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168 Cards in this Set
- Front
- Back
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CYP 450 STIMULATORS
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BARBITURATES
CARBAMAZAPINE PHENYTOIN RIFAMPIN |
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CYP 450 DAMPENERS
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CIMETIDINE
ERYTHROMYCIN ISONIAZID GRAPEFRUIT KETOCONAZOLE |
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ORGANOPHOSPHATE / ANTICHOLINESTERASE TOXICITY
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ATROPINE
PRALIDOXIME (2-PAM) |
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ACETAMINOPHEN TOXICITY
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N-ACETYLCYSTEINE
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HEPARIN TOXICITY
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PROTAMINE SULFATE
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WARFARIN TOXICITY
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VITAMIN K
FRESH FROZEN PLASMA (FFP) |
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T-PA AND STREPTOKINASE TOXICITY
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AMINOCAPROIC ACID
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OPIOID TOXICITY
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NALOXONE (IV)
NALTREXONE (PO) |
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BENZODIAZEPINE TOXICITY
(BENZODIAZEPINE RECEPTOR BLOCKER) |
FLUMAZENIL
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INTERACTION WITH THIS DRUG REQUIRES DOSE REDUCTION OF 6-MP
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ALLOPURINOL
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MAY PROTECT AGAINST DOXORUBICIN CARDIO-TOXICITY BY CHELATING IRON
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DEXRAZOXANE
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DNA DESTROYER
PULMONARY FIBROSIS SIDE-EFFECT |
BLEOMYCIN
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BINDS AND PREVENTS TUBULIN DE-POLYMERIZATION (MITOTIC ARREST)
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PACLITAXEL (TAXOL)
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ANTI-ESTROGEN AGENT IN BREAST CANCER
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TAMOXIFEN
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5HT3 BLOCKERS
FOR CHEMOTHERAPEUTIC-INDUCED VOMITING |
DOLASETRON
GRANISETRON ODANSETRON PALONOSETRON |
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ALKYLATING AGENT
PRODUCES DISULFRAM-LIKE RXN WITH BEER |
PROCARBEZINE
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INHIBITS PROLACTIN RELEASE
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DOPAMINE
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ACTH ANALOG
USED TO DIAGNOSE CORTICOSTEROID ABNORMALITY |
COSYNTROPIN
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ADH ANALOG
USED FOR DIABETES INSIPIDUS AND NOCTURNAL ENURESIS |
DESMOPRESSIN (DDAVP)
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POPULAR THYROID DRUG
(SYNTHROID AND LEVOXYL) |
L-THYROXINE (T4)
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USED FOR HYPERPARATHYROIDISM
BLOCKS THYROPEROXIDASE WHICH IODINATES TYROSINE RESIDUES OF THYROGLOBULIN HIGH DOSES BLOCK T4 TO T3 CONVERSION THIOAMIDE LESS LIKELY TO CROSS PLACENTA - CAUTION IN PREGNANCY |
PROPYLTHIOURACIL (PTU)
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CORTICOSTEROID SIDE-EFFECTS
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OSTEOPENIA
IMPAIRED WOUND HEALING RISK OF INFXN INCREASED APPETITE PEPTIC ULCER DISEASE HPTN EDEMA EUPHORIA PSYCHOSIS |
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DIURETIC
BLOCKS ALDOSTERONE RECEPTORS MAY CAUSE HYPERKALEMIA AND GYNECOMASTIA |
SPIRONOLACTONE
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SELECTIVE ESTROGEN RECEPTOR MODULATOR (SERM)
PREVENTS OSTEOPOROSIS BEING RESEARCHED FOR BREAST CANCER |
RALOXIFENE
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NON-STEROIDAL ESTROGEN BLOCKER
CAUSES CLEAR-CELL ADENOCARCINOMA OF VAGINA IN DAUGHTERS OF WOMEN WHO USED IT IN PREGNANCY |
DIETHYLSTILBESTROL (DES)
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TURNS INTO DHT VIA 5-ALPHA-REDUCTASE
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TESTOSTERONE
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PRODUCT OF PRO-INSULIN CLEAVAGE
