• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/168

Click to flip

168 Cards in this Set

  • Front
  • Back
CYP 450 STIMULATORS
BARBITURATES
CARBAMAZAPINE
PHENYTOIN
RIFAMPIN
CYP 450 DAMPENERS
CIMETIDINE
ERYTHROMYCIN
ISONIAZID
GRAPEFRUIT
KETOCONAZOLE
ORGANOPHOSPHATE / ANTICHOLINESTERASE TOXICITY
ATROPINE
PRALIDOXIME (2-PAM)
ACETAMINOPHEN TOXICITY
N-ACETYLCYSTEINE
HEPARIN TOXICITY
PROTAMINE SULFATE
WARFARIN TOXICITY
VITAMIN K
FRESH FROZEN PLASMA (FFP)
T-PA AND STREPTOKINASE TOXICITY
AMINOCAPROIC ACID
OPIOID TOXICITY
NALOXONE (IV)
NALTREXONE (PO)
BENZODIAZEPINE TOXICITY

(BENZODIAZEPINE RECEPTOR BLOCKER)
FLUMAZENIL
INTERACTION WITH THIS DRUG REQUIRES DOSE REDUCTION OF 6-MP
ALLOPURINOL
MAY PROTECT AGAINST DOXORUBICIN CARDIO-TOXICITY BY CHELATING IRON
DEXRAZOXANE
DNA DESTROYER

PULMONARY FIBROSIS SIDE-EFFECT
BLEOMYCIN
BINDS AND PREVENTS TUBULIN DE-POLYMERIZATION (MITOTIC ARREST)
PACLITAXEL (TAXOL)
ANTI-ESTROGEN AGENT IN BREAST CANCER
TAMOXIFEN
5HT3 BLOCKERS

FOR CHEMOTHERAPEUTIC-INDUCED VOMITING
DOLASETRON
GRANISETRON
ODANSETRON
PALONOSETRON
ALKYLATING AGENT

PRODUCES DISULFRAM-LIKE RXN WITH BEER
PROCARBEZINE
INHIBITS PROLACTIN RELEASE
DOPAMINE
ACTH ANALOG

USED TO DIAGNOSE CORTICOSTEROID ABNORMALITY
COSYNTROPIN
ADH ANALOG

USED FOR DIABETES INSIPIDUS AND NOCTURNAL ENURESIS
DESMOPRESSIN (DDAVP)
POPULAR THYROID DRUG

(SYNTHROID AND LEVOXYL)
L-THYROXINE (T4)
USED FOR HYPERPARATHYROIDISM

BLOCKS THYROPEROXIDASE WHICH IODINATES TYROSINE RESIDUES OF THYROGLOBULIN

HIGH DOSES BLOCK T4 TO T3 CONVERSION

THIOAMIDE LESS LIKELY TO CROSS PLACENTA - CAUTION IN PREGNANCY
PROPYLTHIOURACIL (PTU)
CORTICOSTEROID SIDE-EFFECTS
OSTEOPENIA
IMPAIRED WOUND HEALING
RISK OF INFXN
INCREASED APPETITE
PEPTIC ULCER DISEASE
HPTN
EDEMA
EUPHORIA
PSYCHOSIS
DIURETIC

BLOCKS ALDOSTERONE RECEPTORS

MAY CAUSE HYPERKALEMIA AND GYNECOMASTIA
SPIRONOLACTONE
SELECTIVE ESTROGEN RECEPTOR MODULATOR (SERM)

PREVENTS OSTEOPOROSIS

BEING RESEARCHED FOR BREAST CANCER
RALOXIFENE
NON-STEROIDAL ESTROGEN BLOCKER

CAUSES CLEAR-CELL ADENOCARCINOMA OF VAGINA IN DAUGHTERS OF WOMEN WHO USED IT IN PREGNANCY
DIETHYLSTILBESTROL (DES)
TURNS INTO DHT VIA 5-ALPHA-REDUCTASE
TESTOSTERONE
PRODUCT OF PRO-INSULIN CLEAVAGE

