carious organs (lymph nodes, spleen mucous membrane, ect)
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T cells produce
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receptors on their surface that will bind to specific antiens they may encounter
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t cells are made
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randomly, but must satisfy 2 important criteria:
1)must be able to bind MHC molecules(bind to antigen) -cant bind-garbage can bind-go to stage 2 2) must not react vigourosly to self antigens displayed in MHC complex -pass 2-good |
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antigen presenting cells
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T cells usually cannot recognize antigens by themselves and require the help of APC's
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major histocompatability complex
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MHC
the function depends on this protein -acts as cell ID tag |
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t cells attack
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foreign cells and diseased host cells, memory of antigen
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3 classes of T Cells
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cytotoxic T cells
Helper T Cells Memory T cells |
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cytotoxic t cells
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tc cells
carry out attack:AKA CD4 cells |
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Helper T Cells
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help promotes tc cell and B cell action and non specific deense mechanisms
AKA |
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Memory T cells
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provide immunity from future expoure to antigen
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cellular immunity
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antigen presenting cell phagocytizes the pathogen, then strips away the antigens and presents them
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recognition
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T or Th bind to antigen in MHC complex
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Costimulation
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T cells double check for costimulation proteins
-only presenting cells have costimulation protein |
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clonal selection
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T cell is Replicated
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Lethal Hit or Interlukin Secretion
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Tc cells bind to MHC-1 antigen complexes and kill them
-Th cells bind to MHC-11 antigen complexes, and secrete interlukens |
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humoral immunity
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recognition
attack |