USED TO ASSESS INSULIN PRODUCTION |
C-PEPTIDE
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LONG-ACTING INSULIN
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ULTRALENTE (HUMULIN U)
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TREATS TYPE 2 DM
RAPID AND TRANSIENT RELEASE OF INSULIN THROUGH CLOSURE OF ATP-SENSITIVE POTASSIUM CHANNEL AMINO ACID DERIVATIVE |
NATEGLINIDE
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DECREASES BONE RESORPTION
USED INTRANASALLY PREPARED FROM SALMON |
CALCITONIN
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CAUSES UTERINE CONTRACTION
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OXYTOCIN
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HISTAMINE RECEPTOR DISTRIBUTION
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SMOOTH MUSCLE (H1)
STOMACH (H2) HEART MAST CELLS NERVE ENDINGS (H3) CNS |
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FIRST GEN ANTIHISTAMINE
VERY SEDATIVE |
DIPHENHYDRAMINE
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SECOND GEN ANTIHISTAMINES
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CETERIZINE
FEXOFENADINE LORATADINE |
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H2 BLOCKER WITH MANY DRUG-DRUG INTERACTIONS
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CIMETIDINE
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5HT-1D/1B AGONIST
USED FOR MIGRAINES |
SUMATRIPTAN
NARATRIPTAN RIZATRIPTAN |
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USED FOR POST-PARTUM BLEEDING
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OXYTOCIN AND ERGONOVINE
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USED FOR CARCINOID TUMORS
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CYPROHEPTADINE
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5HT-3 BLOCKER
HIGH INCIDENCE OF QT PROLONGATION CONTRAINDICATED IN PATIENTS WITH HEART DISEASE |
DOLASETRON
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ERGOT ALKALOID
ILLICIT DRUG |
LSD
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DOPAMINE AGONIST
USED FOR HYPERPROLACTINEMIA |
BROMOCRIPTINE
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CAUSES PAIN AND EDEMA
INACTIVATED BY ACE |
BRADYKININ
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VASODILATOR
DEPLETES SUBSTANCE P |
CAPSAICIN
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ABORTION-CAUSING
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PROSTAGLANDIN E1 (MISOPROSTOL)
PGE2 PGF2ALPHA |
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BLOCKS LIPOXYGENASE
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ZILEUTON
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USED IN PEDIATRICS TO MAINTAIN PATENCY OF DUCTUS ARTERIOSIS
USED FOR IMPOTENCE |
PGE1 (ALPROSTADIL)
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STIMULATES cGMP RESULTING IN VASCULAR SMOOTH MUSCLE RELAXATION
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NITRIC OXIDE
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MUSCARINIC BLOCKER
BRONCHODILATOR USED FOR ASTHMA & COPD |
IPRATROPIUM
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MAST CELL STABILIZER
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CROMOLYN
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LONG-TERM SIDE-EFFECT OF CORTICOSTEROIDS (>5 DAYS)
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ADRENAL SUPPRESSION
(WEAN OFF SLOWLY TO COUNTER) |
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INHIBITS DNA GYRASE
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QUINOLONE
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USED FOR MRSA
BLOCKS PEPTIDOGLYCAN SYNTHESIS |
VANCOMYCIN
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MENINGITIS PROPHYLAXIS IN EXPOSED PATIENTS
ORANGE PEE |
RIFAMPIN
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USED TO DIAGNOSE PERIANAL ITCHING
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SCOTCH-TAPE TECHNIQUE
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USED FOR PINWORMS
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MEBENDAZOLE
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INHIBITS DIHYDROPTEROATE SYNTHASE
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SULFONAMIDE
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WIDE-SPEC ANTIBIOTIC
DRUG OF CHOICE FOR OTITIS MEDIA |
AMOXACILLIN