USED TO ASSESS INSULIN PRODUCTION
C-PEPTIDE
LONG-ACTING INSULIN
ULTRALENTE (HUMULIN U)
TREATS TYPE 2 DM

RAPID AND TRANSIENT RELEASE OF INSULIN THROUGH CLOSURE OF ATP-SENSITIVE POTASSIUM CHANNEL

AMINO ACID DERIVATIVE
NATEGLINIDE
DECREASES BONE RESORPTION

USED INTRANASALLY

PREPARED FROM SALMON
CALCITONIN
CAUSES UTERINE CONTRACTION
OXYTOCIN
HISTAMINE RECEPTOR DISTRIBUTION
SMOOTH MUSCLE (H1)

STOMACH (H2)
HEART
MAST CELLS

NERVE ENDINGS (H3)
CNS
FIRST GEN ANTIHISTAMINE

VERY SEDATIVE
DIPHENHYDRAMINE
SECOND GEN ANTIHISTAMINES
CETERIZINE
FEXOFENADINE
LORATADINE
H2 BLOCKER WITH MANY DRUG-DRUG INTERACTIONS
CIMETIDINE
5HT-1D/1B AGONIST

USED FOR MIGRAINES
SUMATRIPTAN
NARATRIPTAN
RIZATRIPTAN
USED FOR POST-PARTUM BLEEDING
OXYTOCIN AND ERGONOVINE
USED FOR CARCINOID TUMORS
CYPROHEPTADINE
5HT-3 BLOCKER

HIGH INCIDENCE OF QT PROLONGATION

CONTRAINDICATED IN PATIENTS WITH HEART DISEASE
DOLASETRON
ERGOT ALKALOID

ILLICIT DRUG
LSD
DOPAMINE AGONIST

USED FOR HYPERPROLACTINEMIA
BROMOCRIPTINE
CAUSES PAIN AND EDEMA

INACTIVATED BY ACE
BRADYKININ
VASODILATOR

DEPLETES SUBSTANCE P
CAPSAICIN
ABORTION-CAUSING
PROSTAGLANDIN E1 (MISOPROSTOL)
PGE2
PGF2ALPHA
BLOCKS LIPOXYGENASE
ZILEUTON
USED IN PEDIATRICS TO MAINTAIN PATENCY OF DUCTUS ARTERIOSIS

USED FOR IMPOTENCE
PGE1 (ALPROSTADIL)
STIMULATES cGMP RESULTING IN VASCULAR SMOOTH MUSCLE RELAXATION
NITRIC OXIDE
MUSCARINIC BLOCKER

BRONCHODILATOR USED FOR ASTHMA & COPD
IPRATROPIUM
MAST CELL STABILIZER
CROMOLYN
LONG-TERM SIDE-EFFECT OF CORTICOSTEROIDS (>5 DAYS)
ADRENAL SUPPRESSION
(WEAN OFF SLOWLY TO COUNTER)
INHIBITS DNA GYRASE
QUINOLONE
USED FOR MRSA

BLOCKS PEPTIDOGLYCAN SYNTHESIS
VANCOMYCIN
MENINGITIS PROPHYLAXIS IN EXPOSED PATIENTS

ORANGE PEE
RIFAMPIN
USED TO DIAGNOSE PERIANAL ITCHING
SCOTCH-TAPE TECHNIQUE
USED FOR PINWORMS
MEBENDAZOLE
INHIBITS DIHYDROPTEROATE SYNTHASE
SULFONAMIDE
WIDE-SPEC ANTIBIOTIC

DRUG OF CHOICE FOR OTITIS MEDIA
AMOXACILLIN
DRUG OF CHOICE FOR PSEUDOMEMBRANOUS COLITIS, GIARDIA, BACTERIAL VAGINOSIS, AND TRICHOMONAS

