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48 Cards in this Set
- Front
- Back
- 3rd side (hint)
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platelet
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what are the arrows pointing to?
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giant platelets
Post spleenectomy is most common reason to find them Also mb dt: May-Hegglin, leukemic myelofibrosis. |
what are the arrows pointing to?
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segmented neutrophil
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what is the arrow pointing to?
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usually only one seen in an RBC. DNA nuclear fragments.
Found in megaloblastic anemia, sickle-cell anemia, and post splenectomy. |
Erythrocyte Howell-Jolly bodies:
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segmented neutrophils
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what is the arrow pointing to?
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Band
The indentation is greater than 1/2 of the width of the hypothetical round nucleus. Opposite edges of nucleus become parallel giving horseshoe appearance. |
what is the arrowing pointing to?
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Band
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what is this? (arrow)
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Neutrophilic bands constitute what percentage of WBCs in a normal peripheral blood smear?
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1-5%
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the seg is on the left, the band on the right
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which is the segmented neutrophil and which is the neutrophilic band?
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Dohle bodies, RER residual aggregates, but may increase in infectious dz, burns, cytotoxic chemicals, poisons.
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what are the pale blue inclusions in these cells' cytoplasm?
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Hypersegmented neutrophils (5 or more lobes)
Due to decreased B12 and Folate. |
what type of WBCs are these? what causes them to look like this?
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Peutz-Huet anomaly.
Hereditary anomaly characterized by hypolobulation of the nucleus of granulocytes. Pince-nez (bottom left). |
I.D. these cells
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neutrophilic metamyelocyte.
slightly indented nucleus, small pinkish-blue granules. Rarely seen in normal peripheral blood. |
what is this WBC?
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lymphocytes
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what are these (arrows)?
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Clumped nuclear chromatin, dark stained.
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what is the diameter of a lymphocyte?
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small: 7-10 micron range.
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lymphocyte
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what is this?
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Clumped nuclear chromatin, dark stained.
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lymphocytes
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what are the arrows pointing to?
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Clumped nuclear chromatin, dark stained.
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lymphocyte (small, mature)
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what is this?
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Clumped nuclear chromatin, dark stained.
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lymphocytes
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what are the arrows pointing to?
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Clumped nuclear chromatin, dark stained.
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infectious mononucleosis
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what is this showing?
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Plasmalike cells with indented nuclei and “early” loose nuclear structure.
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basophil
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what is this?
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these WBCs have grains of histamine and heparin, are NOT phagocytic and normally are less than 1 per 100 in peripheral cells
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basophil
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neutrophil
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what is this?
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these prominent purplish and blue-black granules are associated with what?
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Toxic granulation: prominent purplish and blue-black granules, associated with severe infxn and other toxic states.
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eosinophil
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what is this?
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how do you identify an eosinophil?
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Granulocytes characterized by acid stain eosin readily as pink/red granules.
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what make up eosinophilic granules? what are they toxic to?
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major basic protein & eosinophilic cationic protein. they are toxic to several parasites.
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eosinophilia
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what is going on here?
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monocyte
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what is this?
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deeply indented nucleus, grey-blue cytoplasm “ground-glass” of lightly stained numerous fine granules.
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classic horse-shoe shaped monocyte
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what is this?
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ground glass appearance
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atypical monocyte
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what is this?
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monocyte
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what is this?
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bone marrow: monoblast
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what's this? (arrow)
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Monocytic leukemia: fine chromatin, visible nucleoli, and no cytoplasmic granules.
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Plasma cells. Maybe seen in young children, viral infx, herpes, EBV. Not seen in peripheral blood of healthy adult.
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what are these cells and when are they seen?
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Non-granular cyto stains a dark blue, no vacuoles, pale cyto adjacent to nucleus “peri-nuclear clear zone”
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macrocytes
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what are the arrows pointing to?
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when will you see macrocytes?
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B12 and folate deficiencies
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macrocytes
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what are the arrows pointing at?
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presence in the blood of erythrocytes with excessive variation in size
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anisocytosis
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spherocytes
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identify these cells.
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red blood cells with no area of central pallor like a normal red blood cell.
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hypochromic microcytic
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identify these rbcs
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teardrop (dacrocyte)
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identify the rbc (arrow)
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target cell (codocyte)
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identify this cell
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when will you see a target cell?
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Common in thalassemia, sickle-cell anemia, Hb-S thalassemia, other hemoglobinopathies
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target cells
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identify these cells
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ovalocytes/elliptocytes. A few is normal, but small #’s are seen in: iron deficiency, thalassemia, other hemoglobinopathies
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identify these cells and when are they seen?
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thin elongated eythrocytes with a point at each end. Schistocytes of all types may be found. Found in Hb-S Thal and Sickle Cell.
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Drepanocytes
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nucleated RBCs. Pernicious anemia & related B12-folic acid deficiency diseases. Usually see oval macrocytes and microcytes, and teardrops.
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identify these cells and when they are seen.
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sickle cells/drepanocytes
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identify these cells
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