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30 Cards in this Set

  • Front
  • Back
coverage of penicillins?
G+
all cocci
spirochetes
coverage of aminopenicillins (amoxicillin and ampicillin)?
G+
HaPLESS creatures
H. influenzae
a
Proteus
Listeria
E. coli
Salmonella
Shigella
name the anti-staphylococcals.
nafcillin
oxacillin
cloxacillin
dicloxacillin
which of the anti-pseudomonals causes platelet dysfunction?
ticarcillin
name the anti-pseudomonal penicillins.
TICarcillin
CARbenicillin
PIPeracillin
what is a famous side effect of ampicillin?
pseudomembranous colitis
as you move from first to fourth generation cephalosporin, what changes?
decr gram pos. coverage
incr. gram neg. coverage
incr. CNS penetration
incr. resistance to beta-lactamase
cephalosporins are inactive against which bugs?
enterococci
MRSA
Listeria monocytogenes
Clostridium difficile
what is aztreonam? against what bug is it good for?
cell wall synthesis inhibitor

aerobic gram neg. rods
Pseudomonas
Klebsiella
Serratia
what is the coverage of 1st generation cephalosporins?
G+ cocci (not MRSA)

some G- bacilli
(Proteus, E. coli, Klebsiella)
name 2 1st generation cephalosporins.
cephalexin
cefazolin
what 2nd generation cephalosporin is good against anaerobes, esp. B. fragilis. Also good with intra-abdominal sepsis and gyn sepsis.
cefoxitin

"goes into the FOX hole"
what is the coverage of 2nd generation cephalosporins?
same as first plus HEN

H. influenzae
Enterbacter
N. gonorrhea
name 4 second gen. cephalosporins.
cefoxitin
cefuroxime
cefotetan
cefaclor
what is the 4th generation cephalosporin? what does it cover?
cefepine

Pseudomonas and expanded G+ and G- over the 3rd generation
which 3rd gen cephalosporin works against pseudomonas?
cefTAZidime
what is the coverage of 3rd gen. cephalosporins?
N. gonorrhea

Klebsiella
Enterobacter
E. coli
Proteus

H. influenza
name 3 third generation cephalosporins.
cefTAZidime
cefTAXime
cefTRIaxone
name the aminoglycosides. what do they cover?
Streptomycin
Tobramycin
Amikacin
Neomycin
Gentamycin

G- enterics
name the tetracyclines. what do they cover?
tetracycline
doxycycline
demeclocycline

first-line agents for CRaM
Chlamydia
Rickettsia
a
Mycobacterium
and Borrelia
what antibiotic is used to treat SIADH?
demeclocycline
what is spectinomycin used for?
N. gonorrhea in pts allergic to ceftriaxone
uses for chloramphenicol?
Rickettsia
H. influenzae
N. meningitidis
Bacteroides
name the macrolides.
Macrolides:
Azithromycin
Clarithromycin
Erythromycin
coverage of erythromycin?
same as penicillin (used in penallergic pts) plus
B a CLaM

(think 'air'ythromycin)
B. pertussis
C. trachomatis, C. diphteria
Legionella
Mycoplasma
coverage of azithromycin?
Air bugs (resp)

H. influenzae
M. catarrhalis
MAI (first line)
coverage of clarithromycin?
extends erythromycin to include

H. influenza
N. gonorrhea
H. pylori
MAI
coverage of clindamycin?
toxicity?
severe infx by anaerobic bacteria like B. fragilis and C. perfringens

pseudomembranous colitis
name 3 fluoroquinolones.
levofloxacin
ciprofloxacin
moxifloxacin
what are the major uses of the fluoroquinolones?
tract infx:
- urinary tract (also STDs)
- respiratory tract
- GI tract
- eye tract
- skin, bone and soft tissue