DISULFRAM-LIKE RXN WITH BEER
METRONIDAZOLE
MAY CAUSE MEGALOBLASTIC ANEMIA
TRIMETHOPRIM
TB
(THINK RIPE)
RIFAMPIN
ISONIAZID
PYRAZINAMIDE
ETHAMBUTOL
DRUG OF CHOICE FOR INFLUENZA A & B
OSELTAMIVIR
ZANAMIVIR
DRUG OF CHOICE FOR RSV
RIBAVIRIN
MYELOSUPPRESSION SIDE-EFFECT
GANCICLOVIR
HIV ANTIVIRAL CLASS

SEVERE DRUG INTERACTIONS
PROTEASE INHIBITORS
DRUG OF CHOICE FOR GONORRHEA
CEFTRIAXONE
DRUG OF CHOICE FOR HERPES

ACTIVATES THYMIDINE KINASE
ACYCLOVIR
ANTIMICROBIALS

CAUSES HEMOLYSIS IN G6PD-DEFICIENT PATIENTS
SULFONAMIDES
ANTIBIOTIC

UTI PROPHYLAXIS
SULFAMETHOXAZOLE/TRIMETHOPRIM
DECREASE REM SLEEP

CAUTION IN PREGNANCY - CROSSES PLACENTA
BENZODIAZEPINES
METABOLIZED TO ACETALDEHYDE BY ALCOHOL DEHYDROGENASE AND MICROSOMAL ETHANOL-OXIDIZING SYSTEM (MEOS)

MEOS CAN INCREASE ACTIVITY RESULTING IN TOLERANCE
ETOH
PERIPHERAL NEUROPATHY

(HPTN, ANEMIA, MI)
CHRONIC BEER DRINKERS
GENERALIZED TONIC-CLONIC AND PARTIAL SEIZURES
VALPROIC ACID
PHENYTOIN
CARBAMAZEPINE
ABSENCE SIEZURES
ETHOSUXIMIDE
VALPROIC ACID
MYOCLONIC SIEZURES
VALPROIC ACID
STATUS EPILEPTICUS
DIAZEPAM OR LORAZEPAM (IV) FOLLOWED BY PHENYTOIN
SIEZURES

PAIN OF NEUROPATHIC ORIGIN
GABAPENTIN
MAY CAUSE GINGIVAL HYPERPLASIA, NYSTAGMUS, DIPLOPIA, AND ATAXIA
PHENYTOIN
MALIGNANT SX: MALIGNANT HYPERTHERMIA LIKELY CAUSED FROM HALOGENATED ANESTHETICS

ACTS ON SARCOPLASMIC RETICULUM OR SKELETAL MUSCLE
DANTROLENE
OPIOID

PARTIAL AWARENESS DURING SURGERY

USED IN HIGH-RISK HEART SURGERY

AVAILABLE TRANS-DERMALLY
FENTANYL
DRUG-INDUCED PARKINSONISM (IRREVERSIBLE)
RESERPINE
ANTIPSYCHOTICS
MPTP (BY PRODUCT OF ILLICIT MEPERIDINE ANALOG)
SIDE-EFFECTS OF DOPAMINE-BLOCKING ANTIPSYCHOTICS
EPS
HYPERPROLACTINEMIA
AMENNORHEA
GALACTORRHEA
NEUROEPILEPTIC MALIGNANT SX
SCHIZOPHRENIA

MANIA

PSYCHOSIS IN PATIENTS WITH DEMENTIA

CAUSES HIGH PROLACTIN LEVELS
RESPIRIDONE
ANTIPSYCHOTICS WITH STRONG AUTONOMIC EFFECTS
CHLORPROMAZINE
THIORIDAZINE
5HT-2A AGONIST

