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22 Cards in this Set
- Front
- Back
age of sleep theories
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19th century
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4 main theories of sleep
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vascular=some said increase or decrease of blood to brain
neural= retraction/paralysis of neurons or expansion of neuron processes chemical= lack of O2 or accumulation of toxic/fatiguing substances during W *hypnotoxic theory-->sleep factors behavioral= decreased sensory stimulation or cortical inhibition *inhibition theory=something removed or inhibited in brain |
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sleep as passive state:
-S was regarded as an inactive state of the_____ but discovery of ___&______proved that inaccurate -T or F there is NO real distinction between sleep and other states of quiescence (like hypnosis, coma, stupor, drunk etc) |
-brain
-rem's & duality of S -T |
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constantin von economo said different brain regions
started the field of |
involved in controlling S W
study of the brain control of sleep |
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used (3) techniques to study brain regions generating S/W in animals (cats, rats)
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-lesions/transections
-electrical stimulation/neural recordings -pharmacological experiments to study |
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The work of ____(2) stimulated
electrophysiological research in the sleep field |
moruzzi and magoun
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stimulate RF=
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wake
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____showed the 1st to record electrical activity of the
human brain (EEG), showed differences during W and S |
Berger
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______ in a personal lab set up near his mansion
in Tuxedo Park, NY, studied S onset and overnight S, described temporal organization of S and described 5 S stages (A‐E) by using EEG |
Loomis
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Kleitman & Aserinsky discovered
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REM sleep
studied napping in infants |
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monitored EEG continuously together with the EOG and
they observed the cyclical occurrence of periods of eye movements |
Kleitman & Dement
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observed muscle atonia/PGO waves with REM/fast EEGs
introduced term paradoxical sleep divided sleep into SWS and REM |
Jouvet
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development of sleep medicine involved 3 disorders
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pickwickian syndrome (obesity hypoventilation syndrome)
restless leg syndrome narcolepsy |
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Pickwickian syndrome
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excessive sleepiness
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Dement and others started the Association of Psychophysiological Study of Sleep built
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common sleep scoring system
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common sleep scoring system has huge impact on
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sleep research/pathologies
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Bulow and Ingward perform first
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polysomnogram
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Gerardy demonstrated
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apnea during sleep
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1970 definition of ___was given
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obstructive sleep apnea
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1960-1980 called
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rapid advancement
*involved research bout OSA |
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Fatal Familial insomnia (FFI)=
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neurodegenerative genetic disorder
no sleep, dysautonomia, dementia, death prion disease degeneration of thalamus |
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1998-2000
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discovery of hypocretins/orexins and cause of narcolepsy
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