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50 Cards in this Set
- Front
- Back
T/F--Neutrophilia is defined as a decrease in overall white blood cell numbers.
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false
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What are the myeloid cels that are right before the band neutrophils in normal maturation of the white blood cells?
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metamyelocyte
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Which WBC is the most abundant and is the body's first line of defense?
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Neutrophil
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What cells are considered agranulocytes?
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Lymphocytes and monocytes
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The cell with large round red granules in the dog would be
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eosinophil
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Which cell is primarily responsible for the immune response?
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Lymphocyte
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All blood cells arise from a
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stem cell.
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T/F-A right shift is when the number of WBC's are increased with immature cells present
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false
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Which of the white blood cells have granules that vary the most from species to species?
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eosinophil
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T/F-A band neutrophil is an immature WBC also known as a metamyelocyte
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false
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Neutrophils are produced in the blood stream over a period of
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hours
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________ granules vary in size and shape among different species.
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EOSINOPHIL
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The differential leukocyte count is expressed in both ________and_____ of each cell type per microliter of blood
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PERCENTAGE (RELATIVE) and ABSOLUTE NUMBERS
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When the marginal pool of neutrophils are mobilized into general circulation the term is known as
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NEUTROPHILIA OFTEN CAUSED BY STRESS AND THESE CELLS ARE KNOWN AS THE CIRCULATING GRANULOCYTE POOL.
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Phagocytes consist of the granulocytes, as well as the agranulocyte
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NEUTROPHILS, EOSINOPHILS and BASOPHILS THE MONOCYTE. |
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___________ are the cells are involved with cell mediated immunity.
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T LYMPHOCYTES
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Differential WBC counts should always be expressed in ____ numbers to be diagnostically useful.
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ABSOLUTE
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NRBC's are ________ in the total WBC count performed on hemocytometers and cell counters.
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COUNTED
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_________are small, blue-gray granules seen in toxic neutrophils.
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DOEHLE BODIES
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Which species has rod shaped granules in the cytoplasm of the eosinophils? FELINE
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feline
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A band neutrophil is more immature then a segmented neutrophil. ___________ is more immature then a band neutrophil.
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A METAMYELOCYTE
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Explain neutropenia.
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A DECREASED NUMBER OF NEUTROPHILS, USUALLY ASSOCIATED WITH A LEUKOPENIA
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Explain leukocytosis
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AN INCREASED NUMBER OF WHITE BLOOD CELLS
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Explain a left shift.
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AN INCREASED NUMBER OF IMMATURE NEUTROPHILS (BAND NEUTROPHILS)
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The granulocytes include
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NEUTROPHILS, EOSINOPHILS and BASOPHILS.
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The agranulocytes include
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MONOCYTES and LYMPHOCYTES.
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Which white blood cell is the most common and is the first one to come to the site of inflammation?
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NEUTROPHIL
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Explain band neutrophil.
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AN IMMATURE NEUTROPHIL
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What is normally the second most common WBC in peripheral blood?
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LYMPHOCYTE
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Which WBC is the largest and has nuclei of different shapes?
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MONOCYTE
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an arrangement of RBC that appear as a column or stack (common in equine, occ. in feline)
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rouleaux formation (can be seen in blood that is held too long, increased fibrinogen or globulin conc.)
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An abnormally high number of lymphocytes that is usually associated with infection, autoimmune disorders or certain cancers is called
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lymphocytosis
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A decrease in circulating lymphocytes is called
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lymphopenia (seen with sepsis, neoplasia, IMHA ect....)
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An increase in eosinophils (>750/ul) is called
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eosinophilia (allergies, parasites, adrenocorticoinsufficiency, myositis, panosteitis, degeneration of body tissue and proteins)
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An increase in neutrophil numbers is called
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neutrophilia
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A small intensely stained erythrocyte that has little to no central pallor- often seen with immune mediated hemolytic anemia
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spherocyte (spherocytosis- increase in number of spherocytes)
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Small round projections composed of denatured (due to oxidative injury) hemoglobin on the surface of a RBC
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Heinz bodies
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When are Heinz bodies seen?
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acetaminophen toxicities, onions, certain drugs and plants (stain with NMB)
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smaller than normal RBCs is called
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microcytes (seen with iron deficiency)
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A decrease in staining intensity due to a decrease in Hb in RBCs is known as______ and the cell will appear pale
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hypochromasia (seen with iron defecincy)
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Fragments of RBCs that look like pieces of acanthocytes, seen in DIC, hemangiosarcoma, and HW disease
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schistocytes
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Remnants of nuclear material found inside RBCs, seen during response to anemia (can be seen in response to spleendisorders)
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Howell-Jolly bodies
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clumping of RBCs (usually caused by cross-linking of RBC surface-associated antibodies)n (seen in autoimmune diseases)
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agglutination (to diff between rouleaux use the saline test/ rouleaux will disperse)
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A general term for an abnormal RBC shape
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poiklocytosis
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Variation in the size of RBCs
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anisocytosis
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Immature erythrocytes that contain clumps of organelles (retain basophilic staining material-RNA)- will stain with NBM
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reticulocytes
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A spiculated cell with irregular shaped projections (2-10) seen in liver disorders, hemangiosacromas, DIC and HW disease
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acanthocyte
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These cells are characterized by an increase membrane surface area relative to cell volume also known a target, bar or codocytes (seen in liver disorders, iron deficiency and reg, anemia)
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leptocyte
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a cell with a central area of pigment surrounded by a clear area and then a dense ring of peripheral cytoplasm
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target cell
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Increase in MCV, seen in young RBCs
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macrocytosis
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