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DRUG OF CHOICE FOR PSEUDOMEMBRANOUS COLITIS, GIARDIA, BACTERIAL VAGINOSIS, AND TRICHOMONAS
DISULFRAM-LIKE RXN WITH BEER |
METRONIDAZOLE
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MAY CAUSE MEGALOBLASTIC ANEMIA
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TRIMETHOPRIM
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TB
(THINK RIPE) |
RIFAMPIN
ISONIAZID PYRAZINAMIDE ETHAMBUTOL |
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DRUG OF CHOICE FOR INFLUENZA A & B
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OSELTAMIVIR
ZANAMIVIR |
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DRUG OF CHOICE FOR RSV
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RIBAVIRIN
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MYELOSUPPRESSION SIDE-EFFECT
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GANCICLOVIR
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HIV ANTIVIRAL CLASS
SEVERE DRUG INTERACTIONS |
PROTEASE INHIBITORS
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DRUG OF CHOICE FOR GONORRHEA
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CEFTRIAXONE
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DRUG OF CHOICE FOR HERPES
ACTIVATES THYMIDINE KINASE |
ACYCLOVIR
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ANTIMICROBIALS
CAUSES HEMOLYSIS IN G6PD-DEFICIENT PATIENTS |
SULFONAMIDES
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ANTIBIOTIC
UTI PROPHYLAXIS |
SULFAMETHOXAZOLE/TRIMETHOPRIM
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DECREASE REM SLEEP
CAUTION IN PREGNANCY - CROSSES PLACENTA |
BENZODIAZEPINES
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METABOLIZED TO ACETALDEHYDE BY ALCOHOL DEHYDROGENASE AND MICROSOMAL ETHANOL-OXIDIZING SYSTEM (MEOS)
MEOS CAN INCREASE ACTIVITY RESULTING IN TOLERANCE |
ETOH
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PERIPHERAL NEUROPATHY
(HPTN, ANEMIA, MI) |
CHRONIC BEER DRINKERS
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GENERALIZED TONIC-CLONIC AND PARTIAL SEIZURES
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VALPROIC ACID
PHENYTOIN CARBAMAZEPINE |
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ABSENCE SIEZURES
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ETHOSUXIMIDE
VALPROIC ACID |
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MYOCLONIC SIEZURES
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VALPROIC ACID
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STATUS EPILEPTICUS
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DIAZEPAM OR LORAZEPAM (IV) FOLLOWED BY PHENYTOIN
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SIEZURES
PAIN OF NEUROPATHIC ORIGIN |
GABAPENTIN
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MAY CAUSE GINGIVAL HYPERPLASIA, NYSTAGMUS, DIPLOPIA, AND ATAXIA
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PHENYTOIN
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MALIGNANT SX: MALIGNANT HYPERTHERMIA LIKELY CAUSED FROM HALOGENATED ANESTHETICS
ACTS ON SARCOPLASMIC RETICULUM OR SKELETAL MUSCLE |
DANTROLENE
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OPIOID
PARTIAL AWARENESS DURING SURGERY USED IN HIGH-RISK HEART SURGERY AVAILABLE TRANS-DERMALLY |
FENTANYL
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DRUG-INDUCED PARKINSONISM (IRREVERSIBLE)
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RESERPINE
ANTIPSYCHOTICS MPTP (BY PRODUCT OF ILLICIT MEPERIDINE ANALOG) |
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SIDE-EFFECTS OF DOPAMINE-BLOCKING ANTIPSYCHOTICS
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EPS
HYPERPROLACTINEMIA AMENNORHEA GALACTORRHEA NEUROEPILEPTIC MALIGNANT SX |
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SCHIZOPHRENIA
MANIA PSYCHOSIS IN PATIENTS WITH DEMENTIA CAUSES HIGH PROLACTIN LEVELS |
RESPIRIDONE
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ANTIPSYCHOTICS WITH STRONG AUTONOMIC EFFECTS
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CHLORPROMAZINE
THIORIDAZINE |
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5HT-2A AGONIST
REFRACTORY SCHIZOPHRENIA WEIGHT GAIN AGRANULOCYTOSIS |
CLOZAPINE
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ANTIPSYCHOTIC THAT DOESN'T CAUSE TARDIVE DYSKINESIA
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CLOZAPINE AND QUETIAPINE
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BIPOLAR DISORDER