REFRACTORY SCHIZOPHRENIA

WEIGHT GAIN

AGRANULOCYTOSIS
CLOZAPINE
ANTIPSYCHOTIC THAT DOESN'T CAUSE TARDIVE DYSKINESIA
CLOZAPINE AND QUETIAPINE
BIPOLAR DISORDER

MAINLY ELIMINATED IN KIDNEYS

AVOID DIURETICS AND DEHYDRATION TO AVOID TOXIC BUILD-UP

TREMOR, SEDATION, ATAXIA, APHASIA, THYROID ENLARGEMENT, AND DIABETES INSIPIDUS
LITHIUM
TCA

CHRONIC PAIN

ENURESIS

OCD
IMIPRAMINE
UNICYCLIC ANTIDEPRESSANT

LEAST LIKELY TO EFFECT SEXUAL PERFORMANCE

MGMT OF NICOTINE WITHDRAWAL

DIZZINESS, DRY MOUTH, PSYCHOSIS, SIEZURES
BUPROPION
RECEPTORS THAT CLOSE CALCIUM CHANNELS RESULTING IN BLOCKED NEUROTRANSMITTER RELEASE IN PAIN TRANSMISSION
PRESYNAPTIC MU, DELTA, AND KAPPA RECEPTORS
TOLERANCE TO ALL EFFECTS OF OPIOID AGONISTS CAN DEVELOP WITH THE EXCEPTION OF:
MIOSIS, CONVULSIONS AND CONSTIPATION
OPIOID

USED FOR WITHDRAWAL STATES
METHADONE
OPIOID THAT CAN BE GIVEN BY MOUTH, IV, OR EPIDURALLY

DYSPNEA OF PULMONARY EDEMA
MORPHINE
MODERATE OPIOID AGONIST
CODEINE
HYDROCODONE
OXYCODONE
OPIOID BLOCKER

SHORT DURATION OF ACTION

GIVEN INTRAVENOUSLY

MAY CAUSE SEVERE, RAPID, AND INTENSE SYMPTOMS (ABSTINENCE SX) TO A RECOVERING ADDICT
NALOXONE
OPIOID BLOCKER

GIVEN ORALLY IN ALCOHOL DEPENDENCY PROGRAMS
NALTREXONE
DRUG ABUSE SIGNS
CHANGE IN:

PULSE
BLOOD PRESSURE
BREATHING
TEMPERATURE
SWEATING
BOWEL SIGNS
PUPILLARY RESPONSES
DATE RAPE DRUG
FLUNITRAZEPAM (ROHYPNOL)
CNS DEPRESSANTS
ETOH
BARBITURATES
BENZODIAZEPINES
NICOTINE ADDICTION
PATCHES
GUM
NASAL SPRAY
PSYCHOTHERAPY
BUPROPION
ACTIVE INGREDIENT IS THC

IMPAIRS JUDGEMENT, REFLEXES, PSYCHOMOTOR PERFORMANCE, BLOOD PRESSURE
MARIJUANA
DRY MOUTH IN SJOGRENS SX
PILOCARPINE
CEVIMELINE
CHOLINERGIC TOXICITY
DUMBELSS:

DIARRHEA
URINATION
MIOSIS
BRONCHOCONSTRICTION
EXCITATION OF CNS & MUSCLE
LACRIMATION
SALIVATION
SWEATING
TREATS MUSCARINIC SYMPTOMS FROM ORGANOPHOSPHATE OVERDOSE
ATROPINE
PARKINSONS AND EPS
BENZTROPINE
TRIHEXYPHENIDYL
MOTION SICKNESS
SCOPOLAMINE
PRODUCES MYDRIASIS AND CYCLOPLEGIA
ATROPINE
HOMATROPINE
TROPICAMIDE
BETA RECEPTOR DISTRIBUTION
YOU HAVE 1 HEART (1 BETA)

YOU HAVE 2 LUNGS (2 BETA)
ANAPHYLACTIC SHOCK
EPINEPHRINE
DECREASES BLOOD, INCREASES PRESSURE

LOCAL DECONGESTANT

TREATS SPINAL SHOCK
ALPHA 1 AGONISTS
ALPHA 1 AGONIST TOXICITY
HYPERTENSION
SELECTIVE ALPHA 1 BLOCKERS

USED FOR HPTN & BPH

MAY CAUSE FIRST DOSE ORTHOSTATIC HPTN
PRAZOSIN
TERAZOSIN
DOXAZOSIN
SELECTIVE BETA1 RECEPTOR BLOCKERS

USED TO TREAT ASTHMA IN PATIENTS WITH HEART PROBLEMS
ACEBUTOLOL
ATENOLOL
ESMOLOL
METOPROLOL
BETA BLOCKER

LACKS LOCAL ANESTHETIC ACTIVITY (DECREASES PROTECTIVE REFLEXES AND INCREASES THE RISK OF CORNEAL ULCERATION)

