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31 Cards in this Set

  • Front
  • Back
Explain the effects of nerve compression
1. Occludes blood vessels
2. Arterial blood slows and stops because of pressure in vessels
3. Ischemia - hypoxia locally
What happens when remove nerve compression?
Re-perfusion injury when circulation re-esatblished. Flush out metabolites. Free radicals generated --> INFLAMMATION
What is the effect of nerve compression on myelin?
Segmental demyleination due to damaged perineurium -
What is polio?
Virus that causes inflammation of the central nervous system especially the anterior horn cells of the spinal cord and the brainstem - can lead to parestheisa and paralysis
What is leprosy?
Progressing bacterial infection which affects the skin and peripheral nerves in hands and feet. Causes loss of sensation and fingers and toes become mutilated and fall off
Effects of brief periods of nerve compression?
Focal demyelination --> conduction block
Effects of severe nerve compression?
Causes axonal interruption leading to Wallerian degeneration of the axon
What is Wallerian degeneration?
Results when an axon is cut or crushed, in which part of the axon separated from the neuron's cell body degenerates distal to the injury.
Effects of local nerve compression?
Small vessel occlusion - ishaemia
What are autonomic neuropathies?
Disease of nerves affecting internal organs
Severe burning pain (causalgia)
How would you define strength?
Ability to generate sufficient tension in a muscle for the purpose of posture and movement
How would you define weakness?
Inability to generate normal levels of force
What is paralysis?
Total loss of muscle activity
What is paraplegia?
Severe loss of motor activity
What is Paraparesis?
Mild or partial loss of muscle activity
What is quadriplegia?
Paralysis of all four limbs
What is paraplegia?
Paralysis of two lower limbs
What is hemiplegia?
Paralysis of one side of the body. includes the upper limb. one side of the trunk and the upper limb
What is hemiparesis?
Weakness of one side of the body
What is anaesthesia?
loss of bodily sensation
What is paraesthesia?
Abnormal skin sensations - pins and needles
What happens if the corticospinal tract axons are cut?
The lower motor neuron has no voluntary stimuli from the cortex but still have reflexes from the Golgi tendon organs and intrafusal fibres
How does an upper motor neuron affect reflexes?
Decreases level of dampening on the lower motor neuron - INCREASED spinal reflexes
Definition of flaccid?
Complete loss of muscle tone
Definition of Hypotonia?
A reduction in the stiffness of a muscle to lengthening
What is spasticity?
Increase in tonic-stretch reflexes (muscle tone) with exaggerated tendon jerks, resulting from hyper excitability of the stretch reflex
What is rigidity?
Heightened resistance to passive movement of the limb
What is lead pipe rigidity?
constant resistance to movement throughout the entire range of movement
What is Cogwheel rigidity?
characterised by alternating episodes of resistance and relaxation as the extremity is passively moved through range of motion
Name the main upper motor neuron lesion symptoms
1. increased muscle tone
2. Increased spasticity
3. Hyperactivity of deep tendon reflexes
4. Paresis or plegia of specific movements
5. Spastic paralysis
Name the main lower motor neuron lesion symptoms
1. Loss of muscle tone
2. Hypotonia
3. Hyporeflexia or areflexia
4. paresis or plegia of individual muscles
5. Flaccid paralysis