MAINLY ELIMINATED IN KIDNEYS AVOID DIURETICS AND DEHYDRATION TO AVOID TOXIC BUILD-UP TREMOR, SEDATION, ATAXIA, APHASIA, THYROID ENLARGEMENT, AND DIABETES INSIPIDUS |
LITHIUM
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TCA
CHRONIC PAIN ENURESIS OCD |
IMIPRAMINE
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UNICYCLIC ANTIDEPRESSANT
LEAST LIKELY TO EFFECT SEXUAL PERFORMANCE MGMT OF NICOTINE WITHDRAWAL DIZZINESS, DRY MOUTH, PSYCHOSIS, SIEZURES |
BUPROPION
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RECEPTORS THAT CLOSE CALCIUM CHANNELS RESULTING IN BLOCKED NEUROTRANSMITTER RELEASE IN PAIN TRANSMISSION
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PRESYNAPTIC MU, DELTA, AND KAPPA RECEPTORS
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TOLERANCE TO ALL EFFECTS OF OPIOID AGONISTS CAN DEVELOP WITH THE EXCEPTION OF:
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MIOSIS, CONVULSIONS AND CONSTIPATION
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OPIOID
USED FOR WITHDRAWAL STATES |
METHADONE
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OPIOID THAT CAN BE GIVEN BY MOUTH, IV, OR EPIDURALLY
DYSPNEA OF PULMONARY EDEMA |
MORPHINE
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MODERATE OPIOID AGONIST
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CODEINE
HYDROCODONE OXYCODONE |
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OPIOID BLOCKER
SHORT DURATION OF ACTION GIVEN INTRAVENOUSLY MAY CAUSE SEVERE, RAPID, AND INTENSE SYMPTOMS (ABSTINENCE SX) TO A RECOVERING ADDICT |
NALOXONE
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OPIOID BLOCKER
GIVEN ORALLY IN ALCOHOL DEPENDENCY PROGRAMS |
NALTREXONE
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DRUG ABUSE SIGNS
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CHANGE IN:
PULSE BLOOD PRESSURE BREATHING TEMPERATURE SWEATING BOWEL SIGNS PUPILLARY RESPONSES |
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DATE RAPE DRUG
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FLUNITRAZEPAM (ROHYPNOL)
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CNS DEPRESSANTS
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ETOH
BARBITURATES BENZODIAZEPINES |
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NICOTINE ADDICTION
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PATCHES
GUM NASAL SPRAY PSYCHOTHERAPY BUPROPION |
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ACTIVE INGREDIENT IS THC
IMPAIRS JUDGEMENT, REFLEXES, PSYCHOMOTOR PERFORMANCE, BLOOD PRESSURE |
MARIJUANA
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DRY MOUTH IN SJOGRENS SX
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PILOCARPINE
CEVIMELINE |
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CHOLINERGIC TOXICITY
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DUMBELSS:
DIARRHEA URINATION MIOSIS BRONCHOCONSTRICTION EXCITATION OF CNS & MUSCLE LACRIMATION SALIVATION SWEATING |
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TREATS MUSCARINIC SYMPTOMS FROM ORGANOPHOSPHATE OVERDOSE
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ATROPINE
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PARKINSONS AND EPS
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BENZTROPINE
TRIHEXYPHENIDYL |
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MOTION SICKNESS
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SCOPOLAMINE
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PRODUCES MYDRIASIS AND CYCLOPLEGIA
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ATROPINE
HOMATROPINE TROPICAMIDE |
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BETA RECEPTOR DISTRIBUTION
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YOU HAVE 1 HEART (1 BETA)
YOU HAVE 2 LUNGS (2 BETA) |
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ANAPHYLACTIC SHOCK
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EPINEPHRINE
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DECREASES BLOOD, INCREASES PRESSURE
LOCAL DECONGESTANT TREATS SPINAL SHOCK |
ALPHA 1 AGONISTS
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ALPHA 1 AGONIST TOXICITY
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HYPERTENSION
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SELECTIVE ALPHA 1 BLOCKERS
USED FOR HPTN & BPH MAY CAUSE FIRST DOSE ORTHOSTATIC HPTN |
PRAZOSIN
TERAZOSIN DOXAZOSIN |