TREATS GLAUCOMA
TIMOLOL
BETA BLOCKERS

DECREASE AQUEOUS SECRETION
TIMOLOL (NONSELECTIVE)
BETAXOLOL (SELECTIVE)
INHIBIT ANGIOTENSIN-CONVERTING ENZYME (ACE)

MAY CAUSE A DRY COUGH & HYPERKALEMIA

CONTRAINDICATED IN PREGNANCY AND WITH POTASSIUM
ACE INHIBITORS
ACE INHIBITORS
CAPTOPRIL
ENALAPRIL
ANGIOTENSIN RECEPTOR BLOCKERS

NO ASSOCIATED DRY COUGH
LOSARTAN
VALSARTAN
SIDE-EFFECTS OF CALCIUM CHANNEL BLOCKERS
CONSTIPATION
EDEMA
HEADACHE
REDUCE HEART RATE, CONTRACTILITY, AND O2 DEMAND

MAY CAUSE BRADYCARDIA, SEXUAL DYSFUNCTION, LOW HDL, HI TRIGS
BETA BLOCKERS
CARDIO-SELECTIVE BETA 1 BLOCKERS
ATENOLOL
ACEBUTOLOL
METOPROLOL
ALPHA 1 SELECTIVE BLOCKERS
PRAZOSIN
TERAZOSIN
DOXAZOSIN
A1A SELECTIVE BLOCKER

TREATS BPH
TAMSULOSIN (FLOMAX)
MAY CAUSE:
ORTHOSTATIC HPTN (ESPECIALLY FIRST DOSE), REFLEX TACHYCARDIA
ALPHA BLOCKERS
CONTRAINDICATED IN GERIATRICS DUE TO POSSIBLE DEPRESSION
METHYLDOPA
LUPUS-LIKE SIDE-EFFECT
HYDRALAZINE
SIDE-EFFECTS:
PARESTHESIAS, URINE ALKYLIZATION (CALCIUM STONES), HYPOKALEMIA, ACIDOSIS, ENCEPHALOPATHY IN PATIENTS WITH HEPATIC IMPAIRMENT
ACETAZOLAMIDE
DRUGS THAT ACT ON THICK ASCENDING LIMB
LOOP DIURETICS
LOOP DIURETIC

MAY CAUSE HYPERURICEMIA, HYPOKALEMIA, OTOTOXICITY
FUROSEMIDE
LOOP DIURETICS LOOSE

THIAZIDE DIURETICS RETAIN
CALCIUM
ACT ON EARLY DISTAL CONVOLUTED TUBULE

MAY CAUSE HYPERURICEMIA, HYPOKALEMIA, AND HYPERGLYCEMIA
THIAZIDES (HYDROCHLOROTHIAZIDE)
DIURETICS THAT INHIBIT SODIUM/POTASSIUM EXCHANGE
POTASSIUM-SPARING DIURETICS
TREATS PRIMARY ALDOSTERONISM

MAY CAUSE GYNECOMASTIA, HYPERKALEMIA, AND IMPOTENCE
SPIRONOLACTONE
OSMOTIC DIURETIC THAT TREATS INTRACRANIAL PRESSURE
MANNITOL
ADH AGONIST USED FOR PITUITARY DIABETES INSIPIDUS
DESMOPRESSIN (DDAVP)
ANTI-ARRHYTHMIC SODIUM CHANNEL BLOCKERS
CLASS 1 (PROCAINAMIDE)
CLASS 2 (LIDOCAINE)
CLASS 3 (FLECAINIDE)
LUPUS-LIKE SX SIDE-EFFECT
PROCAINAMIDE
LIMITING SIDE-EFFECT OF QUINIDINE
PROLONGS QT INTERVAL
ACUTE VENTRICULAR ARRHYTHMIAS
LIDOCAINE
PROLONGATION OF QT CAN LEAD TO..
TORSADES DE POINTES
VASODILATOR THAT INHIBITS PHOSPHODIESTERASE-5, ENHANCES NITRIC OXIDE EFFECT
SILDENAFIL (VIAGRA)
RELAXES VASCULAR SMOOTH MUSCLE

