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48 Cards in this Set

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platelet
what are the arrows pointing to?
giant platelets
Post spleenectomy is most common reason to find them
Also mb dt: May-Hegglin, leukemic myelofibrosis.
what are the arrows pointing to?
segmented neutrophil
what is the arrow pointing to?
usually only one seen in an RBC. DNA nuclear fragments.
Found in megaloblastic anemia, sickle-cell anemia, and post splenectomy.
Erythrocyte Howell-Jolly bodies:
segmented neutrophils
what is the arrow pointing to?
Band
The indentation is greater than 1/2 of the width of the hypothetical round nucleus. Opposite edges of nucleus become parallel giving horseshoe appearance.
what is the arrowing pointing to?
Band
what is this? (arrow)
Neutrophilic bands constitute what percentage of WBCs in a normal peripheral blood smear?
1-5%
the seg is on the left, the band on the right
which is the segmented neutrophil and which is the neutrophilic band?
Dohle bodies, RER residual aggregates, but may increase in infectious dz, burns, cytotoxic chemicals, poisons.
what are the pale blue inclusions in these cells' cytoplasm?
Hypersegmented neutrophils (5 or more lobes)
Due to decreased B12 and Folate.
what type of WBCs are these? what causes them to look like this?
Peutz-Huet anomaly.
Hereditary anomaly characterized by hypolobulation of the nucleus of granulocytes. Pince-nez (bottom left).
I.D. these cells
neutrophilic metamyelocyte.
slightly indented nucleus, small pinkish-blue granules. Rarely seen in normal peripheral blood.
what is this WBC?
lymphocytes
what are these (arrows)?
Clumped nuclear chromatin, dark stained.
what is the diameter of a lymphocyte?
small: 7-10 micron range.
lymphocyte
what is this?
Clumped nuclear chromatin, dark stained.
lymphocytes
what are the arrows pointing to?
Clumped nuclear chromatin, dark stained.
lymphocyte (small, mature)
what is this?
Clumped nuclear chromatin, dark stained.
lymphocytes
what are the arrows pointing to?
Clumped nuclear chromatin, dark stained.
infectious mononucleosis
what is this showing?
Plasmalike cells with indented nuclei and “early” loose nuclear structure.
basophil
what is this?
these WBCs have grains of histamine and heparin, are NOT phagocytic and normally are less than 1 per 100 in peripheral cells
basophil
neutrophil
what is this?
these prominent purplish and blue-black granules are associated with what?
Toxic granulation: prominent purplish and blue-black granules, associated with severe infxn and other toxic states.
eosinophil
what is this?
how do you identify an eosinophil?
Granulocytes characterized by acid stain eosin readily as pink/red granules.
what make up eosinophilic granules? what are they toxic to?
major basic protein & eosinophilic cationic protein. they are toxic to several parasites.
eosinophilia
what is going on here?
monocyte
what is this?
deeply indented nucleus, grey-blue cytoplasm “ground-glass” of lightly stained numerous fine granules.
classic horse-shoe shaped monocyte
what is this?
ground glass appearance
atypical monocyte
what is this?
monocyte
what is this?
bone marrow: monoblast
what's this? (arrow)
Monocytic leukemia: fine chromatin, visible nucleoli, and no cytoplasmic granules.
Plasma cells. Maybe seen in young children, viral infx, herpes, EBV. Not seen in peripheral blood of healthy adult.
what are these cells and when are they seen?
Non-granular cyto stains a dark blue, no vacuoles, pale cyto adjacent to nucleus “peri-nuclear clear zone”
macrocytes
what are the arrows pointing to?
when will you see macrocytes?
B12 and folate deficiencies
macrocytes
what are the arrows pointing at?
presence in the blood of erythrocytes with excessive variation in size
anisocytosis
spherocytes
identify these cells.
red blood cells with no area of central pallor like a normal red blood cell.
hypochromic microcytic
identify these rbcs
teardrop (dacrocyte)
identify the rbc (arrow)
target cell (codocyte)
identify this cell
when will you see a target cell?
Common in thalassemia, sickle-cell anemia, Hb-S thalassemia, other hemoglobinopathies
target cells
identify these cells
ovalocytes/elliptocytes. A few is normal, but small #’s are seen in: iron deficiency, thalassemia, other hemoglobinopathies
identify these cells and when are they seen?
thin elongated eythrocytes with a point at each end. Schistocytes of all types may be found. Found in Hb-S Thal and Sickle Cell.
Drepanocytes
nucleated RBCs. Pernicious anemia & related B12-folic acid deficiency diseases. Usually see oval macrocytes and microcytes, and teardrops.
identify these cells and when they are seen.
sickle cells/drepanocytes
identify these cells