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10 Cards in this Set
- Front
- Back
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cyclin-dependent kinases
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enzymes that trigger the cell to divide. they are only active when attached to cyclin.
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density-dependence inhibition
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means that normal cells will know not to divide anymore if they are already surrounded by other cells. In cancer cells this is disabled.
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anchorage dependence
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means that normal cells will know not to divide anymore if they are not anchored to something. In cancer cells this is disabled.
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metastasis
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when cancer cells migrate to a new tissue and start a new tumor somewhere else in the body.
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RSV
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Rous sarcoma virus. the first tumor virus that was discovered, discovered in chickens.
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proto-oncogene
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a normal gene that codes for proteins necessary to help the cell go through mitosis like it is supposed to.
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oncogene
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a proto-oncogene that has been mutated so that it is overexpressed, causing the cell to constantly keep dividing.
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tumor-suppressor genes
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genes that prevent uncontrolled cell division by stopping the cell cycle at certain checkpoints, and by causing apoptosis if something goes wrong
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apoptosis
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"programmed cell death" when the cell triggers its own death, because something went wrong in the cell that makes the cell dangerous to the organisms (for example, the cell lost control over division)
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HeLa cells
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cervical cancer cells from Henrietta Lacks. the first human cell line to live indefinitely in culture.
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