LOW DOSE DILATES VEINS

HI DOSE DILATES ARTERIOLES
NITRATES
INCREASES ACTIVITY OF ANTITHROMBIN 3
HEPARIN (PTT)
MAY CAUSE GI BLEEDING
ASPIRIN
LYSE THROMBI BY CATALYZING FORMATION OF PLASMIN WHICH BINDS FIBRIN

USED FOR PE AND DVT
THROMBOLYTICS
AGENT FOR PERNICIOUS ANEMIA
CYANOCOBALAMIN (VIT B12)
AGENT FOR MEGALOBLASTIC ANEMIA (DOES NOT REVERSE NEUROLOGIC SYMPTOMS)

DECREASES NEURAL TUBE DEFECTS EN UTERO
FOLIC ACID
AGENT USED FOR ANEMIAS WITH RENAL FAILURE
ERYTHROPOIETIN
MAY CAUSE GI BLEEDING
ASPIRIN
LYSE THROMBI BY CATALYZING FORMATION OF PLASMIN WHICH BINDS FIBRIN

USED FOR PE AND DVT
THROMBOLYTICS
AGENT FOR PERNICIOUS ANEMIA
CYANOCOBALAMIN (VIT B12)
AGENT FOR MEGALOBLASTIC ANEMIA (DOES NOT REVERSE NEUROLOGIC SYMPTOMS)

DECREASES NEURAL TUBE DEFECTS EN UTERO
FOLIC ACID
AGENT USED FOR ANEMIAS WITH RENAL FAILURE
ERYTHROPOIETIN
MAY CAUSE GI BLEEDING
ASPIRIN
LYSE THROMBI BY CATALYZING FORMATION OF PLASMIN WHICH BINDS FIBRIN

USED FOR PE AND DVT
THROMBOLYTICS
AGENT FOR PERNICIOUS ANEMIA
CYANOCOBALAMIN (VIT B12)
AGENT FOR MEGALOBLASTIC ANEMIA (DOES NOT REVERSE NEUROLOGIC SYMPTOMS)

DECREASES NEURAL TUBE DEFECTS EN UTERO
FOLIC ACID
AGENT USED FOR ANEMIAS WITH RENAL FAILURE
ERYTHROPOIETIN
ENHANCED EFFECT FROM GRAPEFRUIT AND OTHER DRUGS INHIBIT CYTOCHROME P450 3A4

NEED TO MONITOR LFT'S
STATINS
DECREASES LIVER TRIG SYNTHESIS

MAY CAUSE CUTANEOUS FLUSH
NIACIN
INCREASE THE ACTIVITY OF LIPOPROTEIN LIPASE
FIBRATES (GEMFIBROZIL)
HELPS CLOSE PDA
INDOMETHACIN
ONLY HAS ANTIPYRETIC AND ANALGESIC PROPERTY
ACETAMINOPHEN
FOR RHEUMATIC DISEASE

SLOW-ACTING
DRUGS-MODIFYING ANTI-RHEUMATIC AGENTS (DMARDS)
NSAID USED IN GOUT
INDOMETHACIN
INHIBITS XANTHINE OXIDASE

TREATS CHRONIC GOUT
ALLOPURINOL
ABILITY OF A DRUG
EFFICACY
HORMONES THAT INTRACELLULAR RECEPTORS
THYROID HORMONES
STEROID HORMONES
USES A TRANSMEMBRANE RECEPTOR
INSULIN