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50 Cards in this Set

  • Front
  • Back
T/F--Neutrophilia is defined as a decrease in overall white blood cell numbers.
false
What are the myeloid cels that are right before the band neutrophils in normal maturation of the white blood cells?
metamyelocyte
Which WBC is the most abundant and is the body's first line of defense?
Neutrophil
What cells are considered agranulocytes?
Lymphocytes and monocytes
The cell with large round red granules in the dog would be
eosinophil
Which cell is primarily responsible for the immune response?
Lymphocyte
All blood cells arise from a
stem cell.
T/F-A right shift is when the number of WBC's are increased with immature cells present
false
Which of the white blood cells have granules that vary the most from species to species?
eosinophil
T/F-A band neutrophil is an immature WBC also known as a metamyelocyte
false
Neutrophils are produced in the blood stream over a period of
hours
________ granules vary in size and shape among different species.
EOSINOPHIL
The differential leukocyte count is expressed in both ________and_____ of each cell type per microliter of blood
PERCENTAGE (RELATIVE) and ABSOLUTE NUMBERS
When the marginal pool of neutrophils are mobilized into general circulation the term is known as
NEUTROPHILIA OFTEN CAUSED BY STRESS AND THESE CELLS ARE KNOWN AS THE CIRCULATING GRANULOCYTE POOL.
Phagocytes consist of the granulocytes, as well as the agranulocyte

NEUTROPHILS, EOSINOPHILS and BASOPHILS




THE MONOCYTE.

___________ are the cells are involved with cell mediated immunity.
T LYMPHOCYTES
Differential WBC counts should always be expressed in ____ numbers to be diagnostically useful.
ABSOLUTE
NRBC's are ________ in the total WBC count performed on hemocytometers and cell counters.
COUNTED
_________are small, blue-gray granules seen in toxic neutrophils.
DOEHLE BODIES
Which species has rod shaped granules in the cytoplasm of the eosinophils? FELINE
feline

A band neutrophil is more immature then a segmented neutrophil. ___________ is more immature then a band neutrophil.
A METAMYELOCYTE
Explain neutropenia.
A DECREASED NUMBER OF NEUTROPHILS, USUALLY ASSOCIATED WITH A LEUKOPENIA
Explain leukocytosis
AN INCREASED NUMBER OF WHITE BLOOD CELLS
Explain a left shift.
AN INCREASED NUMBER OF IMMATURE NEUTROPHILS (BAND NEUTROPHILS)
The granulocytes include
NEUTROPHILS, EOSINOPHILS and BASOPHILS.
The agranulocytes include
MONOCYTES and LYMPHOCYTES.
Which white blood cell is the most common and is the first one to come to the site of inflammation?
NEUTROPHIL
Explain band neutrophil.
AN IMMATURE NEUTROPHIL
What is normally the second most common WBC in peripheral blood?
LYMPHOCYTE
Which WBC is the largest and has nuclei of different shapes?
MONOCYTE
an arrangement of RBC that appear as a column or stack (common in equine, occ. in feline)
rouleaux formation (can be seen in blood that is held too long, increased fibrinogen or globulin conc.)
An abnormally high number of lymphocytes that is usually associated with infection, autoimmune disorders or certain cancers is called
lymphocytosis
A decrease in circulating lymphocytes is called
lymphopenia (seen with sepsis, neoplasia, IMHA ect....)
An increase in eosinophils (>750/ul) is called
eosinophilia (allergies, parasites, adrenocorticoinsufficiency, myositis, panosteitis, degeneration of body tissue and proteins)
An increase in neutrophil numbers is called
neutrophilia
A small intensely stained erythrocyte that has little to no central pallor- often seen with immune mediated hemolytic anemia
spherocyte (spherocytosis- increase in number of spherocytes)
Small round projections composed of denatured (due to oxidative injury) hemoglobin on the surface of a RBC
Heinz bodies
When are Heinz bodies seen?
acetaminophen toxicities, onions, certain drugs and plants (stain with NMB)
smaller than normal RBCs is called
microcytes (seen with iron deficiency)
A decrease in staining intensity due to a decrease in Hb in RBCs is known as______ and the cell will appear pale
hypochromasia (seen with iron defecincy)
Fragments of RBCs that look like pieces of acanthocytes, seen in DIC, hemangiosarcoma, and HW disease
schistocytes
Remnants of nuclear material found inside RBCs, seen during response to anemia (can be seen in response to spleendisorders)
Howell-Jolly bodies
clumping of RBCs (usually caused by cross-linking of RBC surface-associated antibodies)n (seen in autoimmune diseases)
agglutination (to diff between rouleaux use the saline test/ rouleaux will disperse)
A general term for an abnormal RBC shape
poiklocytosis
Variation in the size of RBCs
anisocytosis
Immature erythrocytes that contain clumps of organelles (retain basophilic staining material-RNA)- will stain with NBM
reticulocytes
A spiculated cell with irregular shaped projections (2-10) seen in liver disorders, hemangiosacromas, DIC and HW disease
acanthocyte
These cells are characterized by an increase membrane surface area relative to cell volume also known a target, bar or codocytes (seen in liver disorders, iron deficiency and reg, anemia)
leptocyte
a cell with a central area of pigment surrounded by a clear area and then a dense ring of peripheral cytoplasm
target cell
Increase in MCV, seen in young RBCs
macrocytosis