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22 Cards in this Set

  • Front
  • Back
age of sleep theories
19th century
4 main theories of sleep
vascular=some said increase or decrease of blood to brain
neural= retraction/paralysis of neurons or expansion of neuron processes
chemical= lack of O2 or accumulation of toxic/fatiguing substances during W *hypnotoxic theory-->sleep factors
behavioral= decreased sensory stimulation or cortical inhibition *inhibition theory=something removed or inhibited in brain
sleep as passive state:
-S was regarded as an inactive state of the_____
but discovery of ___&______proved that inaccurate
-T or F there is NO real distinction between sleep and other states of quiescence (like hypnosis, coma, stupor, drunk etc)
-brain
-rem's & duality of S
-T
constantin von economo said different brain regions
started the field of
involved in controlling S W
study of the brain control of sleep
used (3) techniques to study brain regions generating S/W in animals (cats, rats)
-lesions/transections
-electrical stimulation/neural recordings
-pharmacological experiments to study
The work of ____(2) stimulated
electrophysiological research in the sleep field
moruzzi and magoun
stimulate RF=
wake
____showed the 1st to record electrical activity of the
human brain (EEG), showed differences during W and S
Berger
______ in a personal lab set up near his mansion
in Tuxedo Park, NY, studied S onset and overnight S,
described temporal organization of S and described 5 S
stages (A‐E) by using EEG
Loomis
Kleitman & Aserinsky discovered
REM sleep
studied napping in infants
monitored EEG continuously together with the EOG and
they observed the cyclical occurrence of periods of eye
movements
Kleitman & Dement
observed muscle atonia/PGO waves with REM/fast EEGs
introduced term paradoxical sleep
divided sleep into SWS and REM
Jouvet
development of sleep medicine involved 3 disorders
pickwickian syndrome (obesity hypoventilation syndrome)
restless leg syndrome
narcolepsy
Pickwickian syndrome
excessive sleepiness
Dement and others started the Association of Psychophysiological Study of Sleep built
common sleep scoring system
common sleep scoring system has huge impact on
sleep research/pathologies
Bulow and Ingward perform first
polysomnogram
Gerardy demonstrated
apnea during sleep
1970 definition of ___was given
obstructive sleep apnea
1960-1980 called
rapid advancement
*involved research bout OSA
Fatal Familial insomnia (FFI)=
neurodegenerative genetic disorder
no sleep, dysautonomia, dementia, death
prion disease degeneration of thalamus
1998-2000
discovery of hypocretins/orexins and cause of narcolepsy