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SELECTIVE BETA1 RECEPTOR BLOCKERS
USED TO TREAT ASTHMA IN PATIENTS WITH HEART PROBLEMS |
ACEBUTOLOL
ATENOLOL ESMOLOL METOPROLOL |
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BETA BLOCKER
LACKS LOCAL ANESTHETIC ACTIVITY (DECREASES PROTECTIVE REFLEXES AND INCREASES THE RISK OF CORNEAL ULCERATION) TREATS GLAUCOMA |
TIMOLOL
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BETA BLOCKERS
DECREASE AQUEOUS SECRETION |
TIMOLOL (NONSELECTIVE)
BETAXOLOL (SELECTIVE) |
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INHIBIT ANGIOTENSIN-CONVERTING ENZYME (ACE)
MAY CAUSE A DRY COUGH & HYPERKALEMIA CONTRAINDICATED IN PREGNANCY AND WITH POTASSIUM |
ACE INHIBITORS
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ACE INHIBITORS
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CAPTOPRIL
ENALAPRIL |
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ANGIOTENSIN RECEPTOR BLOCKERS
NO ASSOCIATED DRY COUGH |
LOSARTAN
VALSARTAN |
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SIDE-EFFECTS OF CALCIUM CHANNEL BLOCKERS
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CONSTIPATION
EDEMA HEADACHE |
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REDUCE HEART RATE, CONTRACTILITY, AND O2 DEMAND
MAY CAUSE BRADYCARDIA, SEXUAL DYSFUNCTION, LOW HDL, HI TRIGS |
BETA BLOCKERS
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CARDIO-SELECTIVE BETA 1 BLOCKERS
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ATENOLOL
ACEBUTOLOL METOPROLOL |
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ALPHA 1 SELECTIVE BLOCKERS
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PRAZOSIN
TERAZOSIN DOXAZOSIN |
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A1A SELECTIVE BLOCKER
TREATS BPH |
TAMSULOSIN (FLOMAX)
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MAY CAUSE:
ORTHOSTATIC HPTN (ESPECIALLY FIRST DOSE), REFLEX TACHYCARDIA |
ALPHA BLOCKERS
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CONTRAINDICATED IN GERIATRICS DUE TO POSSIBLE DEPRESSION
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METHYLDOPA
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LUPUS-LIKE SIDE-EFFECT
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HYDRALAZINE
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SIDE-EFFECTS:
PARESTHESIAS, URINE ALKYLIZATION (CALCIUM STONES), HYPOKALEMIA, ACIDOSIS, ENCEPHALOPATHY IN PATIENTS WITH HEPATIC IMPAIRMENT |
ACETAZOLAMIDE
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DRUGS THAT ACT ON THICK ASCENDING LIMB
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LOOP DIURETICS
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LOOP DIURETIC
MAY CAUSE HYPERURICEMIA, HYPOKALEMIA, OTOTOXICITY |
FUROSEMIDE
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LOOP DIURETICS LOOSE
THIAZIDE DIURETICS RETAIN |
CALCIUM
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ACT ON EARLY DISTAL CONVOLUTED TUBULE
MAY CAUSE HYPERURICEMIA, HYPOKALEMIA, AND HYPERGLYCEMIA |
THIAZIDES (HYDROCHLOROTHIAZIDE)
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DIURETICS THAT INHIBIT SODIUM/POTASSIUM EXCHANGE
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POTASSIUM-SPARING DIURETICS
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TREATS PRIMARY ALDOSTERONISM
MAY CAUSE GYNECOMASTIA, HYPERKALEMIA, AND IMPOTENCE |
SPIRONOLACTONE
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OSMOTIC DIURETIC THAT TREATS INTRACRANIAL PRESSURE
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MANNITOL
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ADH AGONIST USED FOR PITUITARY DIABETES INSIPIDUS
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DESMOPRESSIN (DDAVP)
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ANTI-ARRHYTHMIC SODIUM CHANNEL BLOCKERS
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CLASS 1 (PROCAINAMIDE)
CLASS 2 (LIDOCAINE) CLASS 3 (FLECAINIDE) |
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LUPUS-LIKE SX SIDE-EFFECT
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PROCAINAMIDE
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LIMITING SIDE-EFFECT OF QUINIDINE
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PROLONGS QT INTERVAL
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ACUTE VENTRICULAR ARRHYTHMIAS
|
LIDOCAINE
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PROLONGATION OF QT CAN LEAD TO..
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TORSADES DE POINTES
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VASODILATOR THAT INHIBITS PHOSPHODIESTERASE-5, ENHANCES NITRIC OXIDE EFFECT
|
SILDENAFIL (VIAGRA)
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RELAXES VASCULAR SMOOTH MUSCLE
LOW DOSE DILATES VEINS HI DOSE DILATES ARTERIOLES |
NITRATES
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INCREASES ACTIVITY OF ANTITHROMBIN 3
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HEPARIN (PTT)
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MAY CAUSE GI BLEEDING
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ASPIRIN
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LYSE THROMBI BY CATALYZING FORMATION OF PLASMIN WHICH BINDS FIBRIN
USED FOR PE AND DVT |
THROMBOLYTICS
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AGENT FOR PERNICIOUS ANEMIA
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CYANOCOBALAMIN (VIT B12)
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AGENT FOR MEGALOBLASTIC ANEMIA (DOES NOT REVERSE NEUROLOGIC SYMPTOMS)
DECREASES NEURAL TUBE DEFECTS EN UTERO |
FOLIC ACID
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AGENT USED FOR ANEMIAS WITH RENAL FAILURE
|
ERYTHROPOIETIN
|
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MAY CAUSE GI BLEEDING
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ASPIRIN
|
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LYSE THROMBI BY CATALYZING FORMATION OF PLASMIN WHICH BINDS FIBRIN
USED FOR PE AND DVT |
THROMBOLYTICS
|
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AGENT FOR PERNICIOUS ANEMIA
|
CYANOCOBALAMIN (VIT B12)
|
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AGENT FOR MEGALOBLASTIC ANEMIA (DOES NOT REVERSE NEUROLOGIC SYMPTOMS)
DECREASES NEURAL TUBE DEFECTS EN UTERO |
FOLIC ACID
|
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AGENT USED FOR ANEMIAS WITH RENAL FAILURE
|
ERYTHROPOIETIN
|
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MAY CAUSE GI BLEEDING
|
ASPIRIN
|
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LYSE THROMBI BY CATALYZING FORMATION OF PLASMIN WHICH BINDS FIBRIN
USED FOR PE AND DVT |
THROMBOLYTICS
|
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AGENT FOR PERNICIOUS ANEMIA
|
CYANOCOBALAMIN (VIT B12)
|
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AGENT FOR MEGALOBLASTIC ANEMIA (DOES NOT REVERSE NEUROLOGIC SYMPTOMS)
DECREASES NEURAL TUBE DEFECTS EN UTERO |
FOLIC ACID
|
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AGENT USED FOR ANEMIAS WITH RENAL FAILURE
|
ERYTHROPOIETIN
|
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ENHANCED EFFECT FROM GRAPEFRUIT AND OTHER DRUGS INHIBIT CYTOCHROME P450 3A4
NEED TO MONITOR LFT'S |
STATINS
|
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DECREASES LIVER TRIG SYNTHESIS
MAY CAUSE CUTANEOUS FLUSH |
NIACIN
|
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INCREASE THE ACTIVITY OF LIPOPROTEIN LIPASE
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FIBRATES (GEMFIBROZIL)
|
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HELPS CLOSE PDA
|
INDOMETHACIN
|
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ONLY HAS ANTIPYRETIC AND ANALGESIC PROPERTY
|
ACETAMINOPHEN
|
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FOR RHEUMATIC DISEASE
SLOW-ACTING |
DRUGS-MODIFYING ANTI-RHEUMATIC AGENTS (DMARDS)
|
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NSAID USED IN GOUT
|
INDOMETHACIN
|
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INHIBITS XANTHINE OXIDASE
TREATS CHRONIC GOUT |
ALLOPURINOL
|
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ABILITY OF A DRUG
|
EFFICACY
|
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HORMONES THAT INTRACELLULAR RECEPTORS
|
THYROID HORMONES
STEROID HORMONES |
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USES A TRANSMEMBRANE RECEPTOR
|
INSULIN
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